Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Sebastian Froehler"'
Autor:
John Jiang, Hans-Peter Adams, Maria Lange, Sandra Siemann, Mirjam Feldkamp, Sylvie McNamara, Sebastian Froehler, Stephanie J. Yaung, Lijing Yao, Aarthi Balasubramanyam, Nalin Tikoo, Christine Ju, H. Jost Achenbach, Rainer Krügel, John F. Palma
Publikováno v:
BMC Cancer, Vol 20, Iss 1, Pp 1-9 (2020)
Abstract Background Identifying and tracking somatic mutations in cell-free DNA (cfDNA) by next-generation sequencing (NGS) has the potential to transform the clinical management of subjects with advanced non-small cell lung cancer (NSCLC). Methods B
Externí odkaz:
https://doaj.org/article/7c0141af1f55427e920f846c74cd2dfa
Autor:
Franz Rüschendorf, Sylvia Bähring, Maolian Gong, Junqing Liang, Lei Zhao, Friedrich C. Luft, Sebastian Froehler, Shuilong Wu, Giannino Patone, Feng Yufei, Guoan Li, Jingjing Zhang, Xiulan Su, Wei Chen, Hongwei Cui, Hao Hu, Liang Fang, Khalid Hussain, Sofia Rahman, Oliver Hummel, Klemens Raile, Yong Yu, Qinghua Chen
Publikováno v:
Journal of Genetics and Genomics. 47:618-626
Congenital hearing loss is a common disorder worldwide. Heterogeneous gene variation accounts for approximately 20-25% of such patients. We investigated a five-generation Chinese family with autosomal-dominant nonsyndromic sensorineural hearing loss
Autor:
Aarthi Balasubramanyam, Sebastian Froehler, Ralph Floegel, H. Jost Achenbach, Rainer Krügel, Alexander F. Lovejoy, Lijing Yao, Frederike Fuhlbrück, Li Tai Fang, Hans-Peter Adams, Nalin Tikoo, John Jiang, John F. Palma, Stephanie J. Yaung, Preeti Lal
Publikováno v:
The Journal of Molecular Diagnostics. 22:228-235
Molecular biomarkers hold promise for personalization of cancer treatment. However, a typical tumor biopsy may be difficult to acquire and may not capture genetic variations within or across tumors. Given these limitations, tumor genotyping using nex
Autor:
Shiqi Jia, Khalid Hussain, Sebastian Froehler, Peter Kuehnen, Lei Liang, Maolian Gong, Philipp Du Bois, Wei Chen, Klemens Raile, Jens Fielitz, Yong Yu, Dogus Vuralli, Jingjing Zhang, Yuantao Liu, Aidi Cao
Publikováno v:
Molecular Genetics & Genomic Medicine
Background Studying patients with rare Mendelian diabetes has uncovered molecular mechanisms regulating β‐cell pathophysiology. Previous studies have shown that Class IIa histone deacetylases (HDAC4, 5, 7, and 9) modulate mammalian pancreatic endo
Autor:
S. Schulze, H.J. Achenbach, Sebastian Froehler, R. Krügel, Aarthi Balasubramanyam, Maria Lange, Mirjam Feldkamp, John Jiang, Sandra Siemann, A. Rosenthal, Stephanie J. Yaung, John F. Palma, Lijing Yao, Nalin Tikoo, Hans-Peter Adams
Publikováno v:
Journal of Thoracic Oncology. 12:S1772-S1773
Autor:
Peter Ebert, Jieyi Xiong, Baerbel Felder, Fatemeh Behjati Ardakani, Barbara Hutter, Matthias Barann, Kathrin Gianmoena, Benedikt Brors, Marcel H. Schulz, Wei Chen, Jörn Walter, Philip Rosenstiel, Azim Dehghani Amirabad, Jan G. Hengstler, Alf Hamann, Jürgen Eils, Anupam Sinha, Karl Nordström, Thomas Lengauer, Gideon Zipprich, Florian Schmidt, Julia K. Polansky, Nina Gasparoni, Gilles Gasparoni, Sebastian Froehler, Cristina Cadenas
Publikováno v:
Nucleic Acids Research
Nucleic acids research, 45(1):54–66
Nucleic acids research, 45(1):54–66
The binding and contribution of transcription factors (TF) to cell specific gene expression is often deduced from open-chromatin measurements to avoid costly TF ChIP-seq assays. Thus, it is important to develop computational methods for accurate TF b
Autor:
H.-P. Adams, Sylvie McNamara, Fjf Herth, Michael Thomas, Stephanie J. Yaung, Xiaoju Max Ma, B. Hinzmann, Felix Lasitschka, Corinna Woestmann, Sebastian Froehler, Thomas Muley, John F. Palma, Liu Xi, Michael Meister, Aarthi Balasubramanyam, Birgit Wehnl, Marc A. Schneider, Nalin Tikoo, Christine Ju
Publikováno v:
Annals of Oncology. 29:viii54
Autor:
B. Hinzmann, Thomas Muley, Arne Warth, Sebastian Froehler, Maria Lange, Michael Meister, A. Rosenthal, Birgit Wehnl, Fjf Herth, Corinna Woestmann, John F. Palma, Marc A Schneider, Michael Thomas, S. Beckert
Publikováno v:
Journal of Thoracic Oncology. 12:S2047
Autor:
Maria Lange, Sandra Siemann, Fergal Casey, Stephanie J. Yaung, Nabil Azhar, John F. Palma, Aruna Arcot, Sophie Beckert, Melissa Loyzer, Alex Lovejoy, Shelly R. Gunn, Sebastian Froehler, William Chiu, Dan Klass
Publikováno v:
Cancer Research. 77:2744-2744
The combination of liquid biopsies and ultra-sensitive next-generation sequencing (NGS) holds tremendous promise in oncology for the detection and surveillance of somatic mutations that correlate with diagnosis, prognosis, response prediction, resist
Publikováno v:
BMC Genomics
Background Exome sequencing is increasingly used to search for phenotypically-relevant sequence variants in the mouse genome. All of the current hybridization-based mouse exome capture systems are designed based on the genome reference sequences of t