Zobrazeno 1 - 10 of 24 pro vyhledávání: '"Sebastian Dorin Asaftei"'
1
Akademický článek
Prolonged 14-day continuous infusion of high-dose ifosfamide for patients with relapsed and refractory high-grade osteosarcoma: a retrospective multicentre cohort study
Autor: Elisa Tirtei, Anna Campello, Veronica Sciannameo, Sebastian Dorin Asaftei, Cristina Meazza, Giovanna Sironi, Alessandra Longhi, Toni Ibrahim, Angela Tamburini, Luca Coccoli, Fanj Crocco, Celeste Cagnazzo, Elvira De Luna, Paola Quarello, Paola Berchialla, Franca Fagioli
Publikováno v: BMC Cancer, Vol 24, Iss 1, Pp 1-12 (2024)
Abstract Background The prognosis of patients with Relapsed/Refractory Osteosarcoma (R/R OS) remains dismal without an agreement on systemic therapy. The use of High-Dose Ifosfamide (14 g/sqm) with an external pump in outpatient setting (14-IFO) in R
Externí odkaz: https://doaj.org/article/6c25b27ede654145b8cb5bdc6877b00e
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2
Akademický článek
Impaired neutrophil-mediated cell death drives Ewing’s Sarcoma in the background of Down syndrome
Autor: Serena Peirone, Elisa Tirtei, Anna Campello, Caterina Parlato, Simonetta Guarrera, Katia Mareschi, Elena Marini, Sebastian Dorin Asaftei, Luca Bertero, Mauro Papotti, Francesca Priante, Sarah Perrone, Matteo Cereda, Franca Fagioli
Publikováno v: Frontiers in Oncology, Vol 14 (2024)
IntroductionEwing Sarcoma (EWS) has been reported in seven children with Down syndrome (DS). To date, a detailed assessment of this solid tumour in DS patients is yet to be made.MethodsHere, we characterise a chemo-resistant mediastinal EWS in a 2-ye
Externí odkaz: https://doaj.org/article/4b2a693d4f284bb7855d8b37a744d990
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3
Akademický článek
The exposure to extremely low frequency electromagnetic-fields inhibits the growth and potentiates the sensitivity to chemotherapy of bidimensional and tridimensional human osteosarcoma models
Autor: Umberto Lucia, Loredana Bergandi, Giulia Grisolia, Debora Fino, Katia Mareschi, Elena Marini, Alessia Giovanna Santa Banche Niclot, Elisa Tirtei, Sebastian Dorin Asaftei, Franca Fagioli, Antonio Ponzetto, Francesca Silvagno
Publikováno v: Biomedicine & Pharmacotherapy, Vol 177, Iss , Pp 117162- (2024)
We previously established a thermodynamical model to calculate the specific frequencies of extremely low frequency-electromagnetic field (ELF-EMF) able to arrest the growth of cancer cells. In the present study, for the first time, we investigated th
Externí odkaz: https://doaj.org/article/c094750c0fb143af82f33bafc872fa76
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4
Akademický článek
An integrative morpho-molecular approach in malignant ectomesenchymoma diagnosis: report of a new paediatric case and a review of the literature
Autor: Francesco Pellegrino, Elisa Tirtei, Federico Divincenzo, Anna Campello, Carlotta Rubino, Elisabetta Augustoni, Alessandra Linari, Sebastian Dorin Asaftei, Franca Fagioli
Publikováno v: Frontiers in Oncology, Vol 14 (2024)
IntroductionMalignant ectomesenchymoma (MEM) is a soft tissue tumour, consisting of both malignant neuroectodermal elements and one or more mesenchymal elements.Case presentation and review of the literatureHere we describe the case of a 6-months-old
Externí odkaz: https://doaj.org/article/fdbb20f0c0a8451ba40a9f24bc0a224f
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5
Impaired neutrophil-mediated cell death drives Ewing's Sarcoma in a two years old child with Down Syndrome
Autor: Serena Peirone, Elisa Tirtei, Anna Campello, Caterina Parlato, Simonetta Guarrera, Katia Mareschi, Elena Marini, Sebastian Dorin Asaftei, Luca Bertero, Mauro Papotti, Matteo Cereda, Franca Fagioli
Ewing's Sarcoma (EWS) has been reported in seven children with Down Syndrome (DS). To date, a detailed assessment of this solid tumor in DS patients is still missing. Here, we characterized a chemo-resistant mediastinal EWS in a 2-year-old DS child,
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::6c9f78269f3ef13e8df84f225eaf1037
https://doi.org/10.1101/2023.05.30.23289664
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6
State-of-the-art, approved therapeutics for the pharmacological management of osteosarcoma
Autor: Cristina Meazza, Sebastian Dorin Asaftei
Publikováno v: Expert opinion on pharmacotherapy. 22(15)
Introduction Advances in the treatment of osteosarcoma (OS) came in the mid-1970s, when adding chemotherapy to surgery significantly improved patient survival. OS outcomes have since plateaued, however, despite exhaustive clinical investigations. Are
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bec90056b91d08f5c8bef286e14bf428
https://pubmed.ncbi.nlm.nih.gov/34058096
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9
Gemcitabine-docetaxel in patients with relapsed high-grade osteosarcoma after first-line treatment with high-dose ifosfamide: A retrospective multicenter study
Autor: Maria Grazia Pionelli, Sebastian Dorin Asaftei, Cristina Meazza, Alessandra Longhi, Angela Tamburini, Luca Coccoli, Alessandra Merlini, Celeste Cagnazzo, Tirtei Tirtei, Franca Fagioli
Publikováno v: Journal of Clinical Oncology. 40:11520-11520
11520 Background: Currently, there is no accepted standard chemotherapy regimen for recurrent osteosarcoma. We performed a retrospective study to evaluate the effectiveness, toxicity and clinical benefit of second line therapy with Gemcitabine (G) in
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::5b015ae661814c1c17902e1f3ac0ecab
https://doi.org/10.1200/jco.2022.40.16_suppl.11520
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10
Precision Medicine in Osteosarcoma: MATCH Trial and Beyond
Autor: Franca Fagioli, Anna Campello, Sebastian Dorin Asaftei, Elisa Tirtei, Matteo Cereda, Katia Mareschi
Publikováno v: Cells
Cells, Vol 10, Iss 281, p 281 (2021)
Osteosarcoma (OS) is a rare bone malignant tumour with a poor prognosis in the case of recurrence. So far, there is no agreement on the best systemic therapy for relapsed OS. The availability of next generation sequencing techniques has recently revo
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ea6aa17933ce7a386093d30d93be8b5
https://pubmed.ncbi.nlm.nih.gov/33572496
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