Zobrazeno 1 - 10
of 944
pro vyhledávání: '"Sebastian Bauer"'
Autor:
Niraj Khemka, Gareth Morris, Laleh Kazemzadeh, Lara S. Costard, Valentin Neubert, Sebastian Bauer, Felix Rosenow, Morten T. Venø, Jørgen Kjems, David C. Henshall, Jochen H. M. Prehn, Niamh M. C. Connolly
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-16 (2024)
Abstract Epileptogenesis is the process by which a normal brain becomes hyperexcitable and capable of generating spontaneous recurrent seizures. The extensive dysregulation of gene expression associated with epileptogenesis is shaped, in part, by mic
Externí odkaz:
https://doaj.org/article/aec36402be9d4848857dd99eb744d751
Autor:
Celina Tretter, Niklas de Andrade Krätzig, Matteo Pecoraro, Sebastian Lange, Philipp Seifert, Clara von Frankenberg, Johannes Untch, Gabriela Zuleger, Mathias Wilhelm, Daniel P. Zolg, Florian S. Dreyer, Eva Bräunlein, Thomas Engleitner, Sebastian Uhrig, Melanie Boxberg, Katja Steiger, Julia Slotta-Huspenina, Sebastian Ochsenreither, Nikolas von Bubnoff, Sebastian Bauer, Melanie Boerries, Philipp J. Jost, Kristina Schenck, Iska Dresing, Florian Bassermann, Helmut Friess, Daniel Reim, Konrad Grützmann, Katrin Pfütze, Barbara Klink, Evelin Schröck, Bernhard Haller, Bernhard Kuster, Matthias Mann, Wilko Weichert, Stefan Fröhling, Roland Rad, Michael Hiltensperger, Angela M. Krackhardt
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-22 (2023)
Abstract Systemic pan-tumor analyses may reveal the significance of common features implicated in cancer immunogenicity and patient survival. Here, we provide a comprehensive multi-omics data set for 32 patients across 25 tumor types for proteogenomi
Externí odkaz:
https://doaj.org/article/1b677a5e3e974d68b06b73bc60798d1c
Publikováno v:
Geothermal Energy, Vol 11, Iss 1, Pp 1-27 (2023)
Abstract In order to compensate for the variable mismatch between heat demand and heat production from renewable sources or waste heat, high-temperature aquifer thermal energy storage (HT-ATES) is a promising option. A reliable prediction of the ener
Externí odkaz:
https://doaj.org/article/947426ab675340e9a982f213ce17a56a
Autor:
Anna Maria Frezza, Hugh Leonard, Ninna Aggerholm-Pedersen, Giuseppe Badalamenti, Paolo Baili, Giacomo G Baldi, Sebastian Bauer, Serena Bazzurri, Irene Benzonelli, Alexia Bertuzzi, Jean-Yves Blay, Giuseppe Bianchi, Simone Bonfarnuzzo, Christophe Bouvier, Kyetil Boye, Javier Martin Broto, Antonella Brunello, Domenico Campanacci, Paolo G Casali, Carlo Cicala, Elisa Crotti, Lorenzo D'Ambrosio, Angelo Paolo Dei Tos, Nils Dieckmann, Armelle Dufresne, Stephanie Elston, Virginia Ferraresi, Stefano Gabellini, Claudia Giani, Vincenzo Giannusa, Melissa Gil Sanjines, Teresa Grassani, Alessandro Gronchi, Paolo Lasalvia, Stefan Lindskog, Nadia Hindi, Matilde Ingrosso, Andrei Ivanescu, Robin Jones, Iwona Lugowska, Julia Ketzer, Anna Mariuk-Jarema, Alessandro Mazzocca, Laura Monteleone, Carlo Morosi, Andrea Napolitano, Francesca Nardozza, Elisabetta Neri, Maria Nilsson, Andri Papakonstantinou, Sandro Pasquali, Marta Sbaraglia, Federico Scolari, Joanna Szkandera, Claudia Valverde, Bruno Vincenzi, Salvatore Vizzaccaro, Federica Zuccheri, Silvia Stacchiotti, Annalisa Trama
Publikováno v:
PLoS ONE, Vol 19, Iss 8, p e0308387 (2024)
IntroductionEpithelioid hemangioendothelioma (EHE) is an ultra-rare sarcoma, marked by distinctive molecular and pathological features and with a variable clinical behavior. Its natural history is still partially understood, reliable prognostic and p
Externí odkaz:
https://doaj.org/article/437c63f0b21f4d4db2adca8416449656
Autor:
