Zobrazeno 1 - 10
of 110
pro vyhledávání: '"Sebastian, Zundler"'
Autor:
Kim Wagner, Tanja M. Müller, Francesco Vitali, Sarah Fischer, Sophie Haberkamp, Rachel Rouse-Merkel, Raja Atreya, Markus F. Neurath, Sebastian Zundler
Publikováno v:
Therapeutic Advances in Gastroenterology, Vol 17 (2024)
Background: There is an increasing diversification in the treatment landscape for inflammatory bowel diseases (IBD) leading to therapeutic challenges that can only incompletely be covered by prospective randomized double-blind trials. Real-world obse
Externí odkaz:
https://doaj.org/article/0b42c0608bb84cbaa9ca90207dee411f
Autor:
Tanja Fererberger, Christa Buechler, Arne Kandulski, Tanja Elger, Johanna Loibl, Stephan Schmid, Stefanie Sommersberger, Stefan Gunawan, Sebastian Zundler, Muriel Huss, Dominik Bettenworth, Sally Kempa, Simon Weidlich, Bandik Föh, Xinyu Huang, Marcin Grzegorzek, Stefanie Derer-Petersen, Ulrich L. Günther, Jens U. Marquardt, Claudia Kunst, Karsten Gülow, Martina Müller, Christian Sina, Franziska Schmelter, Hauke C. Tews
Publikováno v:
Frontiers in Medicine, Vol 11 (2024)
IntoductionIdentification of specific metabolome and lipidome profile of patients with primary sclerosing cholangitis (PSC) is crucial for diagnosis, targeted personalized therapy, and more accurate risk stratification.MethodsNuclear magnetic resonan
Externí odkaz:
https://doaj.org/article/09253d97ee434a928fe26eb14955b0ba
Autor:
Maximilian Wiendl, Mark Dedden, Li-Juan Liu, Anna Schweda, Eva-Maria Paap, Karen A.-M. Ullrich, Leonie Hartmann, Luisa Wieser, Francesco Vitali, Imke Atreya, Tanja M. Müller, Claudia Günther, Raja Atreya, Markus F. Neurath, Sebastian Zundler
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-14 (2024)
Abstract Despite promising preclinical and earlier clinical data, a recent phase III trial on the anti-β7 integrin antibody etrolizumab in Crohn’s disease (CD) did not reach its primary endpoint. The mechanisms leading to this outcome are not well
Externí odkaz:
https://doaj.org/article/acac8322e2ba43b1966b2f33b0b17d77
Fiber rich food suppressed airway inflammation, GATA3 + Th2 cells, and FcεRIα+ eosinophils in asthma
Autor:
Alicia Schenzel, Adriana Geiger, Elvedina Nendel, Zuqin Yang, Susanne Krammer, Anna Leberle, Ann-Kathrin Brunst, Sonja Trump, Susanne Mittler, Manfred Rauh, Carol I. Geppert, Patrick Tausche, Katja Hohenberger, Ralf J. Rieker, Oliver Schieweck, Sebastian Zundler, Susetta Finotto
Publikováno v:
Frontiers in Nutrition, Vol 11 (2024)
BackgroundAllergic Asthma is a disease presenting various endotypes and no current therapies act curative but alleviate disease symptoms. Dietary interventions are gaining increasing importance in regulating immune responses. Furthermore, short chain
Externí odkaz:
https://doaj.org/article/39b0a87bb91247229f8164f0537f2605
Autor:
Francesco Vitali, Timo Rath, Entcho Klenske, Anna-Lena Vögele, Ingo Ganzleben, Sebastian Zundler, Deike Strobel, Carol Geppert, Arndt Hartmann, Markus F. Neurath, Raja Atreya
Publikováno v:
Therapeutic Advances in Gastroenterology, Vol 17 (2024)
Background: Effective management of patients with acute severe ulcerative colitis (ASUC) is a major challenge and there remains a paucity of available maintenance treatment options after efficacious cyclosporin induction therapy. Objectives: We inves
Externí odkaz:
https://doaj.org/article/6893d39668f04c80b05d2913832cad4b
Autor:
Katrin Sommer, Hilal Garibagaoglu, Eva-Maria Paap, Maximilian Wiendl, Tanja M. Müller, Imke Atreya, Gerhard Krönke, Markus F. Neurath, Sebastian Zundler
Publikováno v:
Cells, Vol 13, Iss 10, p 819 (2024)
Monocytes, as well as downstream macrophages and dendritic cells, are essential players in the immune system, fulfilling key roles in homeostasis as well as in inflammatory conditions. Conventionally, driven by studies on reporter models, mouse monoc
Externí odkaz:
https://doaj.org/article/2bf2d7289b8c4c54b8f81461aac155f8
Autor:
Timo Rath, Raja Atreya, Julia Bodenschatz, Wolfgang Uter, Carol I. Geppert, Francesco Vitali, Sebastian Zundler, Maximilian J. Waldner, Arndt Hartmann, Markus F. Neurath
Publikováno v:
Frontiers in Medicine, Vol 10 (2023)
BackgroundAchieving endoscopic remission is a key therapeutic goal in patients with ulcerative colitis (UC) that is associated with favorable long-term disease outcomes. Here, we prospectively compared the predictive value of endoscopic and/or histol
Externí odkaz:
https://doaj.org/article/4cd845a12a4f48249a51e409c3b313da
Autor:
Aylin Lindemann, Dominik Roth, Kristina Koop, Clemens Neufert, Sebastian Zundler, Raja Atreya, Markus F. Neurath, Moritz Leppkes
Publikováno v:
Frontiers in Medicine, Vol 10 (2023)
Background and aimsAcute severe steroid-refractory ulcerative colitis remains a medically challenging condition with frequent need of surgery. It can be treated with the calcineurin inhibitor cyclosporine A with the need for therapeutic drug monitori
Externí odkaz:
https://doaj.org/article/1cd45e5b0692471ea658653720605cdf
Autor:
Sebastian Zundler, Francesco Vitali, Soraya Kharboutli, Simon Völkl, Iris Polifka, Andreas Mackensen, Raja Atreya, Markus F. Neurath, Dimitrios Mougiakakos
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
Chimeric antigen receptor (CAR) T cell therapy has become a new mainstay in the treatment of several hematologic malignancies, but the spectrum of associated complications is still incompletely defined. Here, we report the case of a 70-year-old femal
Externí odkaz:
https://doaj.org/article/42dee58b8474466b9ab7b7acac47b13e
Autor:
Katrin Sommer, Karin Heidbreder, Lucas Kreiss, Mark Dedden, Eva‐Maria Paap, Maximilian Wiendl, Emily Becker, Raja Atreya, Tanja M. Müller, Imke Atreya, Maximilian Waldner, Sebastian Schürmann, Oliver Friedrich, Markus F. Neurath, Sebastian Zundler
Publikováno v:
Clinical and Translational Medicine, Vol 13, Iss 4, Pp n/a-n/a (2023)
Abstract Background Closing mucosal defects to reach mucosal healing is an important goal of therapy in inflammatory bowel disease (IBD). Among other cells, monocyte‐derived macrophages are centrally involved in such intestinal wound healing. We ha
Externí odkaz:
https://doaj.org/article/ac3db3afc3cb4b44b45838ef0d030115