Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Sebastian Joecks"'
Autor:
Solène Denolly, Alexey Stukalov, Uladzimir Barayeu, Alina N. Rosinski, Paraskevi Kritsiligkou, Sebastian Joecks, Tobias P. Dick, Andreas Pichlmair, Ralf Bartenschlager
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-20 (2023)
Abstract Zika virus (ZIKV) has emerged as a global health issue, yet neither antiviral therapy nor a vaccine are available. ZIKV is an enveloped RNA virus, replicating in the cytoplasm in close association with ER membranes. Here, we isolate ER membr
Externí odkaz:
https://doaj.org/article/e994d1107b8b43ba817ee5beb730274a
Autor:
Alina Matthaei, Sebastian Joecks, Annika Frauenstein, Janina Bruening, Dorothea Bankwitz, Martina Friesland, Gisa Gerold, Gabrielle Vieyres, Lars Kaderali, Felix Meissner, Thomas Pietschmann
Publikováno v:
Microbiology Spectrum, Vol 12, Iss 2 (2024)
ABSTRACTAssembly of infectious hepatitis C virus (HCV) particles requires multiple cellular proteins including for instance apolipoprotein E (ApoE). To describe these protein-protein interactions, we performed an affinity purification mass spectromet
Externí odkaz:
https://doaj.org/article/376bdc7a189e4ffe9567f56ee0bc03d1
Autor:
Christopher J. Neufeldt, Berati Cerikan, Mirko Cortese, Jamie Frankish, Ji-Young Lee, Agnieszka Plociennikowska, Florian Heigwer, Vibhu Prasad, Sebastian Joecks, Sandy S. Burkart, David Y. Zander, Baskaran Subramanian, Rayomand Gimi, Seetharamaiyer Padmanabhan, Radhakrishnan Iyer, Mathieu Gendarme, Bachir El Debs, Niels Halama, Uta Merle, Michael Boutros, Marco Binder, Ralf Bartenschlager
Publikováno v:
Communications Biology, Vol 5, Iss 1, Pp 1-15 (2022)
Neufeldt et al. evaluate transcriptional and cytokine secretion profiles of cells and patient sera following SARS-CoV-2 infection and detect distinct upregulation of inflammatory cytokines. They also demonstrate that this upregulation is mediated by
Externí odkaz:
https://doaj.org/article/e74d2975b29b4848bc2c7e84d04fd670
Autor:
Keisuke Tabata, Vibhu Prasad, David Paul, Ji-Young Lee, Minh-Tu Pham, Woan-Ing Twu, Christopher J. Neufeldt, Mirko Cortese, Berati Cerikan, Yannick Stahl, Sebastian Joecks, Cong Si Tran, Christian Lüchtenborg, Philip V’kovski, Katrin Hörmann, André C. Müller, Carolin Zitzmann, Uta Haselmann, Jürgen Beneke, Lars Kaderali, Holger Erfle, Volker Thiel, Volker Lohmann, Giulio Superti-Furga, Britta Brügger, Ralf Bartenschlager
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
Double membrane vesicles (DMV) are used as replication organelles by several RNA viruses. Applying proteomics and lipidomics, Tabata and Prasad et al. find that two cellular acyltransferases (AGPAT1/2), responsible for synthesis of phosphatidic acid,
Externí odkaz:
https://doaj.org/article/004cd836b49b455dbee0043b2c9d12d0
Autor:
Qinggong Yuan, Glenn Randall, Alexander Ploss, Dorothea Bankwitz, Chris Lauber, Tanvi Khera, Florian W. R. Vondran, Zoltán Ivics, Thomas Krey, Gabrielle Vieyres, Eleftherios Michailidis, Julie Sheldon, Eike Steinmann, Svenja M. Sake, Anggakusuma, Lieven Verhoye, Natascha Goedecke, Charles M. Rice, Birthe Tegtmeyer, Kathrin Welsch, Yudi Zhang, Gisa Gerold, Dagmar Wirth, Csaba Miskey, Michael Engelmann, Daniel Todt, Sebastian Joecks, Viet Loan Dao Thi, Yasmine Baktash, Philip Meuleman, Wolfgang Baumgärtner, Vanessa Herder, Thomas Pietschmann, C. Patrick McClure, Mohsan Saeed, Michael Ott, Romy Weller, Michael Seifert, Corinne Ginkel, Alexander W. Tarr, Richard J. C. Brown, Luisa J Ströh
Publikováno v:
Science Advances
eabd3233
Science advances, 6:eabd3233
SCIENCE ADVANCES
eabd3233
Science advances, 6:eabd3233
SCIENCE ADVANCES
Two transmembrane proteins cooperate to block infection of murine hepatocytes by human-tropic hepatitis C virus.
Hepatitis C virus (HCV) has no animal reservoir, infecting only humans. To investigate species barrier determinants limiting infecti
Hepatitis C virus (HCV) has no animal reservoir, infecting only humans. To investigate species barrier determinants limiting infecti
Autor:
Berati Cerikan, Sebastian Joecks, Ji-Young Lee, Mirko Cortese, Sandy S Burkart, Ralf Bartenschlager, Bachir El Debs, Marco Binder, Agnieszka Plociennikowska, Uta Merle, Michael Boutros, Christopher J. Neufeldt, Florian Heigwer, Jamie Frankish, Mathieu Gendarme, Niels Halama, David Yves Zander
SARS-CoV-2 is a novel virus that has rapidly spread, causing a global pandemic. In the majority of infected patients, SARS-CoV-2 leads to mild disease; however, in a significant proportion of infections, individuals develop severe symptoms that can l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d5e16f1b6dfbc52032a26eb137ba4bfa
https://doi.org/10.1101/2020.07.21.212639
https://doi.org/10.1101/2020.07.21.212639
Autor:
Kathrin Hueging, Florian W. R. Vondran, Thomas Pietschmann, Romy Weller, Sebastian Joecks, Daniel Todt, Richard J. C. Brown
Publikováno v:
Journal of virology
Journal of Virology
Journal of Virology
Hepatitis C virus (HCV) is extraordinarily diverse and uses entry factors in a strain-specific manner. Virus particles associate with lipoproteins, and apolipoprotein E (ApoE) is critical for HCV assembly and infectivity. However, whether ApoE depend