Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Sebastian C Holst"'
Autor:
Henrik Zetterberg, Kaj Blennow, José Luis Molinuevo, Andreea Radoi, Carolina Minguillón, Karine Fauria, Carme Deulofeu, Marc Suárez-Calvet, Oriol Grau-Rivera, Alex Iranzo, Iva Knezevic, Núria Tort-Colet, Laura Stankeviciute, Laura Hernández, Sherezade Fuentes-Julián, Israel Turull, David Fusté, Gonzalo Sánchez-Benavides, Eider M Arenaza-Urquijo, Sebastian C Holst, Pilar Garcés, Thomas Mueggler, Aurora Arqueros, Juan Domingo Gispert
Publikováno v:
BMJ Open, Vol 12, Iss 12 (2022)
Introduction The growing worldwide prevalence of Alzheimer’s disease (AD) and the lack of effective treatments pose a dire medical challenge. Sleep disruption is also prevalent in the ageing population and is increasingly recognised as a risk facto
Externí odkaz:
https://doaj.org/article/c793807a0174443da3ac6afb35420871
Autor:
Sebastian C Holst, Alexandra Sousek, Katharina Hefti, Sohrab Saberi-Moghadam, Alfred Buck, Simon M Ametamey, Milan Scheidegger, Paul Franken, Anke Henning, Erich Seifritz, Mehdi Tafti, Hans-Peter Landolt
Publikováno v:
eLife, Vol 6 (2017)
Increased sleep time and intensity quantified as low-frequency brain electrical activity after sleep loss demonstrate that sleep need is homeostatically regulated, yet the underlying molecular mechanisms remain elusive. We here demonstrate that metab
Externí odkaz:
https://doaj.org/article/827159348a494799a89ae5068a6fd19c
Autor:
Congying Chu, Sebastian C. Holst, Eva-Maria Elmenhorst, Anna L. Foerges, Changhong Li, Denise Lange, Eva Hennecke, Diego M. Baur, Simone Beer, Felix Hoffstaedter, Gitte M. Knudsen, Daniel Aeschbach, Andreas Bauer, Hans-Peter Landolt, David Elmenhorst
Publikováno v:
The Journal of Neuroscience. 43:2168-2177
Sleep loss pervasively affects the human brain at multiple levels. Age-related changes in several sleep characteristics indicate that reduced sleep quality is a frequent characteristic of aging. Conversely, sleep disruption may accelerate the aging p
Autor:
Hans-Peter Landolt, Sebastian C. Holst
Publikováno v:
Sleep Medicine Clinics. 17:151-160
Behavioral states naturally alternate between wakefulness and the sleep phases rapid eye movement and nonrapid eye movement sleep. Waking and sleep states are complex processes that are elegantly orchestrated by spatially fine-tuned neurochemical cha
Autor:
Hubert Banville, Maurice Abou Jaoude, Sean U.N. Wood, Chris Aimone, Sebastian C. Holst, Alexandre Gramfort, Denis-Alexander Engemann
Publikováno v:
bioRxiv
EEG is an established method for quantifying large-scale neuronal dynamics which enables diverse real-world biomedical applications including brain-computer interfaces, epilepsy monitoring and sleep staging. Advances in sensor technology have freed E
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::58275d0ad522812c70e802cf6bb27cd7
https://doi.org/10.1101/2023.04.29.538328
https://doi.org/10.1101/2023.04.29.538328
Autor:
Karine Fauria, Carolina Minguillon, Iva Knezevic, Núria Tort-Colet, Laura Stankeviciute, Laura Hernández, Andreea Rădoi, Carme Deulofeu, Sherezade Fuentes-Julián, Israel Turull, David Fusté, Gonzalo Sánchez-Benavides, Eider M Arenaza-Urquijo, Marc Suárez-Calvet, Sebastian C Holst, Pilar Garcés, Thomas Mueggler, Henrik Zetterberg, Kaj Blennow, Aurora Arqueros, Álex Iranzo, Juan Domingo Gispert, José Luis Molinuevo, Oriol Grau-Rivera
Publikováno v:
BMJ open. 12(12)
Introduction: the growing worldwide prevalence of Alzheimer's disease (AD) and the lack of effective treatments pose a dire medical challenge. Sleep disruption is also prevalent in the ageing population and is increasingly recognised as a risk factor
Autor:
Tomas Bohr, Poul G. Hjorth, Sebastian C. Holst, Sabina Hrabětová, Vesa Kiviniemi, Tuomas Lilius, Iben Lundgaard, Kent-Andre Mardal, Erik A. Martens, Yuki Mori, U. Valentin Nägerl, Charles Nicholson, Allen Tannenbaum, John H. Thomas, Jeffrey Tithof, Helene Benveniste, Jeffrey J. Iliff, Douglas H. Kelley, Maiken Nedergaard
Publikováno v:
Bohr, T, Hjorth, P G, Holst, S C, Hrabětová, S, Kiviniemi, V, Lilius, T, Lundgaard, I, Mardal, K A, Martens, E A, Mori, Y, Nägerl, U V, Nicholson, C, Tannenbaum, A, Thomas, J H, Tithof, J, Benveniste, H, Iliff, J J, Kelley, D H & Nedergaard, M 2022, ' The glymphatic system : Current understanding and modeling ', iScience, vol. 25, no. 9, 104987 . https://doi.org/10.1016/j.isci.2022.104987
We review theoretical and numerical models of the glymphatic system, which circulates cerebrospinal fluid and interstitial fluid around the brain, facilitating solute transport. Models enable hypothesis development and predictions of transport, with
Autor:
Heta, Helakari, Vesa, Korhonen, Sebastian C, Holst, Johanna, Piispala, Mika, Kallio, Tommi, Väyrynen, Niko, Huotari, Lauri, Raitamaa, Johanna, Tuunanen, Janne, Kananen, Matti, Järvelä, Timo, Tuovinen, Ville, Raatikainen, Viola, Borchardt, Hannu, Kinnunen, Maiken, Nedergaard, Vesa, Kiviniemi
Publikováno v:
The Journal of neuroscience : the official journal of the Society for Neuroscience. 42(12)
The physiological underpinnings of the necessity of sleep remain uncertain. Recent evidence suggests that sleep increases the convection of cerebrospinal fluid (CSF) and promotes the export of interstitial solutes, thus providing a framework to expla
Publikováno v:
Praxis. 108:131-138
Zusammenfassung. Schlaf ist ein komplexes Verhalten, das von verschiedenen Kerngebieten im Gehirn koordiniert wird. Diese neurochemischen Systeme modulieren die Wachheit und den Schlaf und können pharmakologisch beeinflusst werden. Die exzessive Tag
Autor:
Zalán Rajna, Heli Mattila, Niko Huotari, Timo Tuovinen, Johanna Krüger, Sebastian C Holst, Vesa Korhonen, Anne M Remes, Tapio Seppänen, Jürgen Hennig, Maiken Nedergaard, Vesa Kiviniemi
Publikováno v:
Brain
Accumulation of amyloid-β is a key neuropathological feature in brain of Alzheimer’s disease patients. Alterations in cerebral haemodynamics, such as arterial impulse propagation driving the (peri)vascular CSF flux, predict future Alzheimer’s di
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::79c07923f100e33904f2b1abd2e64412
http://urn.fi/urn:nbn:fi-fe2021083044614
http://urn.fi/urn:nbn:fi-fe2021083044614