Zobrazeno 1 - 10
of 188
pro vyhledávání: '"Sebastian Haferkamp"'
Autor:
Gunther Glehr, Paloma Riquelme, Katharina Kronenberg, Robert Lohmayer, Víctor J. López-Madrona, Michael Kapinsky, Hans J. Schlitt, Edward K. Geissler, Rainer Spang, Sebastian Haferkamp, James A. Hutchinson
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-21 (2024)
Abstract Immunological diseases are typically heterogeneous in clinical presentation, severity and response to therapy. Biomarkers of immune diseases often reflect this variability, especially compared to their regulated behaviour in health. This lea
Externí odkaz:
https://doaj.org/article/f1e2e526f7134e5596f23916f7bf3b45
Autor:
Tanja Elger, Johanna Loibl, Christa Buechler, Sebastian Haferkamp, Jens Werner, Konstantin Drexler, Ulrich Hohenleutner, Karsten Guelow, Claudia Kunst, Arne Kandulski, Pia Goeggelmann, Martina Mueller, Hauke Christian Tews
Publikováno v:
Journal of Medical Case Reports, Vol 18, Iss 1, Pp 1-8 (2024)
Abstract Background Metastatic Crohn’s disease is a rare disorder characterized by various granulomatous skin lesions that occur independently of gastrointestinal tract involvement. However, currently there is no standardized care or specific treat
Externí odkaz:
https://doaj.org/article/1e3366e6a49143b1ac2c752c9c09a215
Autor:
Barbara Schwertner, George Dahdal, Wolfgang Jagla, Luis Grossmann, Konstantin Drexler, Michael P. Krahn, Katja Evert, Mark Berneburg, Sebastian Haferkamp, Christine Ziegler, Eric K. Parkinson, Grit Zahn, Maria E. Mycielska, Andreas Gaumann
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 12 (2024)
We have recently shown that cancer cells of various origins take up extracellular citrate through the plasma membrane citrate carrier (pmCiC), a specific plasma membrane citrate transporter. Extracellular citrate is required to support cancer cell me
Externí odkaz:
https://doaj.org/article/0e8a6ba44376475d8a649d023b9f0b09
Autor:
Theresa E. Schäfer, Lisanne I. Knol, Ferdinand V. Haas, Anna Hartley, Sophie C.S. Pernickel, Attila Jády, Maximiliane S.C. Finkbeiner, Johannes Achberger, Stella Arelaki, Živa Modic, Katrin Schröer, Wenli Zhang, Barbara Schmidt, Philipp Schuster, Sebastian Haferkamp, Johannes Doerner, Florian Gebauer, Maximilian Ackermann, Hans-Michael Kvasnicka, Amit Kulkarni, Selas T.F. Bots, Vera Kemp, Lukas J.A.C. Hawinkels, Anna R. Poetsch, Rob C. Hoeben, Anja Ehrhardt, Antonio Marchini, Guy Ungerechts, Claudia R. Ball, Christine E. Engeland
Publikováno v:
EBioMedicine, Vol 105, Iss , Pp 105219- (2024)
Summary: Background: Pancreatic ductal adenocarcinoma (PDAC) is a tumour entity with unmet medical need. To assess the therapeutic potential of oncolytic virotherapy (OVT) against PDAC, different oncolytic viruses (OVs) are currently investigated in
Externí odkaz:
https://doaj.org/article/06247aac10bb4534989e76e11402c612
Autor:
Elias A. T. Koch, Anne Petzold, Edgar Dippel, Michael Erdmann, Anja Gesierich, Ralf Gutzmer, Jessica C. Hassel, Sebastian Haferkamp, Katharina C. Kähler, Nicole Kreuzberg, Ulrike Leiter, Carmen Loquai, Friedegund Meier, Markus Meissner, Peter Mohr, Claudia Pföhler, Farnaz Rahimi, Beatrice Schell, Patrick Terheyden, Kai-Martin Thoms, Selma Ugurel, Jens Ulrich, Jochen Utikal, Michael Weichenthal, Fabian Ziller, Carola Berking, Markus V. Heppt
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
IntroductionDespite recent advancements in the treatment of metastatic uveal melanoma (UM), the availability of further treatment options remains limited and the prognosis continues to be poor in many cases. In addition to tebentafusp, immune checkpo
Externí odkaz:
https://doaj.org/article/e37aacd9f05d43b681af7a4bbdfeb024
Autor:
