Zobrazeno 1 - 10
of 44
pro vyhledávání: '"Sebastian Giese"'
Autor:
Jakob Ankerhold, Sebastian Giese, Philipp Kolb, Andrea Maul-Pavicic, Reinhard E. Voll, Nathalie Göppert, Kevin Ciminski, Clemens Kreutz, Achim Lother, Ulrich Salzer, Wolfgang Bildl, Tim Welsink, Nils G. Morgenthaler, Andrea Busse Grawitz, Florian Emmerich, Daniel Steinmann, Daniela Huzly, Martin Schwemmle, Hartmut Hengel, Valeria Falcone
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-15 (2022)
During viral infections high levels of antibodies can form soluble immune complexes (sICs) with antigen and trigger Fcγ receptors (FcγR) leading to increased immunopathology. Here the authors measure FcγRs activation by sICs and consider how these
Externí odkaz:
https://doaj.org/article/a9d748cc00644a7f80d5d264a6b23e8f
Autor:
Matthias Reinscheid, Hendrik Luxenburger, Vivien Karl, Anne Graeser, Sebastian Giese, Kevin Ciminski, David B. Reeg, Valerie Oberhardt, Natascha Roehlen, Julia Lang-Meli, Kathrin Heim, Nina Gross, Christina Baum, Siegbert Rieg, Claudius Speer, Florian Emmerich, Susanne Breisinger, Daniel Steinmann, Bertram Bengsch, Tobias Boettler, Georg Kochs, Martin Schwemmle, Robert Thimme, Christoph Neumann-Haefelin, Maike Hofmann
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-11 (2022)
Vaccines induce beneficial immunity for COVID-19, but immune waning prompts boosting vaccination. Here, the authors show that a third, boosting dose of COVID-19 mRNA vaccine induces transient CD8 + T effector cell response while conserving the CD8 me
Externí odkaz:
https://doaj.org/article/fca8aca08c224586bb686b0fe9b5ffd3
Autor:
Wei Ran, Jacob Schön, Kevin Ciminski, Julian Kraft, Susanne Kessler, Sophie Euchner, Donata Hoffmann, Anne Pohlmann, Martin Beer, Martin Schwemmle, Sebastian Giese
Publikováno v:
Microbiology Spectrum, Vol 10, Iss 6 (2022)
ABSTRACT Recurring epizootic influenza A virus (IAV) infections in domestic livestock such as swine and poultry are associated with a substantial economic burden and pose a constant threat to human health. Therefore, universally applicable and safe a
Externí odkaz:
https://doaj.org/article/6918b7c821674090baccdbde657f2fc1
Autor:
Sebastian Giese, Kevin Ciminski, Hardin Bolte, Étori Aguiar Moreira, Seema Lakdawala, Zehan Hu, Quinnlan David, Larissa Kolesnikova, Veronika Götz, Yongxu Zhao, Jörn Dengjel, Y. Eugene Chin, Ke Xu, Martin Schwemmle
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-11 (2017)
Post-translational modifications of influenza A virus proteins can regulate virus replication, but the effect of nucleoprotein (NP) acetylation is not known. Here, Giese et al. identify four NP lysine residues that are acetylated in infected cells an
Externí odkaz:
https://doaj.org/article/6ed0845914b74bd29b55b944319e9373
Autor:
Étori Aguiar Moreira, Anna Weber, Hardin Bolte, Larissa Kolesnikova, Sebastian Giese, Seema Lakdawala, Martin Beer, Gert Zimmer, Adolfo García-Sastre, Martin Schwemmle, Mindaugas Juozapaitis
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-11 (2016)
The nucleotide sequence of the eight genomic RNA segments of influenza A virus provides essential packaging signals, but how these sequences are recognized is unknown. Here, Moreira et al. identify conserved amino acids in the viral nucleoprotein tha
Externí odkaz:
https://doaj.org/article/fd2af3891b1d4a18955cefaa09570b16
Publikováno v:
Viruses, Vol 12, Iss 4, p 459 (2020)
Bone Marrow Stromal Cell Antigen 2 (BST-2)/tetherin inhibits the release of numerous enveloped viruses by physically tethering nascent particles to infected cells during the process of viral budding from the cell surface. Tetherin also restricts huma
Externí odkaz:
https://doaj.org/article/3fc19e89ca4e48078b2f0a21ccdbbf45
Autor:
Dominik Dornfeld, Alexandra H. Dudek, Thibaut Vausselin, Sira C. Günther, Judd F. Hultquist, Sebastian Giese, Daria Khokhlova-Cubberley, Yap C. Chew, Lars Pache, Nevan J. Krogan, Adolfo Garcia-Sastre, Martin Schwemmle, Megan L. Shaw
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-1 (2018)
A correction to this article has been published and is linked from the HTML and PDF versions of this paper. The error has been fixed in the paper.
Externí odkaz:
https://doaj.org/article/4603d60d7f0c49f29c21c17e19fce69f
Autor:
Sebastian Giese, Mark Marsh
Publikováno v:
PLoS Pathogens, Vol 10, Iss 7, p e1004189 (2014)
Bst-2/Tetherin inhibits the release of HIV by tethering newly formed virus particles to the plasma membrane of infected cells. Although the mechanisms of Tetherin-mediated restriction are increasingly well understood, the biological relevance of this
Externí odkaz:
https://doaj.org/article/ddc6f9405a9f4d93a5740c49a8efb997
Publikováno v:
Viruses, Vol 8, Iss 6, p 165 (2016)
Influenza A viruses (IAVs) harbor a segmented RNA genome that is organized into eight distinct viral ribonucleoprotein (vRNP) complexes. Although a segmented genome may be a major advantage to adapt to new host environments, it comes at the cost of a
Externí odkaz:
https://doaj.org/article/b3216f52edc24f10b0002287a864c0ae
Publikováno v:
Medical Microbiology and Immunology. 212:185-191
Infection with the pandemic human coronavirus SARS-CoV-2 elicits a respiratory tract disease, termed Coronavirus disease 2019 (COVID-19). While a variable degree of disease-associated symptoms may emerge, severe COVID-19 is commonly associated with r