Výsledky vyhledávání - "Sebastian Johannes Schober"

Akademický článek

No Improvement of Survival for Alveolar Rhabdomyosarcoma Patients After HLA-Matched Versus -Mismatched Allogeneic Hematopoietic Stem Cell Transplantation Compared to Standard-of-Care Therapy

Publikováno v: Frontiers in Oncology, Vol 12 (2022)

BackgroundPatients with stage IV alveolar rhabdomyosarcoma (RMA) have a 5-year-survival rate not exceeding 30%. Here, we assess the role of allogeneic hematopoietic stem cell transplantation (allo-HSCT) for these patients in comparison to standard-of

Externí odkaz: https://doaj.org/article/a5119f59a6ba4dc19070532c26ea5dc3

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The Oncolytic Adenovirus XVir-N-31 Joins Forces with CDK4/6 Inhibition Augmenting Innate and Adaptive Antitumor Immunity in Ewing Sarcoma

Autor: Sebastian Johannes Schober, Caroline Schoening, Jennifer Eck, Charlotte Middendorf, Julia Lutsch, Pia Knoch, Anna Josefine von Ofen, Hendrik Gassmann, Melanie Thiede, Julia Hauer, Andreas Kolk, Klaus Mantwill, Jürgen E. Gschwend, Stefan E.G. Burdach, Roman Nawroth, Uwe Thiel, Per Sonne Holm

Publikováno v: Clinical Cancer Research. 29:1996-2011

Purpose: Ewing sarcoma (EwS) is a highly malignant pediatric tumor characterized by a non-T-cell-inflamed immune-evasive phenotype. When relapsed or metastasized, survival is poor, emphasizing the need for novel treatment strategies. Here, we analyze

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::f08cb16f1b3cbe88ceb34bd7c71a636d
https://doi.org/10.1158/1078-0432.ccr-22-1961

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Data from The Oncolytic Adenovirus XVir-N-31 Joins Forces with CDK4/6 Inhibition Augmenting Innate and Adaptive Antitumor Immunity in Ewing Sarcoma

Autor: Per Sonne Holm, Uwe Thiel, Roman Nawroth, Stefan E.G. Burdach, Jürgen E. Gschwend, Klaus Mantwill, Andreas Kolk, Julia Hauer, Melanie Thiede, Hendrik Gassmann, Anna Josefine von Ofen, Pia Knoch, Julia Lutsch, Charlotte Middendorf, Jennifer Eck, Caroline Schoening, Sebastian Johannes Schober

Purpose:Ewing sarcoma (EwS) is a highly malignant pediatric tumor characterized by a non-T-cell-inflamed immune-evasive phenotype. When relapsed or metastasized, survival is poor, emphasizing the need for novel treatment strategies. Here, we analyze

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7436ec5ad0c442db9eb9dc93832cef20
https://doi.org/10.1158/1078-0432.c.6516382

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Figure S5 from The Oncolytic Adenovirus XVir-N-31 Joins Forces with CDK4/6 Inhibition Augmenting Innate and Adaptive Antitumor Immunity in Ewing Sarcoma

Supplemental Figure 5: Combination therapy of XVir-N-31 and CDK4/6 inhibitor LEE011 induces calreticulin (CALR) surface expression and increases phagocytosis in vitro.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c30b3a1b6f7542170fd4b4f64f32a8d
https://doi.org/10.1158/1078-0432.22820234.v1

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Supplementary Figure from Tumor Targeting with Bacterial Shiga Toxin B Subunit in Genetic Porcine Models for Colorectal Cancer and Osteosarcoma

Autor: Klaus-Peter Janssen, Angelika Schnieke, Ludger Johannes, Sebastian Johannes Schober, Dirk Wilhelm, Krzysztof Flisikowski, Laura Geyer, Anna Sichler, Noah-David Hirsch, Markus Perl, Tatiana Flisikowska, Anna Schrade, Maximilian Ehrenfeld

Supplementary Figure from Tumor Targeting with Bacterial Shiga Toxin B Subunit in Genetic Porcine Models for Colorectal Cancer and Osteosarcoma

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0194333dcef61ae0ae3ba9bb0f3f3c46
https://doi.org/10.1158/1535-7163.22522911.v1

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Supplementary Data from Tumor Targeting with Bacterial Shiga Toxin B Subunit in Genetic Porcine Models for Colorectal Cancer and Osteosarcoma

Supplementary Data from Tumor Targeting with Bacterial Shiga Toxin B Subunit in Genetic Porcine Models for Colorectal Cancer and Osteosarcoma

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::101326fed929706e5e51f7d396132fbd
https://doi.org/10.1158/1535-7163.22522923

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Data from Tumor Targeting with Bacterial Shiga Toxin B Subunit in Genetic Porcine Models for Colorectal Cancer and Osteosarcoma

The B subunit of bacterial Shiga toxin (STxB) is nontoxic and has low immunogenicity. Its receptor, the glycosphingolipid Gb3/CD77, is overexpressed on the cell surface of human colorectal cancer. We tested whether genetic porcine models, closely res

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a015928b83c2bb006746d915c0bfefd1
https://doi.org/10.1158/1535-7163.c.6543525

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Supplementary Information 1 from The Oncolytic Adenovirus XVir-N-31 Joins Forces with CDK4/6 Inhibition Augmenting Innate and Adaptive Antitumor Immunity in Ewing Sarcoma

Primers, antibodies and dyes

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::33d5779b7299b73e588d1d837b89e782
https://doi.org/10.1158/1078-0432.22438474

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Tumor Targeting with Bacterial Shiga Toxin B Subunit in Genetic Porcine Models for Colorectal Cancer and Osteosarcoma

Autor: Maximilian Ehrenfeld, Anna Schrade, Tatiana Flisikowska, Markus Perl, Noah-David Hirsch, Anna Sichler, Laura Geyer, Krzysztof Flisikowski, Dirk Wilhelm, Sebastian Johannes Schober, Ludger Johannes, Angelika Schnieke, Klaus-Peter Janssen

Publikováno v: Molecular cancer therapeutics. 21(4)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ff7c51139d4809b6ed1add249a2724b
https://pubmed.ncbi.nlm.nih.gov/35086950

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