Zobrazeno 1 - 10
of 34
pro vyhledávání: '"Sebastian Bittrich"'
Publikováno v:
Frontiers in Bioinformatics, Vol 3 (2023)
Recent advances in Artificial Intelligence and Machine Learning (e.g., AlphaFold, RosettaFold, and ESMFold) enable prediction of three-dimensional (3D) protein structures from amino acid sequences alone at accuracies comparable to lower-resolution ex
Externí odkaz:
https://doaj.org/article/996e6411879c41209af17a862968a3cb
Autor:
Sebastian Bittrich, Marika Kaden, Christoph Leberecht, Florian Kaiser, Thomas Villmann, Dirk Labudde
Publikováno v:
BioData Mining, Vol 12, Iss 1, Pp 1-16 (2019)
Abstract Background Machine learning strategies are prominent tools for data analysis. Especially in life sciences, they have become increasingly important to handle the growing datasets collected by the scientific community. Meanwhile, algorithms im
Externí odkaz:
https://doaj.org/article/26ad962439454e4985502b9f6515bafc
Publikováno v:
PLoS Computational Biology, Vol 16, Iss 12, p e1008502 (2020)
Biochemical and biological functions of proteins are the product of both the overall fold of the polypeptide chain, and, typically, structural motifs made up of smaller numbers of amino acids constituting a catalytic center or a binding site that may
Externí odkaz:
https://doaj.org/article/b44d48ecc2444dc8b87154b6c4b5944e
Autor:
David Sehnal, Sebastian Bittrich, Sameer Velankar, Jaroslav Koča, Radka Svobodová, Stephen K Burley, Alexander S Rose
Publikováno v:
PLoS Computational Biology, Vol 16, Iss 10, p e1008247 (2020)
3D macromolecular structural data is growing ever more complex and plentiful in the wake of substantive advances in experimental and computational structure determination methods including macromolecular crystallography, cryo-electron microscopy, and
Externí odkaz:
https://doaj.org/article/313803daed7c480ca2e26869858d8f23
Autor:
Florian Kaiser, Sebastian Bittrich, Sebastian Salentin, Christoph Leberecht, V Joachim Haupt, Sarah Krautwurst, Michael Schroeder, Dirk Labudde
Publikováno v:
PLoS Computational Biology, Vol 14, Iss 4, p e1006101 (2018)
The origin of the machinery that realizes protein biosynthesis in all organisms is still unclear. One key component of this machinery are aminoacyl tRNA synthetases (aaRS), which ligate tRNAs to amino acids while consuming ATP. Sequence analyses reve
Externí odkaz:
https://doaj.org/article/36dba8e9aa13444bba901ec12492f283
Publikováno v:
PLoS ONE, Vol 13, Iss 10, p e0206369 (2018)
Proteins are chains of amino acids which adopt a three-dimensional structure and are then able to catalyze chemical reactions or propagate signals in organisms. Without external influence, many proteins fold into their native structure, and a small n
Externí odkaz:
https://doaj.org/article/2d8a65749aca41c5b5d8482741b24373
Autor:
Stephen K Burley, Charmi Bhikadiya, Chunxiao Bi, Sebastian Bittrich, Henry Chao, Li Chen, Paul A Craig, Gregg V Crichlow, Kenneth Dalenberg, Jose M Duarte, Shuchismita Dutta, Maryam Fayazi, Zukang Feng, Justin W Flatt, Sai Ganesan, Sutapa Ghosh, David S Goodsell, Rachel Kramer Green, Vladimir Guranovic, Jeremy Henry, Brian P Hudson, Igor Khokhriakov, Catherine L Lawson, Yuhe Liang, Robert Lowe, Ezra Peisach, Irina Persikova, Dennis W Piehl, Yana Rose, Andrej Sali, Joan Segura, Monica Sekharan, Chenghua Shao, Brinda Vallat, Maria Voigt, Ben Webb, John D Westbrook, Shamara Whetstone, Jasmine Y Young, Arthur Zalevsky, Christine Zardecki
