Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Sebastian Heinzmann"'
Autor:
Alexander Drilon, MD, Chao-Hua Chiu, MD, Yun Fan, MD, Byoung Chul Cho, MD, PhD, Shun Lu, MD, PhD, Myung-Ju Ahn, MD, PhD, Matthew G. Krebs, MD, PhD, Stephen V. Liu, MD, Thomas John, MD, Gregory A. Otterson, MD, Daniel S.W. Tan, MD, Tejas Patil, MD, Rafal Dziadziuszko, MD, PhD, Erminia Massarelli, MD, PhD, Takashi Seto, MD, Robert C. Doebele, MD, PhD, Bethany Pitcher, MSc, Nino Kurtsikidze, MD, Sebastian Heinzmann, PhD, Salvatore Siena, MD
Publikováno v:
JTO Clinical and Research Reports, Vol 3, Iss 6, Pp 100332- (2022)
Introduction: Entrectinib is an approved tyrosine kinase inhibitor (TKI) for ROS1 fusion–positive NSCLC. An updated integrated analysis of entrectinib from the ALKA-372-001, STARTRK-1, and STARTRK-2 trials is presented, with substantially longer fo
Externí odkaz:
https://doaj.org/article/46b674c9f39d4db4b8d61e682c4faee9
Autor:
Liam J Drew, Francois Rugiero, Paolo Cesare, Jonathan E Gale, Bjarke Abrahamsen, Sarah Bowden, Sebastian Heinzmann, Michelle Robinson, Andreas Brust, Barbara Colless, Richard J Lewis, John N Wood
Publikováno v:
PLoS ONE, Vol 2, Iss 6, p e515 (2007)
Little is known about the molecular basis of somatosensory mechanotransduction in mammals. We screened a library of peptide toxins for effects on mechanically activated currents in cultured dorsal root ganglion neurons. One conopeptide analogue, term
Externí odkaz:
https://doaj.org/article/b06e7269346846589e0b2a0296987146
Autor:
Christian Rolfo, Timothy R. Wilson, David Chen, Bethany Pitcher, Sebastian Heinzmann, Takashi Seto, Rafal Dziadziuszko, Sant P. Chawla, Marwan Fakih, Thomas John, Lyudmila Bazhenova, Jeeyun Lee, Koichi Goto, Jessica J. Lin, Chao-Hua Chiu, Myung-Ju Ahn, Stephen V. Liu, Byoung Chul Cho, Manish R. Patel, Salvatore Siena, Alexander Drilon, Filippo De Braud, George D. Demetri
Supplementary Data from Updated Integrated Analysis of the Efficacy and Safety of Entrectinib in Patients With NTRK Fusion-Positive Solid Tumors
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::355ea9fd232a8a92dbf396fdfbecec88
https://doi.org/10.1158/1078-0432.22487232.v1
https://doi.org/10.1158/1078-0432.22487232.v1
Autor:
Christian Rolfo, Timothy R. Wilson, David Chen, Bethany Pitcher, Sebastian Heinzmann, Takashi Seto, Rafal Dziadziuszko, Sant P. Chawla, Marwan Fakih, Thomas John, Lyudmila Bazhenova, Jeeyun Lee, Koichi Goto, Jessica J. Lin, Chao-Hua Chiu, Myung-Ju Ahn, Stephen V. Liu, Byoung Chul Cho, Manish R. Patel, Salvatore Siena, Alexander Drilon, Filippo De Braud, George D. Demetri
Supplementary Figure from Updated Integrated Analysis of the Efficacy and Safety of Entrectinib in Patients With NTRK Fusion-Positive Solid Tumors
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2001aba06000057aca74465b69779244
https://doi.org/10.1158/1078-0432.22487211
https://doi.org/10.1158/1078-0432.22487211
Autor:
Christian Rolfo, Timothy R. Wilson, David Chen, Bethany Pitcher, Sebastian Heinzmann, Takashi Seto, Rafal Dziadziuszko, Sant P. Chawla, Marwan Fakih, Thomas John, Lyudmila Bazhenova, Jeeyun Lee, Koichi Goto, Jessica J. Lin, Chao-Hua Chiu, Myung-Ju Ahn, Stephen V. Liu, Byoung Chul Cho, Manish R. Patel, Salvatore Siena, Alexander Drilon, Filippo De Braud, George D. Demetri
