Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Sebastian Bruchmann"'
Autor:
Francesc Coll, Theodore Gouliouris, Sebastian Bruchmann, Jody Phelan, Kathy E. Raven, Taane G. Clark, Julian Parkhill, Sharon J. Peacock
Publikováno v:
Communications Biology, Vol 5, Iss 1, Pp 1-12 (2022)
PowerBacGWAS is a computational pipeline that uses existing genomic data to perform power calculations for bacterial genome-wide association studies.
Externí odkaz:
https://doaj.org/article/2972363566b540349ada2c5140fdbb7a
Autor:
Gemma G. R. Murray, Andrew J. Balmer, Josephine Herbert, Nazreen F. Hadjirin, Caroline L. Kemp, Marta Matuszewska, Sebastian Bruchmann, A. S. Md. Mukarram Hossain, Marcelo Gottschalk, Alexander W. Tucker, Eric Miller, Lucy A. Weinert
Publikováno v:
PLoS Genetics, Vol 17, Iss 11 (2021)
Mutation rates vary both within and between bacterial species, and understanding what drives this variation is essential for understanding the evolutionary dynamics of bacterial populations. In this study, we investigate two factors that are predicte
Externí odkaz:
https://doaj.org/article/c33dbcb5f57e4a9bb55867d0f062883d
Autor:
Sebastian Schulz, Denitsa Eckweiler, Agata Bielecka, Tanja Nicolai, Raimo Franke, Andreas Dötsch, Klaus Hornischer, Sebastian Bruchmann, Juliane Düvel, Susanne Häussler
Publikováno v:
PLoS Pathogens, Vol 11, Iss 3, p e1004744 (2015)
Sigma factors are essential global regulators of transcription initiation in bacteria which confer promoter recognition specificity to the RNA polymerase core enzyme. They provide effective mechanisms for simultaneously regulating expression of large
Externí odkaz:
https://doaj.org/article/b5bb74490e97425a80d6e1d7dbff5f3a
Autor:
Valérie Briolat, Stevenn Volant, Sebastian Bruchmann, Susanne Häussler, Joaquín Bernal-Bayard, Franziska A. Stressmann, Bianca Audrain, Jean-Marc Ghigo, Amine Ghozlane, David Pérez-Pascual, Eric Duchaud, Jean-Pierre Levraud, Olaya Rendueles
Publikováno v:
The ISME Journal
The ISME journal
England
ISME J
ISME Journal
ISME Journal, 2021, 15 (3), pp.702-719. ⟨10.1038/s41396-020-00807-8⟩
ISME Journal, Nature Publishing Group, 2020, 15 (3), pp.702-719. ⟨10.1038/s41396-020-00807-8⟩
The ISME journal
England
ISME J
ISME Journal
ISME Journal, 2021, 15 (3), pp.702-719. ⟨10.1038/s41396-020-00807-8⟩
ISME Journal, Nature Publishing Group, 2020, 15 (3), pp.702-719. ⟨10.1038/s41396-020-00807-8⟩
The long-known resistance to pathogens provided by host-associated microbiota fostered the notion that adding protective bacteria could prevent or attenuate infection. However, the identification of endogenous or exogenous bacteria conferring such pr
Autor:
Josephine Herbert, A. S. Md. Mukarram Hossain, Gemma G. R. Murray, Marta Matuszewska, Lucy A. Weinert, Alexander W. Tucker, Andrew J. Balmer, Marcelo Gottschalk, Sebastian Bruchmann, Nazreen F. Hadjirin, Caroline L. Kemp, Eric L. Miller
Publikováno v:
PLoS Genetics, Vol 17, Iss 11 (2021)
PLoS Genetics, Vol 17, Iss 11, p e1009864 (2021)
PLoS Genetics
PLoS Genetics, Vol 17, Iss 11, p e1009864 (2021)
PLoS Genetics
Funder: Isaac Newton Trust; funder-id: http://dx.doi.org/10.13039/501100004815
Funder: Newnham College, University of Cambridge; funder-id: http://dx.doi.org/10.13039/501100000663
Funder: Biotechnology and Biological Sciences Research Counc
Funder: Newnham College, University of Cambridge; funder-id: http://dx.doi.org/10.13039/501100000663
Funder: Biotechnology and Biological Sciences Research Counc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d228608e857a95997fee11899638f74
https://www.repository.cam.ac.uk/handle/1810/330904
https://www.repository.cam.ac.uk/handle/1810/330904
Autor:
Sarina Bense, Sebastian Bruchmann, Susanne Häussler, Anika Steffen, Juliane Düvel, Theresia E. B. Stradal
Publikováno v:
Molecular microbiology
The c-di-GMP-binding effector protein FlgZ has been demonstrated to control motility in the opportunistic pathogen Pseudomonas aeruginosa and it was suggested that c-di-GMP-bound FlgZ impedes motility via its interaction with the MotCD stator. To fur
Autor:
Andrew J. Balmer, Nazreen F. Hadijirin, Marta Matuszewska, Josephine Herbert, A. S. Md. Mukarram Hossain, Gemma G. R. Murray, Alexander W. Tucker, Caroline L. Kemp, Marcelo Gottschalk, Eric L. Miller, Sebastian Bruchmann, Lucy A. Weinert
While mutation is often deleterious, it can also be adaptive. Mutation rates vary both within and between bacterial species, and understanding what drives this variation is essential for understanding the evolutionary dynamics of bacterial population
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1a01fafc2c47ca9fb1ec8e653881117d
https://doi.org/10.1101/2021.04.12.439332
https://doi.org/10.1101/2021.04.12.439332
Publikováno v:
Pathogens and Disease
Infections caused by Klebsiella pneumoniae are a major public health threat. Extensively drug-resistant and even pan-resistant strains have been reported. Understanding K. pneumoniae pathogenesis is hampered by the fact that murine models of infectio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae7ef0c2491433c0ffc168d51ee80c7f
https://www.repository.cam.ac.uk/handle/1810/319866
https://www.repository.cam.ac.uk/handle/1810/319866
Autor:
Yair Motro, Neil Woodford, Jody Phelan, Jim F. Huggett, Matthew J. Ellington, Denise M. O'Sullivan, Liam P. Shaw, Jacob Moran-Gilad, Taane G. Clark, Martin Cormican, Kathryn A. Harris, Ronan Doyle, Ernest Diez Benavente, Alex van Belkum, Sebastian Bruchmann, Richard A. Stabler, Lucy van Dorp, Sean D Aller, Thi Phuong Thuy Nguyen, Elaine McGrath, Andreu Coello Pelegrin
Publikováno v:
BioRxiv
Microbial Genomics
Microbial Genomics
BackgroundAntimicrobial resistance (AMR) poses a threat to public health. Clinical microbiology laboratories typically rely on culturing bacteria for antimicrobial susceptibility testing (AST). As the implementation costs and technical barriers fall,
Autor:
Marina C. Pils, Laura M. Nolan, Nora Grahl, Matthias Preuße, Susanne Häussler, Siegfried Weiss, Sebastian Bruchmann, Alain Filloux, Vinay Pawar, Anne Lorenz
Publikováno v:
Environmental microbiology
Environmental Microbiology
Environmental Microbiology
Pseudomonas aeruginosa is an environmental microorganism and a causative agent of diverse acute and chronic, biofilm-associated infections. Advancing research-based knowledge on its adaptation to conditions within the human host is bound to reveal no