Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Sebastian G Kurz"'
Autor:
Khalid M. Dousa, Eunjeong Shin, Sebastian G. Kurz, Mark Plummer, Mary Nantongo, Christopher R. Bethel, Magdalena A. Taracila, David C. Nguyen, Barry N. Kreiswith, Charles L. Daley, Kenneth E. Remy, Steven M. Holland, Robert A. Bonomo
Publikováno v:
mBio, Vol 15, Iss 6 (2024)
ABSTRACT Mycobacterium abscessus (Mab) affects patients with immunosuppression or underlying structural lung diseases such as cystic fibrosis (CF). Additionally, Mab poses clinical challenges due to its resistance to multiple antibiotics. Herein, we
Externí odkaz:
https://doaj.org/article/fa9a808cd6454120a8ebb14d852179cd
Autor:
Khalid M. Dousa, David C. Nguyen, Sebastian G. Kurz, Magdalena A. Taracila, Christopher R. Bethel, William Schinabeck, Barry N. Kreiswirth, Sheldon T. Brown, W. Henry Boom, Richard S. Hotchkiss, Kenneth E. Remy, Frank J. Jacono, Charles L. Daley, Steven M. Holland, Alita A. Miller, Robert A. Bonomo
Publikováno v:
mBio, Vol 13, Iss 1 (2022)
ABSTRACT Mycobacterium abscessus (Mab) infections are a growing menace to the health of many patients, especially those suffering from structural lung disease and cystic fibrosis. With multidrug resistance a common feature and a growing understanding
Externí odkaz:
https://doaj.org/article/89354fdd37e14eba94df814fcd3ea960
Autor:
Mayanka Tickoo, Robin Ruthazer, Amit Bardia, Shira Doron, Gabriela M. Andujar-Vazquez, Bradley J. Gardiner, David R. Snydman, Sebastian G. Kurz
Publikováno v:
BMC Pulmonary Medicine, Vol 19, Iss 1, Pp 1-7 (2019)
Abstract Background Despite well-defined criteria for use of antibiotics in patients presenting with mild to moderate Acute Exacerbation of Chronic Obstructive Pulmonary Disease (AECOPD), their overuse is widespread. We hypothesized that following im
Externí odkaz:
https://doaj.org/article/ffbbd8fd6ccc480bbbe2e15678709551
Autor:
David C Nguyen, Sarah N Redmond, Khalid M Dousa, Christopher Bethel, Magdalena A Taracila, Qing Li, Sebastian G Kurz, Martin S Pavelka, Krisztina Papp-Wallace, Steven M Holland, Barry N Kreiswirth, Henry Boom, Robert A Bonomo
Publikováno v:
Open Forum Infectious Diseases. 9
Background Drug-resistant tuberculosis (DR TB) is a deadly, difficult-to-treat infection, and new treatment strategies are needed. Despite the wide success of β-lactams (BLs), DR TB guidelines only include meropenem (MEM) and imipenem (IPM), given w
Publikováno v:
Infectious Disease Clinics of North America. 34:863-886
Multidrug-resistant Mycobacterium tuberculosis remains a major public health threat; its management poses a significant economic burden. Treatment requires a programmatic approach with access to laboratory services, second-line medications, and adequ
Autor:
Sebastian G. Kurz, Bradley J. Gardiner, Mayanka Tickoo, Amit Bardia, David R. Snydman, Robin Ruthazer, Gabriela M. Andujar-Vazquez, Shira Doron
Publikováno v:
BMC Pulmonary Medicine, Vol 19, Iss 1, Pp 1-7 (2019)
BMC Pulmonary Medicine
BMC Pulmonary Medicine
Background Despite well-defined criteria for use of antibiotics in patients presenting with mild to moderate Acute Exacerbation of Chronic Obstructive Pulmonary Disease (AECOPD), their overuse is widespread. We hypothesized that following implementat
Autor:
Charles L. Daley, W. Henry Boom, Barry N. Kreiswirth, Khalid M Dousa, Steven M. Holland, George L. Drusano, Robert A. Bonomo, David C Nguyen, Sheldon T. Brown, Sebastian G. Kurz
Publikováno v:
Clin Infect Dis
Mycobacterium abscessus subsp. abscessus is one of the most difficult pathogens to treat and its incidence in disease is increasing. Dual β-lactam combinations act synergistically in vitro but are not widely employed in practice. A recent study show
Publikováno v:
Infectious disease clinics of North America. 34(4)
Multidrug-resistant Mycobacterium tuberculosis remains a major public health threat; its management poses a significant economic burden. Treatment requires a programmatic approach with access to laboratory services, second-line medications, and adequ
Autor:
Michael Holt, Sebastian G. Kurz, B Shoshana Zha, Derrick D. Herman, Charles L. Daley, Joseph K. Ruminjo, Carey C. Thomson
Publikováno v:
Annals of the American Thoracic Society. 17(9)
Autor:
Suresh Selvaraju, Barry N. Kreiswirth, Magdalena A. Taracila, Melissa D. Barnes, Tracey L. Bonfield, Charles L. Daley, Sebastian G. Kurz, Robert A. Bonomo, Khalid M Dousa, W. Henry Boom, Ayman M. Abdelhamed, Christopher R. Bethel, Shannon H. Kasperbauer
Publikováno v:
Antimicrobial Agents and Chemotherapy. 64
Mycobacterium abscessus is a highly drug-resistant nontuberculous mycobacterium (NTM). Efforts to discover new treatments for M. abscessus infections are accelerating, with a focus on cell wall synthesis proteins (M. abscessusl,d-transpeptidases 1 to