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pro vyhledávání: '"Sebastian Brzozy"'
Autor:
Giovanna Tripepi, Ruth Farmer, Salman Haider, Monika Rudzińska, G Westerberg, Sebastian Brzozy, Karin Schiefele, Elisa Mori, Letizia Magnoni, Michael Orth, Sarah J. Tabrizi, Ralph Andre, Marco Di Bacco, Carsten Saft, Danuta Ryglewicz, Giuseppe Pollio, Daniela Diamanti, Chris Frost, Claus A. Andersen, Sigurd D. Süssmuth, Enrica Diodato, Luisa Massai, Jens Dreyhaupt, Claudia Lamanna, Anna Baran, Borje Darpo, David Craufurd, G. Bernhard Landwehrmeyer
Publikováno v:
British Journal of Clinical Pharmacology. 79:465-476
AIMS: Selisistat, a selective SirT1 inhibitor is being developed as a potentially disease-modifying therapeutic for Huntington's disease (HD). This was the first study of selisistat in HD patients and was primarily aimed at development of pharmacodyn