Tirtha Chanda, Katja Hauser, Sarah Hobelsberger, Tabea-Clara Bucher, Carina Nogueira Garcia, Christoph Wies, Harald Kittler, Philipp Tschandl, Cristian Navarrete-Dechent, Sebastian Podlipnik, Emmanouil Chousakos, Iva Crnaric, Jovana Majstorovic, Linda Alhajwan, Tanya Foreman, Sandra Peternel, Sergei Sarap, İrem Özdemir, Raymond L. Barnhill, Mar Llamas-Velasco, Gabriela Poch, Sören Korsing, Wiebke Sondermann, Frank Friedrich Gellrich, Markus V. Heppt, Michael Erdmann, Sebastian Haferkamp, Konstantin Drexler, Matthias Goebeler, Bastian Schilling, Jochen S. Utikal, Kamran Ghoreschi, Stefan Fröhling, Eva Krieghoff-Henning, Reader Study Consortium, Titus J. Brinker
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-17 (2024)
Abstract Artificial intelligence (AI) systems have been shown to help dermatologists diagnose melanoma more accurately, however they lack transparency, hindering user acceptance. Explainable AI (XAI) methods can help to increase transparency, yet oft
Externí odkaz:
https://doaj.org/article/a7c398cf0b3b4b35ad5fc17b7f22b907
Autor:
Konstantin Drexler, Lara Bollmann, Sigrid Karrer, Mark Berneburg, Sebastian Haferkamp, Dennis Niebel
Publikováno v:
Biology, Vol 13, Iss 7, p 529 (2024)
(1) Background: Rare skin cancers include epithelial, neuroendocrine, and hematopoietic neoplasias as well as cutaneous sarcomas. Ultraviolet (UV) radiation and sunburns are important drivers for the incidence of certain cutaneous sarcomas; however,
Externí odkaz:
https://doaj.org/article/0a8c6ee3419f43a383e2d95aaff22cfb
Autor:
Dirk Schadendorf, Carola Berking, Lisa Zimmer, Ralf Gutzmer, Alexander Kreuter, Andrea Forschner, Elisabeth Livingstone, Bastian Schilling, Selma Ugurel, Peter Mohr, Jessica Hassel, Patrick Terheyden, Henner Stege, Katharina Kaehler, Sebastian Haferkamp, Friedegund Meier, Claudia Pfoehler, Dirk Debus, Rudolf Herbst, Carmen Loquai, Frank Meiss, Martin Kaatz, Jens Ulrich, Edgar Dippel, Michael Weichenthal, Ulrike Leiter, Markus V Heppt, Michael Sachse, Fabian Ziller, Stephan Grabbe, Georg Lodde, Maximilian Haist, Friederike Rogall, Yuqi Tan, Kai Christian Klespe, Michael Tronnier, Imke von Wasielewski, Felix Kieker, Christopher Gebhardt, Jan Simon
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss Suppl 1 (2023)
Externí odkaz:
https://doaj.org/article/85987b665cf74916884422bf2059f401
Autor:
Dirk Schadendorf, Carola Berking, Jessica C Hassel, Lisa Zimmer, Ralf Gutzmer, Alexander Kreuter, Andrea Forschner, Bastian Schilling, Selma Ugurel, Katharina C Kähler, Peter Mohr, Patrick Terheyden, Felix Kiecker, Henner Stege, Sebastian Haferkamp, Friedegund Meier, Claudia Pfoehler, Dirk Debus, Rudolf Herbst, Carmen Loquai, Frank Meiss, Martin Kaatz, Jens Ulrich, Edgar Dippel, Michael Weichenthal, Axel Hauschild, Ulrike Leiter, Markus V Heppt, Christoffer Gebhardt, Michael Sachse, Fabian Ziller, Stephan Grabbe, Georg Lodde, Maximilian Haist, Friederike Rogall, Yuqi Tan, Imke von Wasielewski, Kai Christian Klespe, Michael Tronnier, Jan Christoph Simon
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss 9 (2023)
Background Adjuvant therapy with immune-checkpoint inhibitors (CPI) or BRAF/MEK-directed targeted therapy (TT) improves recurrence-free survival (RFS) for patients with advanced, BRAFV600-mutant (BRAFmut) resected melanoma. However, 40% of these pati
Externí odkaz:
https://doaj.org/article/b02d789393944e89a582fe64cc6e6ada
Autor:
Konstantin Drexler, Veronika Zenderowski, Laura Schreieder, Kevin Koschitzki, Sigrid Karrer, Mark Berneburg, Sebastian Haferkamp, Dennis Niebel
Publikováno v:
Cancers, Vol 16, Iss 1, p 1 (2023)
(1) Background: Ultraviolet (UV) radiation and sunburns are associated with an increased incidence of acquired nevi and melanomas. However, the data are controversial as to whether chronic UV exposure or high intermittent UV exposure is the major car
Externí odkaz:
https://doaj.org/article/23941cc207e045c291c46a15d275a8c5