Zobrazeno 1 - 10
of 152
pro vyhledávání: '"Sebastian Huß"'
Autor:
Simon Lange, Anna Kuntze, Neele Wüstmann, Theresa Reckers, Verena Humberg, Wilhelm G. Dirks, Sebastian Huss, Julia Vieler, Andres Jan Schrader, Martin Bögemann, Katrin Schlack, Christof Bernemann
Publikováno v:
Biological Research, Vol 57, Iss 1, Pp 1-13 (2024)
Abstract Background Research on prostate cancer is mostly performed using cell lines derived from metastatic disease, not reflecting stages of tumor initiation or early progression. Establishment of cancer cell lines derived from the primary tumor si
Externí odkaz:
https://doaj.org/article/9adb8406bc7c41b0aaacef4df2b2900e
Autor:
Sebastian Huß, Zoran Nikoloski
Publikováno v:
Frontiers in Plant Science, Vol 14 (2023)
Quantification of reaction fluxes of metabolic networks can help us understand how the integration of different metabolic pathways determine cellular functions. Yet, intracellular fluxes cannot be measured directly but are estimated with metabolic fl
Externí odkaz:
https://doaj.org/article/b1b29d5c2a994d42ad782adbcf0dcd24
Publikováno v:
Thoracic Cancer, Vol 12, Iss 4, Pp 553-556 (2021)
Abstract About 40% of non‐small lung cancer (NSCLC) patients have metastatic disease at the time of diagnosis. However, metastatic NSCLC in the biliary duct system is extremely rare. A high proportion of patients with acute liver failure due to adv
Externí odkaz:
https://doaj.org/article/deb1d874b2ba48a0a960f3ff075729b6
Autor:
Arik Bernard Schulze, Lars Henning Schmidt, Birthe Heitkötter, Sebastian Huss, Michael Mohr, Alessandro Marra, Ludger Hillejan, Dennis Görlich, Peter J. Barth, Jan Rehkämper, Georg Evers
Publikováno v:
Thoracic Cancer, Vol 11, Iss 1, Pp 120-129 (2020)
Abstract Background Epithelial‐to‐mesenchymal transition (EMT) is a crucial step in lung cancer pathogenesis. Among others, cancer‐associated fibroblasts (CAFs) are reported to regulate this process. Objectives To investigate the prognostic and
Externí odkaz:
https://doaj.org/article/00133ab18bdc4c0d9e10576bb102f670
Publikováno v:
Cancers, Vol 15, Iss 1, p 262 (2022)
Objectives: To investigate the association of the prognostic risk score CAPRA&PDE4D5/7/9 as measured on pre-surgical diagnostic needle biopsy tissue with pathological outcomes after radical prostatectomies in a clinically low–intermediate-risk pati
Externí odkaz:
https://doaj.org/article/495f3d0502a94b79a27aac25e66f8f36
Autor:
Dianne van Strijp, Christiane de Witz, Birthe Heitkötter, Sebastian Huss, Martin Bögemann, George S. Baillie, Miles D. Houslay, Chris Bangma, Axel Semjonow, Ralf Hoffmann
Publikováno v:
Prostate Cancer, Vol 2019 (2019)
Objectives. To investigate the added value of assessing transcripts for the long cAMP phosphodiesterase-4D (PDE4D) isoforms, PDE4D5 and PDE4D9, regarding the prognostic power of the ‘CAPRA & PDE4D7’ combination risk model to predict longitudinal
Externí odkaz:
https://doaj.org/article/2a81cda05f6f4790873f44fc52c19088
Autor:
Michaela Angelika Ihle, Sebastian Huss, Wiebke Jeske, Wolfgang Hartmann, Sabine Merkelbach-Bruse, Hans-Ulrich Schildhaus, Reinhard Büttner, Harri Sihto, Kirsten Sundby Hall, Mikael Eriksson, Peter Reichardt, Heikki Joensuu, Eva Wardelmann
Publikováno v:
PLoS ONE, Vol 13, Iss 2, p e0193048 (2018)
Despite of multitude investigations no reliable prognostic immunohistochemical biomarkers in GIST have been established so far with added value to predict the recurrence risk of high risk GIST besides mitotic count, primary location and size. In this
Externí odkaz:
https://doaj.org/article/30be8344479e4755b5f7cc4da248a5a0
Autor:
Lars Henning Schmidt, Birthe Heitkötter, Arik B Schulze, Christoph Schliemann, Konrad Steinestel, Marcel Trautmann, Alessandro Marra, Ludger Hillejan, Michael Mohr, Georg Evers, Eva Wardelmann, Kambiz Rahbar, Dennis Görlich, Georg Lenz, Wolfgang E Berdel, Wolfgang Hartmann, Rainer Wiewrodt, Sebastian Huss
Publikováno v:
PLoS ONE, Vol 12, Iss 10, p e0186280 (2017)
PSMA (prostate-specific membrane antigen) is overexpressed in prostate cancer cells and is reported to be a promising target for antibody-based radioligand therapy in patients with metastasized prostate cancer. Since PSMA expression is not restricted
Externí odkaz:
https://doaj.org/article/4781c1f19a3b40168a2bfbc0cf16e24c
Autor:
Andreas Schröck, Friederike Göke, Patrick Wagner, Maike Bode, Alina Franzen, Martin Braun, Sebastian Huss, Abbas Agaimy, Stephan Ihrler, Ropika Menon, Robert Kirsten, Glen Kristiansen, Friedrich Bootz, Claudia Lengerke, Sven Perner
Publikováno v:
PLoS ONE, Vol 8, Iss 3, p e59201 (2013)
ObjectivesThe transcription factor SOX2 (3q26.3-q27) is an embryonic stem cell factor contributing to the induction of pluripotency in terminally differentiated somatic cells. Recently, amplification of the SOX2 gene locus has been described in squam
Externí odkaz:
https://doaj.org/article/95ac521457af477c8b19995ce451261d
Autor:
Daniel Holl, Peter Kuckenberg, Tatiana Woynecki, Angela Egert, Astrid Becker, Sebastian Huss, Dirk Stabenow, Andreas Zimmer, Percy Knolle, René Tolba, Hans-Peter Fischer, Hubert Schorle
Publikováno v:
PLoS ONE, Vol 6, Iss 7, p e22034 (2011)
BackgroundThe transcription factor Tcfap2c has been demonstrated to be essential for various processes during mammalian development. It has been found to be upregulated in various undifferentiated tumors and is implicated with poor prognosis. Tcfap2c
Externí odkaz:
https://doaj.org/article/173b8efce5f548cc942fd9a96206ad71