Celina Tretter, Niklas de Andrade Krätzig, Matteo Pecoraro, Sebastian Lange, Philipp Seifert, Clara von Frankenberg, Johannes Untch, Gabriela Zuleger, Mathias Wilhelm, Daniel P. Zolg, Florian S. Dreyer, Eva Bräunlein, Thomas Engleitner, Sebastian Uhrig, Melanie Boxberg, Katja Steiger, Julia Slotta-Huspenina, Sebastian Ochsenreither, Nikolas von Bubnoff, Sebastian Bauer, Melanie Boerries, Philipp J. Jost, Kristina Schenck, Iska Dresing, Florian Bassermann, Helmut Friess, Daniel Reim, Konrad Grützmann, Katrin Pfütze, Barbara Klink, Evelin Schröck, Bernhard Haller, Bernhard Kuster, Matthias Mann, Wilko Weichert, Stefan Fröhling, Roland Rad, Michael Hiltensperger, Angela M. Krackhardt
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-1 (2024)
Externí odkaz:
https://doaj.org/article/6cae0f5158ae4314ac4ec8b239aa4306
Autor:
Patrick Schöffski, Suzanne George, Michael C. Heinrich, John R. Zalcberg, Sebastian Bauer, Hans Gelderblom, César Serrano, Robin L. Jones, Steven Attia, Gina D’Amato, Ping Chi, Peter Reichardt, Claus Becker, Kelvin Shi, Julie Meade, Rodrigo Ruiz-Soto, Jean-Yves Blay, Margaret von Mehren
Publikováno v:
BMC Cancer, Vol 22, Iss 1, Pp 1-10 (2022)
Abstract Background Ripretinib is a novel switch-control kinase inhibitor that inhibits KIT and PDGFRA signaling. In the INVICTUS phase 3 trial, ripretinib increased median progression-free survival and prolonged overall survival vs. placebo in ≥ f
Externí odkaz:
https://doaj.org/article/9bb5658e944d433ba93df74a037e4505
Autor:
Sebastian Bauer, James Larkin, F. Stephen Hodi, Frank Stephen, Ellen H. W. Kapiteijn, Gary K. Schwartz, Emilano Calvo, Padmaja Yerramilli-Rao, Sophie Piperno-Neumann, Richard D. Carvajal
Publikováno v:
Frontiers in Oncology, Vol 12 (2023)
BackgroundUveal melanoma is a disease characterized by constitutive activation of the G alpha pathway and downstream signaling of protein kinase C (PKC) and the mitogen-activated protein kinase (MAPK) pathway. While limited clinical activity has been
Externí odkaz:
https://doaj.org/article/333ba02eee294c13b68620231919623d
Autor:
Maria A. Pantaleo, Michael C. Heinrich, Antoine Italiano, Claudia Valverde, Patrick Schöffski, Giovanni Grignani, Anna K. L. Reyners, Sebastian Bauer, Peter Reichardt, Daniel Stark, Ghimja Berhanu, Ulrike Brandt, Tommaso Stefanelli, Hans Gelderblom
Publikováno v:
BMC Cancer, Vol 22, Iss 1, Pp 1-8 (2022)
Abstract Background Acquired resistance to approved tyrosine kinase inhibitors limits their clinical use in patients with gastrointestinal stromal tumor (GIST). This study investigated the safety, tolerability and efficacy of alpelisib, a phosphatidy
Externí odkaz:
https://doaj.org/article/2f1e77cece464909a2d9a3ecf8c75f78
Autor:
Karsten Rink, Özgür Ozan Şen, Malte Schwanebeck, Tim Hartmann, Firdovsi Gasanzade, Johannes Nordbeck, Sebastian Bauer, Olaf Kolditz
Publikováno v:
Geothermal Energy, Vol 10, Iss 1, Pp 1-16 (2022)
Abstract The transition to renewable energy sources requires extensive changes to the energy system infrastructure, ranging from individual households to the national scale. During this transition, stakeholders must be able to make informed decisions
Externí odkaz:
https://doaj.org/article/4a39d2cc52904b4580babd1d2bd7fb22
Autor:
Benedikt M. Schaarschmidt, Alexis Slama, Stéphane Collaud, Özlem Okumus, Hannah Steinberg, Sebastian Bauer, Hans-Ulrich Schildhaus, Jens Theysohn, Clemens Aigner
Publikováno v:
European Radiology Experimental, Vol 6, Iss 1, Pp 1-11 (2022)
Abstract Background Transpulmonary embolisation (TPE) using degradable starch microspheres (DSM) is a potential approach to treat pulmonary metastases. However, there is a paucity of detailed information on perfusion dynamics. The aim of this study w
Externí odkaz:
https://doaj.org/article/b443f183da9d43eabe3b2bf04fd99037