Purpose:Entrectinib potently inhibits tropomyosin receptor kinases (TRKAs)/B/C and ROS1, and previously induced deep [objective response rate (ORR) 57.4%] and durable [median duration of response (DoR) 10.4 months] responses in adults with NTRK fusio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::523adecf3e85de60eb376f882ac658fa
https://doi.org/10.1158/1078-0432.c.6532467
https://doi.org/10.1158/1078-0432.c.6532467
Autor:
Bowles Daniel W, Lyudmila Bazhenova, Segolene Hescot, Gunnar Folprecht, Haruko Daga, Erminia Massarelli, Conley Anthony P, Livia Lamartina, Jessica Lin, Eugene Ahn, Stuart Osborne, Sebastian Heinzmann, Daniel Carrizosa
Publikováno v:
Endocrine Abstracts.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c33593a22e302263a3b562f3b2b3ae80
https://doi.org/10.1530/endoabs.84.op-03-14
https://doi.org/10.1530/endoabs.84.op-03-14
Autor:
George D. Demetri, Filippo De Braud, Alexander Drilon, Salvatore Siena, Manish R. Patel, Byoung Chul Cho, Stephen V. Liu, Myung-Ju Ahn, Chao-Hua Chiu, Jessica J. Lin, Koichi Goto, Jeeyun Lee, Lyudmila Bazhenova, Thomas John, Marwan Fakih, Sant P. Chawla, Rafal Dziadziuszko, Takashi Seto, Sebastian Heinzmann, Bethany Pitcher, David Chen, Timothy R. Wilson, Christian Rolfo
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research, vol 28, iss 7
Purpose: Entrectinib potently inhibits tropomyosin receptor kinases (TRKAs)/B/C and ROS1, and previously induced deep [objective response rate (ORR) 57.4%] and durable [median duration of response (DoR) 10.4 months] responses in adults with NTRK fusi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3aa47e6bf8e1aa14128497f92320a8fb
https://escholarship.org/uc/item/62k9z94t
https://escholarship.org/uc/item/62k9z94t
Autor:
George D. Demetri, Filippo De Braud, Alexander Drilon, Salvatore Siena, Manish R. Patel, Byoung Chul Cho, Stephen V. Liu, Myung-Ju Ahn, Chao-Hua Chiu, Jessica J. Lin, Koichi Goto, Jeeyun Lee, Lyudmila Bazhenova, Thomas John, Marwan Fakih, Sant P. Chawla, Rafal Dziadziuszko, Takashi Seto, Sebastian Heinzmann, Bethany Pitcher, David Chen, Timothy R. Wilson, Christian Rolfo
Publikováno v:
Clinical Cancer Research. 28:2196-2196
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::161465fccaefda8544cf1d9b13004696
https://doi.org/10.1158/1078-0432.ccr-22-1108
https://doi.org/10.1158/1078-0432.ccr-22-1108
Publikováno v:
Current opinion in supportive and palliative care. 5(2)
To inform on preclinical and early clinical advances in the effort to identify novel classes of analgesic drugs.Human genetic and animal preclinical studies have identified several mechanisms that appear to make important contributions to abnormal pa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::283f7679e81d92510bdb5ad59d7ba5c5
https://pubmed.ncbi.nlm.nih.gov/21455071
https://pubmed.ncbi.nlm.nih.gov/21455071
Autor:
Paolo Cesare, Sebastian Heinzmann, Jonathan E. Gale, Michelle Robinson, Barbara Colless, Liam Drew, Andreas Brust, John N. Wood, Bjarke Abrahamsen, Francois Rugiero, Sarah Bowden, Richard J. Lewis
Publikováno v:
PLoS ONE, Vol 2, Iss 6, p e515 (2007)
PLoS ONE
PLoS ONE
Little is known about the molecular basis of somatosensory mechanotransduction in mammals. We screened a library of peptide toxins for effects on mechanically activated currents in cultured dorsal root ganglion neurons. One conopeptide analogue, term
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::213feb214b955bd377be23afb40dd82a
https://doi.org/10.1371/journal.pone.0000515
https://doi.org/10.1371/journal.pone.0000515