Výsledky vyhledávání - "Sebastian Darr"

Phylogeny and primary structure analysis of fiber shafts of all human adenovirus types for rational design of adenoviral gene-therapy vectors

Autor: Albert Heim, Fabienne Rehren, Soren Hofmayer, Sebastian Darr, Ijad Madisch

Publikováno v: Journal of General Virology. 90:2849-2854

The fiber shaft of human adenoviruses (HAdVs) is essential for bringing the penton base into proximity to the secondary cellular receptor. Fiber shaft sequences of all 53 HAdV types were studied. Phylogeny of the fiber shaft revealed clustering corre

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::036c5fcbb57a1e8a540f60e908bc5bd7
https://doi.org/10.1099/vir.0.014514-0

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Type dependent patterns of human adenovirus persistence in human T-lymphocyte cell lines

Autor: Dominik, Markel, Elena, Lam, Gabriele, Harste, Sebastian, Darr, Mirja, Ramke, Albert, Heim

Publikováno v: Journal of medical virology. 86(5)

Disseminated adenovirus infections cause significant mortality in stem cell transplanted patients and are suspected to originate from asymptomatic adenovirus persistence ("latency") in lymphocytes. The infection of three human T-lymphocyte lines (Jur

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::f293cd39ff6f428a6345f8e6b02f36e1
https://pubmed.ncbi.nlm.nih.gov/24026974

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Tripeptidyl Peptidase II Is Required for c-MYC–Induced Centriole Overduplication and a Novel Therapeutic Target in c-MYC–Associated Neoplasms

Autor: Stefan Duensing, Nadja V. Melquiot, Sebastian Darr, Anette Duensing, Rolando A. Cuevas, Karl Münger, Anthony G. Brickner

Centrosome aberrations are frequently detected in c-MYC-associated human malignancies. Here, we show that c-MYC-induced centrosome and centriole overduplication critically depend on the protease tripeptidyl peptidase II (TPPII). We found that TPPII l

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::29cd92ebd5d88ad3e4b55622da48bd34
https://europepmc.org/articles/PMC3092256/

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Unique sequence features of the Human Adenovirus 31 complete genomic sequence are conserved in clinical isolates

Autor: Albert Heim, Soeren Hofmayer, Fabienne Rehren, Sebastian Darr, Ijad Madisch

Publikováno v: BMC Genomics, Vol 10, Iss 1, p 557 (2009)
BMC Genomics

Background Human adenoviruses (HAdV) are causing a broad spectrum of diseases. One of the most severe forms of adenovirus infection is a disseminated disease resulting in significant morbidity and mortality. Several reports in recent years have ident

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a5d962f75e2911640cfa7ab8ff507fc
https://doi.org/10.1186/1471-2164-10-557

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Antiviral activity of cidofovir and ribavirin against the new human adenovirus subtype 14a that is associated with severe pneumonia

Autor: Ijad Madisch, Sebastian Darr, Albert Heim

Publikováno v: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America. 47(5)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0083fde2c2ce94eff68dd9e6b7fe439e
https://pubmed.ncbi.nlm.nih.gov/18173356

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