Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Sebastian Kandzia"'
Autor:
Cristina Escrevente, Nicolas Grammel, Sebastian Kandzia, Johannes Zeiser, Erin M Tranfield, Harald S Conradt, Júlia Costa
Publikováno v:
PLoS ONE, Vol 8, Iss 10, p e78631 (2013)
Exosomes consist of vesicles that are secreted by several human cells, including tumor cells and neurons, and they are found in several biological fluids. Exosomes have characteristic protein and lipid composition, however, the results concerning gly
Externí odkaz:
https://doaj.org/article/7a27588a28e8426285f355ea4e34ab83
Autor:
Harald S. Conradt, Maren Gatermann, Markus Glatzel, Júlia Costa, Manfred Nimtz, Sebastian Kandzia
Publikováno v:
Analytical Chemistry. 90:7871-7879
Cells release vesicles to the surroundings, the extracellular vesicles (EVs), which may transmit biomolecules to other cells, and are found in bodily fluids, thus constituting emerging biomarker targets. Many studies on EV nucleic acid, lipid, and pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eaf582dfcbb317468df7fbebdfb164c4
https://doi.org/10.1021/acs.analchem.7b05455
https://doi.org/10.1021/acs.analchem.7b05455
Autor:
Ricardo M. Gouveia, Ralf Kleene, Steven R. Head, Sebastian Kandzia, Lana Schaffer, Suzanne Papp, Melitta Schachner, Júlia Costa, Nicolas Grammel, Harald S. Conradt
Publikováno v:
Biochimica et Biophysica Acta (BBA) - General Subjects. 1820:2007-2019
Background Several glycan structures are functionally relevant in biological events associated with differentiation and regeneration which occur in the central nervous system. Here we have analysed the glycogene expression and glycosylation patterns
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::30361a6f373936364e7ceff4a227016d
https://doi.org/10.1016/j.bbagen.2012.09.004
https://doi.org/10.1016/j.bbagen.2012.09.004
Autor:
Srinivasa Rao, Deanna C. Hurum, Udayanath Aich, Lipika Basumallick, Jeffrey S. Rohrer, Christopher A. Pohl, Sebastian Kandzia
Publikováno v:
Analytical biochemistry. 458
Labeling of released asparagine-linked (N-linked) oligosaccharides from glycoproteins is commonly performed to aid in the separation and detection of the oligosaccharide. Of the many available oligosaccharide labels, 2-amino benzamide (2-AB) is a pop
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f56a11c673619d1c3093b4cac28fc255
https://pubmed.ncbi.nlm.nih.gov/24657360
https://pubmed.ncbi.nlm.nih.gov/24657360
Autor:
Sebastian, Kandzia, Júlia, Costa
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 1049
Changes in protein glycosylation are a hallmark of most types of cancer including ovarian carcinoma. The structural elucidation of glycans is technically challenging and it requires complementary chromatographic and spectroscopic techniques among oth
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::97c1f61187a3d308398fea89c733d2f1
https://pubmed.ncbi.nlm.nih.gov/23913225
https://pubmed.ncbi.nlm.nih.gov/23913225
Autor:
Sebastian Kandzia, Júlia Costa
Publikováno v:
Methods in Molecular Biology ISBN: 9781627035460
Changes in protein glycosylation are a hallmark of most types of cancer including ovarian carcinoma. The structural elucidation of glycans is technically challenging and it requires complementary chromatographic and spectroscopic techniques among oth
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0415ed66236d2bf5b9d736dacf34e0d6
https://doi.org/10.1007/978-1-62703-547-7_22
https://doi.org/10.1007/978-1-62703-547-7_22
Publikováno v:
Glycobiology. 21(3)
Ovarian carcinoma is the leading cause of death from gynecological cancers in many Western countries. Aberrant glycosylation is an important aspect in malignant transformation and consequently in ovarian cancer. In this study, a detailed structure an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ddc6881df86503d66680e47d79e2ffe
https://pubmed.ncbi.nlm.nih.gov/21030537
https://pubmed.ncbi.nlm.nih.gov/21030537
Publikováno v:
Cells and Culture ISBN: 9789048134182
The detailed knowledge of the N- and O-linked oligosaccharides of recombinantly produced human glycoprotein therapeutics is a prerequisite for their use in patients. From the regulatory point of view (EMEA, FDA), the carbohydrates of therapeutic glyc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f881789739412087d492c9044b4e1cb1
https://doi.org/10.1007/978-90-481-3419-9_151
https://doi.org/10.1007/978-90-481-3419-9_151
Publikováno v:
Cells and Culture ISBN: 9789048134182
The consistent and appropriate control of the quality of N-linked oligosaccharides of recombinant glycoproteins during fermentation is a major issue in successful commercial protein manufacture, and regulatory authorities (FDA, EMEA) put high require
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d28e112698bd17314fca8dfdecb53112
https://doi.org/10.1007/978-90-481-3419-9_152
https://doi.org/10.1007/978-90-481-3419-9_152
Publikováno v:
Journal of biotechnology. 145(2)
L1 is a cell adhesion molecule that is heavily glycosylated and is essential for normal development of the central nervous system. In this work, we compare the N -glycosylation of the L1 mutant that consists of immunoglobulin domains 5 and 6 (L1/Ig5
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e4c120e91431d54e64b5af8eb5da9fa
https://pubmed.ncbi.nlm.nih.gov/19922746
https://pubmed.ncbi.nlm.nih.gov/19922746