Výsledky vyhledávání - "Sebastian Kaluscha"

Evidence that direct inhibition of transcription factor binding is the prevailing mode of gene and repeat repression by DNA methylation

Autor: Sebastian Kaluscha, Silvia Domcke, Christiane Wirbelauer, Michael B. Stadler, Sevi Durdu, Lukas Burger, Dirk Schübeler

Publikováno v: Nature Genetics. 54:1895-1906

Cytosine methylation efficiently silences CpG-rich regulatory regions of genes and repeats in mammalian genomes. To what extent this entails direct inhibition of transcription factor (TF) binding versus indirect inhibition via recruitment of methyl-C

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2985aaf6b5aeebfcacdd0b9419894bd7
https://doi.org/10.1038/s41588-022-01241-6

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