Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Sebastian A, Wirz"'
Autor:
Natascha D. Diaco, Claudio Strickler, Stéphanie Giezendanner, Sebastian A. Wirz, Philip E. Tarr
Publikováno v:
EClinicalMedicine, Vol 6, Iss , Pp 21-25 (2018)
Background: Studies increasingly suggest that the efficacy of certain dual antiretroviral therapy (ART) combinations is equal to triple ART. Increasing concerns among HIV-positive patients and physicians in Switzerland include ART cost and long-term
Externí odkaz:
https://doaj.org/article/c4d1a2a361b54dbf98b0b299a23ba378
Autor:
Xiao-Ying Hua, Tamas Bartfai, Tie-Jun Sten Shi, Tomas Hökfelt, Jeff Kinney, Kristina Holmberg, Shelle Malkmus, Xiaoying Lu, Tony L. Yaksh, Sebastian A. Wirz, Sandra Ceccatelli
Publikováno v:
European Journal of Neuroscience. 23:627-636
Galanin is a 29-amino-acid peptide expressed in dorsal root ganglion (DRG) neurones and spinal dorsal horn neurones. It affects pain threshold and has developmental and trophic effects. Galanin acts at three G-protein-coupled receptors, galanin recep
Autor:
Alisdair M Barr, Jacinta Lucero, Pietro Paolo Sanna, Zane B. Andrews, Tamas L. Horvath, Tamas Bartfai, Covadonga Pañeda, Janell Pemberton, Bruno Conti, Pamela Maher, Sebastian A. Wirz, Svetlana Gaidarova, M. Margarita Behrens, Raphaelle Winsky-Sommerer, Maria C. Morale, Flint Beal, Shuei Sugama
Publikováno v:
Journal of Neurochemistry. 93:493-501
Oxidative stress is implicated in the death of dopaminergic neurons in sporadic forms of Parkinson's disease. Because oxidative stress can be modulated endogenously by uncoupling proteins (UCPs), we hypothesized that specific neuronal expression of U
Autor:
Stefano Sotgiu, Maura Pugliatti, Giulio Rosati, Bruno Conti, Sebastian A. Wirz, Orazio Giliberto, Bianca Marchetti, Maria C. Morale, Tamas Bartfai, Alasdair M. Barr, Maria Vittoria Sanna
Publikováno v:
Cytokine. 26:149-154
The G to A single nucleotide polymorphisms (SNPs), at position -376, -308 and -238 in the promoter of the tumor necrosis factor alpha (TNF) gene, have been independently correlated with numerous diseases. Alleles TNF(-376A) and TNF(-238A) are normall
Publikováno v:
Neuroscience. 128:451-458
Recent reports have revealed an involvement of microglial cells in dopaminergic neurodegeneration. In the present study, we tested the hypothesis that interleukin-18 (IL-18) plays a role in the microglial activation. The present study investigated mi
Autor:
Bruce T. Volpe, Gil C. Abalos, Dorian B. McGavern, Eliezer Masliah, Sebastian A. Wirz, Shuei Sugama, Donald H. Gilden, José R. Criado, Manuel Sanchez-Alavez, Bruno Conti, Erika Wiseman, R. Anthony Williamson, Michael B. A. Oldstone, Laura Solforosi, Lorraine A. DeGiorgio
Publikováno v:
Science. 303:1514-1516
Neuronal death is a prominent, but poorly understood, pathological hallmark of prion disease. Notably, in the absence of the cellular prion protein (PrP C ), the disease-associated isoform, PrP Sc , appears not to be intrinsically neurotoxic, suggest
Publikováno v:
Neuropeptides. 39(6)
Galanin is a 29- to 30-aa-long neuropeptide affecting feeding, cognitive, and sexual behavior. It exerts its effects through galanin receptors 1, 2 and 3, which are all seven transmembrane domain G-protein coupled receptors (GPCRs). The GPCRs have be
Publikováno v:
Neurochemical research. 31(2)
Neuroimmune interactions play a decisive role in neuronal cell survival and cell death during neuronal injury, oxidative and free radical stress. In neurons, NGF occupancy of p75 neurotrophin receptor (p75(NTR)) has been shown to promote neuronal apo
Autor:
Bruno, Conti, Shuei, Sugama, Jacinta, Lucero, Raphaelle, Winsky-Sommerer, Sebastian A, Wirz, Pamela, Maher, Zane, Andrews, Alasdair M, Barr, Maria C, Morale, Covadonga, Paneda, Janell, Pemberton, Svetlana, Gaidarova, M Margarita, Behrens, Flint, Beal, Pietro Paolo, Sanna, Tamas, Horvath, Tamas, Bartfai
Publikováno v:
Journal of neurochemistry. 93(2)
Oxidative stress is implicated in the death of dopaminergic neurons in sporadic forms of Parkinson's disease. Because oxidative stress can be modulated endogenously by uncoupling proteins (UCPs), we hypothesized that specific neuronal expression of U
Autor:
Sebastian A, Wirz, Maria C, Morale, Bianca, Marchetti, Alasdair M, Barr, Stefano, Sotgiu, Giulio, Rosati, Maura, Pugliatti, Maria Vittoria, Sanna, Orazio, Giliberto, Tamas, Bartfai, Bruno, Conti
Publikováno v:
Cytokine. 26(4)
The G to A single nucleotide polymorphisms (SNPs), at position -376, -308 and -238 in the promoter of the tumor necrosis factor alpha (TNF) gene, have been independently correlated with numerous diseases. Alleles TNF(-376A) and TNF(-238A) are normall