Zobrazeno 1 - 10
of 94
pro vyhledávání: '"Sebastian, Temme"'
Autor:
Timo Massold, Fady Ibrahim, Viola Niemann, Bodo Steckel, Katrin Becker, Jürgen Schrader, Johannes Stegbauer, Sebastian Temme, Maria Grandoch, Ulrich Flögel, Pascal Bouvain
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-15 (2023)
Abstract Vascular inflammation plays a key role in the development of aortic diseases. A potential novel target for treatment might be CD73, an ecto-5′-nucleotidase that generates anti-inflammatory adenosine in the extracellular space. Here, we inv
Externí odkaz:
https://doaj.org/article/275be7bceaad46c48123f7ca0ed2f78a
Autor:
Fabian Nienhaus, Moritz Walz, Maik Rothe, Annika Jahn, Susanne Pfeiler, Lucas Busch, Manuel Stern, Christian Heiss, Lilian Vornholz, Sandra Cames, Mareike Cramer, Vera Schrauwen-Hinderling, Norbert Gerdes, Sebastian Temme, Michael Roden, Ulrich Flögel, Malte Kelm, Florian Bönner
Publikováno v:
Journal of Cardiovascular Magnetic Resonance, Vol 25, Iss 1, Pp 1-13 (2023)
Abstract Background Macrophages play a pivotal role in vascular inflammation and predict cardiovascular complications. Fluorine-19 magnetic resonance imaging (19F MRI) with intravenously applied perfluorocarbon allows a background-free direct quantif
Externí odkaz:
https://doaj.org/article/dcde62c37ab64019abf83693a664081d
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 4, p 2312 (2024)
Acquisition of immunological memory is an important evolutionary strategy that evolved to protect the host from repetitive challenges from infectious agents. It was believed for a long time that memory formation exclusively occurs in the adaptive par
Externí odkaz:
https://doaj.org/article/086e6fe0015d49e7a3cee6f1ec701174
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
BackgroundInflammation and metabolism exhibit a complex interplay, where inflammation influences metabolic pathways, and in turn, metabolism shapes the quality of immune responses. Here, glucose turnover is of special interest, as proinflammatory imm
Externí odkaz:
https://doaj.org/article/cc0864acdbfa42428eaa7d7e9c29886a
Autor:
Ulrich Flögel, Sebastian Temme, Christoph Jacoby, Thomas Oerther, Petra Keul, Vera Flocke, Xiaowei Wang, Florian Bönner, Fabian Nienhaus, Karlheinz Peter, Jürgen Schrader, Maria Grandoch, Malte Kelm, Bodo Levkau
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-12 (2021)
The prediction of major cardiovascular events is still an unsolved problem. Here, the authors present a multi-color, multi-targeted non-invasive imaging technology that allows reliable in vivo identification of silent but prognostically highly releva
Externí odkaz:
https://doaj.org/article/63b7045c9fad435a95055854ca9ece41
Autor:
Stefan Hof, Carsten Marcus, Anne Kuebart, Jan Schulz, Richard Truse, Annika Raupach, Inge Bauer, Ulrich Flögel, Olaf Picker, Anna Herminghaus, Sebastian Temme
Publikováno v:
Frontiers in Medicine, Vol 9 (2022)
Impaired oxygen utilization is the underlying pathophysiological process in different shock states. Clinically most important are septic and hemorrhagic shock, which comprise more than 75% of all clinical cases of shock. Both forms lead to severe dys
Externí odkaz:
https://doaj.org/article/7298c05031864fe8878d6e977b4196fa
Autor:
Philipp Boehm-Sturm, Susanne Mueller, Nancy Freitag, Sophia Borowski, Marco Foddis, Stefan P. Koch, Sebastian Temme, Ulrich Flögel, Sandra M. Blois
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-10 (2021)
Abstract Placental hypoperfusion and hypoxia are key drivers in complications during fetal development such as fetal growth restriction and preeclampsia. In order to study the mechanisms of disease in mouse models, the development of quantitative bio
Externí odkaz:
https://doaj.org/article/2b1ff34c47de43fcb4f16e9a1d0714ed
Autor:
Tamara Straub, Julia Nave, Pascal Bouvain, Mohammad Akbarzadeh, Siva Sai Krishna Dasa, Julia Kistner, Zhaoping Ding, Aseel Marzoq, Stefanie Stepanow, Katrin Becker, Julia Hesse, Karl Köhrer, Ulrich Flögel, Mohammad R. Ahmadian, Brent A. French, Jürgen Schrader, Sebastian Temme
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-14 (2020)
Abstract After myocardial infarction (MI), epicardial cells reactivate their embryonic program, proliferate and migrate into the damaged tissue to differentiate into fibroblasts, endothelial cells and, if adequately stimulated, to cardiomyocytes. Tar
Externí odkaz:
https://doaj.org/article/926c75b0bc764b2880ee83245f14ba59
Autor:
Sebastian Temme, Mina Yakoub, Pascal Bouvain, Guang Yang, Jürgen Schrader, Johannes Stegbauer, Ulrich Flögel
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 8 (2021)
The pathophysiology of the initiation and progression of abdominal aortic aneurysms (AAAs) and aortic dissections (AADs) is still unclear. However, there is strong evidence that monocytes and macrophages are of crucial importance in these processes.
Externí odkaz:
https://doaj.org/article/a2d5f614f9f14f88af43099fdfd32f90
Autor:
Dung N. Nguyen, Bokai Xu, Robyn L. Stanfield, Jennifer K. Bailey, Satoru Horiya, J. Sebastian Temme, Deborah R. Leon, Celia C. LaBranche, David C. Montefiori, Catherine E. Costello, Ian A. Wilson, Isaac J. Krauss
Publikováno v:
ACS Central Science, Vol 5, Iss 2, Pp 237-249 (2019)
Externí odkaz:
https://doaj.org/article/9f4707366b53402dbecdc17a9b42eefa