Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Sebastian Łukasiak"'
Autor:
Louise S. Matheson, Georg Petkau, Beatriz Sáenz-Narciso, Vanessa D’Angeli, Jessica McHugh, Rebecca Newman, Haydn Munford, James West, Krishnendu Chakraborty, Jennie Roberts, Sebastian Łukasiak, Manuel D. Díaz-Muñoz, Sarah E. Bell, Sarah Dimeloe, Martin Turner
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-24 (2022)
Abstract The ZFP36 family of RNA-binding proteins acts post-transcriptionally to repress translation and promote RNA decay. Studies of genes and pathways regulated by the ZFP36 family in CD4+ T cells have focussed largely on cytokines, but their impa
Externí odkaz:
https://doaj.org/article/502be5987af14790b105142b3363eb12
Autor:
Simon J. Cook, Sebastian Łukasiak, Alison Galloway, Anne E. Corcoran, Sara Ciullini Mannurita, Manuel D. Díaz-Muñoz, Martin R Turner, Elisa Monzón-Casanova, Kathryn Balmanno, Lewis S. Bell, Alexander Saveliev, Daniel J. Bolland, Helena Ahlfors, Daniel J. Hodson, Simon Andrews
Publikováno v:
Science. 352:453-459
Reducing the risk of rearrangement As lymphocytes develop, they rearrange their antigen receptor genes and proliferate extensively, potentially putting their genomes at risk. Galloway et al. found that two RNA-binding proteins, ZFP36L1 and ZFP36L2, e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::38228a10140f71fce09d1f9da2e96e5d
https://doi.org/10.1126/science.aad5978
https://doi.org/10.1126/science.aad5978
Autor:
Matthew A. Coelho, Etienne De Braekeleer, Mike Firth, Michal Bista, Sebastian Lukasiak, Maria Emanuela Cuomo, Benjamin J. M. Taylor
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-12 (2020)
Off-target editing remains a concern for therapeutic applications of CRISPR-Cas9. Here the authors present CRISPR GUARD, which uses very short non-cleaving gRNAs to prevent editing at off-target sites.
Externí odkaz:
https://doaj.org/article/5ca3e3c9d50c40859d3cc5b4b7665184