Zobrazeno 1 - 10
of 38
pro vyhledávání: '"Sebastian Bäumer"'
Autor:
Nicole Bäumer, Annika Scheller, Lisa Wittmann, Andreas Faust, Mara Apel, Subbaiah Chary Nimmagadda, Christiane Geyer, Katharina Grunert, Neele Kellmann, Matthias Peipp, Sareetha Kailayangiri, Matias Ezequiel Gutierrez Suburu, Cristian A. Strassert, Mathias Schenk, Lilo Greune, Christian Rüter, Petra Dersch, Wolfgang Hartmann, Claudia Rossig, Dario Neri, Carsten Müller-Tidow, Christian Schwöppe, Christoph Schliemann, Cyrus Khandanpour, Georg Lenz, Wolfgang E. Berdel, Sebastian Bäumer
Publikováno v:
Journal of Hematology & Oncology, Vol 15, Iss 1, Pp 1-26 (2022)
Abstract Background Acute myeloid leukemia (AML) is a fatal clonal hematopoietic malignancy, which results from the accumulation of several genetic aberrations in myeloid progenitor cells, with a worldwide 5-year survival prognosis of about 30%. Ther
Externí odkaz:
https://doaj.org/article/522914dd6cf246468f2f5d959f5f9ca1
Autor:
Nicole Bäumer, Jan Rehkämper, Neele Appel, Lisa Terheyden, Wolfgang Hartmann, Eva Wardelmann, Frank Buchholz, Carsten Müller-Tidow, Wolfgang E Berdel, Sebastian Bäumer
Publikováno v:
PLoS ONE, Vol 13, Iss 7, p e0200163 (2018)
Precision cancer therapy requires on the one hand detailed knowledge about a tumor's driver oncogenes and on the other hand an effective targeted therapy that specifically inhibits these oncogenes. While the determination of genomic landscape of a tu
Externí odkaz:
https://doaj.org/article/5efa86aae4484dd99b3e519038989d02
Autor:
Nicole Bäumer, Sebastian Bäumer, Miriam Haak, Steffen Koschmieder, Kai Schönig, Wolfgang E Berdel, Carsten Müller-Tidow
Publikováno v:
PLoS ONE, Vol 10, Iss 6, p e0129147 (2015)
The quest for novel therapeutic targets in acute myeloid leukemia (AML) is still ongoing. One of such targets, cyclin A1, was shown to be overexpressed in AML including AML stem cells. However, the function of cyclin A1 in AML is largely unknown, and
Externí odkaz:
https://doaj.org/article/ae2828818cc444f6a4cc87c9356438c4
Publikováno v:
Archaea, Vol 1, Iss 1, Pp 1-7 (2002)
Analysis of genome sequence data from the methanogenic archaeon Methanosarcina mazei Gö1 revealed the existence of two open reading frames encoding proton-translocating pyrophosphatases (PPases). These open reading frames are linked by a 750-bp inte
Externí odkaz:
https://doaj.org/article/91cafdcabfd74d6db9d58b0b54b8cc35
Autor:
Nicole Bäumer, Annika Krause, Gabriele Köhler, Stephanie Lettermann, Georg Evers, Antje Hascher, Sebastian Bäumer, Wolfgang E Berdel, Carsten Müller-Tidow, Lara Tickenbrock
Publikováno v:
PLoS ONE, Vol 9, Iss 4, p e94993 (2014)
External signals that are mediated by specific receptors determine stem cell fate. The thrombin receptor PAR1 plays an important role in haemostasis, thrombosis and vascular biology, but also in tumor biology and angiogenesis. Its expression and func
Externí odkaz:
https://doaj.org/article/8bc3764f77df4944baac53412ce06122
Autor:
Nicole Bäumer, Sebastian Bäumer, Frank Berkenfeld, Martin Stehling, Gabriele Köhler, Wolfgang E Berdel, Carsten Müller-Tidow, Petra Tschanter
Publikováno v:
PLoS ONE, Vol 9, Iss 12, p e115578 (2014)
Functional differences between healthy progenitor and cancer initiating cells may provide unique opportunities for targeted therapy approaches. Hematopoietic stem cells are tightly controlled by a network of CDK inhibitors that govern proliferation a
Externí odkaz:
https://doaj.org/article/05686b6e0f03463584ea93fe677011f4
Autor:
Carsten Müller-Tidow, Wolfgang E. Berdel, Frank Buchholz, Eva Wardelmann, Sonja Schelhaas, Julia Fremerey, Lisa Terheyden, Neele Appel, Nicole Bäumer, Sebastian Bäumer
Supplementary Figure 1. Anti-EGFR antibody-protamine shuttles Alexa Fluor 488-labeled siRNA into EGFR-expressing cells.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::89e433e734946b68415b38ff24ea1af8
https://doi.org/10.1158/1078-0432.22451486
https://doi.org/10.1158/1078-0432.22451486
Autor:
Carsten Müller-Tidow, Wolfgang E. Berdel, Frank Buchholz, Eva Wardelmann, Sonja Schelhaas, Julia Fremerey, Lisa Terheyden, Neele Appel, Nicole Bäumer, Sebastian Bäumer
Supplementary Figure 6. Proliferation of HCT116 xenografted tumors upon mAB-siRNA treatment.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a686aaa33ed85fe98c216d458407454
https://doi.org/10.1158/1078-0432.22451468
https://doi.org/10.1158/1078-0432.22451468
Autor:
Carsten Müller-Tidow, Wolfgang E. Berdel, Frank Buchholz, Eva Wardelmann, Sonja Schelhaas, Julia Fremerey, Lisa Terheyden, Neele Appel, Nicole Bäumer, Sebastian Bäumer
Supplementary Figure 5. In vivo toxicity estimation by mouse body weight development.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a7fb730c13c14eaa9a84364ee0aa3fd8
https://doi.org/10.1158/1078-0432.22451474.v1
https://doi.org/10.1158/1078-0432.22451474.v1
Autor:
Carsten Müller-Tidow, Wolfgang E. Berdel, Frank Buchholz, Eva Wardelmann, Sonja Schelhaas, Julia Fremerey, Lisa Terheyden, Neele Appel, Nicole Bäumer, Sebastian Bäumer
Supplementary Figure 7 and Supplementary Figure 8. Figure S7: KRAS knockdown by mAB-KRASe siRNA in vivo Figure S8: Targeting cooperative oncogenes by mAB-esiRNA treatment.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2849678aabf340f4d43f52e57cad6427
https://doi.org/10.1158/1078-0432.22451462
https://doi.org/10.1158/1078-0432.22451462