Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Sebastian, Wrighton"'
Autor:
Arman Izadi, Yasaman Karami, Eleni Bratanis, Sebastian Wrighton, Hamed Khakzad, Maria Nyblom, Berit Olofsson, Lotta Happonen, Di Tang, Martin Sundwall, Magdalena Godzwon, Yashuan Chao, Alejandro Gomez Toledo, Tobias Schmidt, Mats Ohlin, Michael Nilges, Johan Malmström, Wael Bahnan, Oonagh Shannon, Lars Malmström, Pontus Nordenfelt
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-22 (2024)
Abstract Streptococcus pyogenes can cause invasive disease with high mortality despite adequate antibiotic treatments. To address this unmet need, we have previously generated an opsonic IgG1 monoclonal antibody, Ab25, targeting the bacterial M prote
Externí odkaz:
https://doaj.org/article/be6b5c313b7e4a23b226edf27ac9fea5
Autor:
Margit Anthofer, Markus Windisch, Rosa Haller, Sandra Ehmann, Sebastian Wrighton, Michael Miller, Lorenz Schernthanner, Iris Kufferath, Silvia Schauer, Barbara Jelušić, Sabine Kienesberger, Ellen L. Zechner, Gernot Posselt, Mar Vales-Gomez, Hugh T. Reyburn, Gregor Gorkiewicz
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
BackgroundHelicobacter pylori (H. pylori) uses various strategies that attenuate mucosal immunity to ensure its persistence in the stomach. We recently found evidence that H. pylori might modulate the natural killer group 2, member 2 (NKG2D) system.
Externí odkaz:
https://doaj.org/article/7eb6600bc12f45f996cdae771223c74f
Autor:
Wael Bahnan, Lotta Happonen, Hamed Khakzad, Vibha Kumra Ahnlide, Therese de Neergaard, Sebastian Wrighton, Oscar André, Eleni Bratanis, Di Tang, Thomas Hellmark, Lars Björck, Oonagh Shannon, Lars Malmström, Johan Malmström, Pontus Nordenfelt
Publikováno v:
EMBO Molecular Medicine, Vol 15, Iss 2, Pp 1-21 (2022)
Abstract Group A streptococci have evolved multiple strategies to evade human antibodies, making it challenging to create effective vaccines or antibody treatments. Here, we have generated antibodies derived from the memory B cells of an individual w
Externí odkaz:
https://doaj.org/article/2bcb7da2abe14c5fb5c5a0341f1349d2
Publikováno v:
Frontiers in Microbiology, Vol 14 (2023)
Group A streptococcus (GAS) is a highly adapted, human-specific pathogen that is known to manipulate the immune system through various mechanisms. GAS’ M protein constitutes a primary target of the immune system due to its spatial configuration and
Externí odkaz:
https://doaj.org/article/2da9ddbc4b9a4aadb088361a5272f306
Autor:
Lena Ohlsson, Christina Isaxon, Sebastian Wrighton, Wissal El Ouahidi, Lisa Fornell, Lena Uller, Saema Ansar, Ulrikke Voss
Publikováno v:
Physiological Reports, Vol 10, Iss 7, Pp n/a-n/a (2022)
Abstract Air pollution and exposure to fine airborne particles with aerodynamic diameter
Externí odkaz:
https://doaj.org/article/84ef1f6b1ce249928d62d187fa8ca747
Autor:
Vibha Kumra Ahnlide, Johannes Kumra Ahnlide, Sebastian Wrighton, Jason P Beech, Pontus Nordenfelt
Publikováno v:
eLife, Vol 11 (2022)
Antibody binding to cell surface proteins plays a crucial role in immunity, and the location of an epitope can altogether determine the immunological outcome of a host-target interaction. Techniques available today for epitope identification are cost
Externí odkaz:
https://doaj.org/article/6f9947c9651d4a3990b0f8b84d6011fc
Autor:
Wael Bahnan, Sebastian Wrighton, Martin Sundwall, Anna Bläckberg, Olivia Larsson, Urban Höglund, Hamed Khakzad, Magdalena Godzwon, Maria Walle, Elisabeth Elder, Anna Söderlund Strand, Lotta Happonen, Oscar André, Johannes Kumra Ahnlide, Thomas Hellmark, Vidar Wendel-Hansen, Robert PA. Wallin, Johan Malmstöm, Lars Malmström, Mats Ohlin, Magnus Rasmussen, Pontus Nordenfelt
Publikováno v:
Frontiers in Immunology, Vol 12 (2022)
Spike-specific antibodies are central to effective COVID19 immunity. Research efforts have focused on antibodies that neutralize the ACE2-Spike interaction but not on non-neutralizing antibodies. Antibody-dependent phagocytosis is an immune mechanism
Externí odkaz:
https://doaj.org/article/f92905abfadc4d269db7f2ae1d052963
Autor:
Arman Izadi, Arsema Hailu, Magdalena Godzwon, Sebastian Wrighton, Berit Olofsson, Tobias Schmidt, Anna Söderlund-Strand, Elizabeth Elder, Sofia Appelberg, Maria Valsjö, Olivia Larsson, Vidar Wendel-Hansen, Mats Ohlin, Wael Bahnan, Pontus Nordenfelt
Publikováno v:
Proceedings of the National Academy of Sciences. 120
Antibodies play a central role in the immune defense against SARS-CoV-2. Emerging evidence has shown that nonneutralizing antibodies are important for immune defense through Fc-mediated effector functions. Antibody subclass is known to affect downstr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::06e5b164ce1d91dfecb2117447cf9b5e
https://doi.org/10.1073/pnas.2217590120
https://doi.org/10.1073/pnas.2217590120
Publikováno v:
The Journal of Immunology. 206:214-224
Phagocytosis is measured as a functional outcome in many research fields, but accurate quantification can be challenging, with no robust method available for cross-laboratory reproducibility. In this study, we identified a simple, measurable paramete
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4322924619cce7752ae476469ed01ea5
https://doi.org/10.4049/jimmunol.2000032
https://doi.org/10.4049/jimmunol.2000032
Group A streptococcus (GAS) is a highly adapted, humanspecific pathogen that is known to manipulate the immune system through various mechanisms. GAS’ M protein constitutes a primary target of the immune system due to its spatial configuration and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::40883a9a1109fe0cb76e542a9902d089
https://doi.org/10.1101/2022.05.04.490590
https://doi.org/10.1101/2022.05.04.490590