Publikováno v:
Nucleic Acids Research. 51:D488-D508
The Research Collaboratory for Structural Bioinformatics Protein Data Bank (RCSB PDB), founding member of the Worldwide Protein Data Bank (wwPDB), is the US data center for the open-access PDB archive. As wwPDB-designated Archive Keeper, RCSB PDB is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::504619fca195c6a17681b3527b399ef9
https://doi.org/10.1093/nar/gkac1077
https://doi.org/10.1093/nar/gkac1077
Autor:
Stephen K. Burley, Zukang Feng, John D. Westbrook, Andrej Sali, Justin W Flatt, Rachel Kramer Green, Chenghua Shao, Sai J. Ganesan, Sutapa Ghosh, Brinda Vallat, David S. Goodsell, Jeremy Henry, Christine Zardecki, Joan Segura, Ezra Peisach, Charmi Bhikadiya, Catherine L. Lawson, Jose M. Duarte, Brian P. Hudson, Irina Persikova, Chunxiao Bi, Gregg V. Crichlow, Robert Lowe, Monica Sekharan, Jasmine Young, Shamara Whetstone, Li Chen, Vladimir Guranovic, Yu-He Liang, Dennis W Piehl, Maryam Fayazi, Maria Voigt, Sebastian Bittrich, Shuchismita Dutta, Yana Rose
Publikováno v:
Protein Sci
The Research Collaboratory for Structural Bioinformatics Protein Data Bank (RCSB PDB), funded by the US National Science Foundation, National Institutes of Health, and Department of Energy, has served structural biologists and Protein Data Bank (PDB)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6228c32dd89013c7b715bdae16133fd0
https://doi.org/10.1002/pro.4213
https://doi.org/10.1002/pro.4213
Autor:
Stephen K. Burley, Charmi Bhikadiya, Chunxiao Bi, Sebastian Bittrich, Henry Chao, Li Chen, Paul A. Craig, Gregg V. Crichlow, Kenneth Dalenberg, Jose M. Duarte, Shuchismita Dutta, Maryam Fayazi, Zukang Feng, Justin W. Flatt, Sai J. Ganesan, Sutapa Ghosh, David S. Goodsell, Rachel Kramer Green, Vladimir Guranovic, Jeremy Henry, Brian P. Hudson, Igor Khokhriakov, Catherine L. Lawson, Yuhe Liang, Robert Lowe, Ezra Peisach, Irina Persikova, Dennis W. Piehl, Yana Rose, Andrej Sali, Joan Segura, Monica Sekharan, Chenghua Shao, Brinda Vallat, Maria Voigt, Benjamin Webb, John D. Westbrook, Shamara Whetstone, Jasmine Y. Young, Arthur Zalevsky, Christine Zardecki
Publikováno v:
Protein science : a publication of the Protein Society, vol 31, iss 12
Now in its 52nd year of continuous operations, the Protein Data Bank (PDB) is the premiere open-access global archive housing three-dimensional (3D) biomolecular structure data. It is jointly managed by the Worldwide Protein Data Bank (wwPDB) partner
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::43206e1b074c74262e987e5608f0046a
https://pubmed.ncbi.nlm.nih.gov/36281733
https://pubmed.ncbi.nlm.nih.gov/36281733
Autor:
Sebastian Bittrich, Yana Rose, Joan Segura, Robert Lowe, John D Westbrook, Jose M Duarte, Stephen K Burley
Publikováno v:
Bioinformatics. 38:1452-1454
Motivation Membrane proteins are encoded by approximately one fifth of human genes but account for more than half of all US FDA approved drug targets. Thanks to new technological advances, the number of membrane proteins archived in the PDB is growin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::40a3587448bd50003fe6caef1be1dee8
https://doi.org/10.1093/bioinformatics/btab813
https://doi.org/10.1093/bioinformatics/btab813