Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Sebastian Illes"'
Autor:
Julia Izsak, Henrik Seth, Margarita Iljin, Stephan Theiss, Hans Ågren, Keiko Funa, Ludwig Aigner, Eric Hanse, Sebastian Illes
Publikováno v:
Translational Psychiatry, Vol 11, Iss 1, Pp 1-15 (2021)
Abstract Lithium salts are used as mood-balancing medication prescribed to patients suffering from neuropsychiatric disorders, such as bipolar disorder and major depressive disorder. Lithium salts cross the blood-brain barrier and reach the brain par
Externí odkaz:
https://doaj.org/article/dfe9a2628cbc46949c5e6716415a69af
Autor:
Tugce Munise Satir, Lotta Agholme, Anna Karlsson, Mattias Karlsson, Paul Karila, Sebastian Illes, Petra Bergström, Henrik Zetterberg
Publikováno v:
Alzheimer’s Research & Therapy, Vol 12, Iss 1, Pp 1-9 (2020)
Abstract Background Alzheimer’s disease (AD) is the most common form of age-related neurodegenerative diseases. Cerebral deposition of Aβ peptides, especially Aβ42, is considered the major neuropathological hallmark of AD and the putative cause o
Externí odkaz:
https://doaj.org/article/18be0b7ebcbd444daeb1ef22eeb4f408
Autor:
Julia Izsak, Dzeneta Vizlin-Hodzic, Margarita Iljin, Joakim Strandberg, Janusz Jadasz, Thomas Olsson Bontell, Stephan Theiss, Eric Hanse, Hans Ågren, Keiko Funa, Sebastian Illes
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 8 (2020)
Persistent neural stem cell (NSC) proliferation is, among others, a hallmark of immaturity in human induced pluripotent stem cell (hiPSC)-based neural models. TGF-β1 is known to regulate NSCs in vivo during embryonic development in rodents. Here we
Externí odkaz:
https://doaj.org/article/66d945539ed34be099807ded70c1bc61
Autor:
Julia Izsak, Henrik Seth, Mats Andersson, Dzeneta Vizlin-Hodzic, Stephan Theiss, Eric Hanse, Hans Ågren, Keiko Funa, Sebastian Illes
Publikováno v:
Frontiers in Neuroscience, Vol 13 (2019)
Reproducibly generating human induced pluripotent stem cell-based functional neuronal circuits, solely obtained from single individuals, poses particular challenges to achieve personalized and patient specific functional neuronal in vitro models. A h
Externí odkaz:
https://doaj.org/article/dcf07ab44f4e414398710e2b811e1c71
Publikováno v:
Frontiers in Neural Circuits, Vol 12 (2018)
The cerebrospinal fluid (CSF) occupies the brain’s ventricles and subarachnoid space and, together with the interstitial fluid (ISF), forms a continuous fluidic network that bathes all cells of the central nervous system (CNS). As such, the CSF is
Externí odkaz:
https://doaj.org/article/c1b0cacbdb74494480582a6907075d9d
Autor:
Sebastian Illes, Martin Jakab, Felix Beyer, Renate Gelfert, Sébastien Couillard-Despres, Alfons Schnitzler, Markus Ritter, Ludwig Aigner
Publikováno v:
Stem Cell Reports, Vol 2, Iss 3, Pp 323-336 (2014)
Neurons generated from pluripotent stem cells (PSCs) self-organize into functional neuronal assemblies in vitro, generating synchronous network activities. Intriguingly, PSC-derived neuronal assemblies develop spontaneous activities that are independ
Externí odkaz:
https://doaj.org/article/79c16dc1226148279d532ee63d657e19
Oscillatory slow-wave activity (0.5—100 Hz) emerges during fetal human cortex development reflecting functional consequences of cellular brain ontogeny. Human induced pluripotent stem cell-derived (iPSC) neural in vitro models recapitulate aspects
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::635952bb0b57e7bf28d98ac3bce85239
https://doi.org/10.1101/2022.03.14.484311
https://doi.org/10.1101/2022.03.14.484311
Autor:
Paul Karila, Tugce Munise Satir, Anna Karlsson, Lotta Agholme, Petra Bergström, Henrik Zetterberg, Mattias Karlsson, Sebastian Illes
Publikováno v:
Alzheimer’s Research & Therapy, Vol 12, Iss 1, Pp 1-9 (2020)
Alzheimer's Research & Therapy
Alzheimer's Research & Therapy
Background Alzheimer’s disease (AD) is the most common form of age-related neurodegenerative diseases. Cerebral deposition of Aβ peptides, especially Aβ42, is considered the major neuropathological hallmark of AD and the putative cause of AD-rela
Autor:
Henrik Seth, Margarita Iljin, Eric Hanse, Sebastian Illes, Keiko Funa, Hans Ågren, Julia Izsak, Stephan Theiss, Ludwig Aigner
Publikováno v:
Translational Psychiatry, Vol 11, Iss 1, Pp 1-15 (2021)
Translational Psychiatry
Translational Psychiatry
Lithium salts are used as mood-balancing medication prescribed to patients suffering from neuropsychiatric disorders, such as bipolar disorder and major depressive disorder. Lithium salts cross the blood-brain barrier and reach the brain parenchyma w
Autor:
Tamaki Ishima, Brian Dean, Keiko Funa, Yoshimi Iwayama, Takeo Yoshikawa, Sebastian Illes, Hans Ågren, Kenji Hashimoto
Publikováno v:
Journal of affective disorders. 290
Background Brain-derived neurotrophic factor (BDNF) antisense RNA (BDNF-AS) was identified as naturally conserved non-coding antisense RNA that suppresses the transcription of BDNF. Methods We measured the expression of BDNF mRNA and BDNF-AS mRNA in