Zobrazeno 1 - 10
of 268
pro vyhledávání: '"Sebastian, Suerbaum"'
Publikováno v:
BMC Biology, Vol 22, Iss 1, Pp 1-22 (2024)
Abstract Background Bacterial epigenetics is a rapidly expanding research field. DNA methylation by diverse bacterial methyltransferases (MTases) contributes to genomic integrity and replication, and many recent studies extended MTase function also t
Externí odkaz:
https://doaj.org/article/9f196c903e5a437b9505e565c111ec38
Publikováno v:
Frontiers in Molecular Biosciences, Vol 11 (2024)
External Quality Assessment schemes (EQAS) are mandatory to ensure quality standards in diagnostic methods and achieve laboratory accreditation. As host institution for two German culture-based bacteriology EQAS (RV-A and RV-B), we investigated the o
Externí odkaz:
https://doaj.org/article/ce3af6dd064041ec8533edd077e91e1b
Publikováno v:
International Journal of Medical Microbiology, Vol 314, Iss , Pp 151617- (2024)
Externí odkaz:
https://doaj.org/article/6d72e31d21fa40ca86809a366e555016
Methylome evolution suggests lineage-dependent selection in the gastric pathogen Helicobacter pylori
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-13 (2023)
Abstract The bacterial pathogen Helicobacter pylori, the leading cause of gastric cancer, is genetically highly diverse and harbours a large and variable portfolio of restriction-modification systems. Our understanding of the evolution and function o
Externí odkaz:
https://doaj.org/article/2e86f9df8e554556bf5239307affc551
Autor:
Karl Dichtl, Andreas Osterman, Johannes Forster, Lena Jakob, Sebastian Suerbaum, Michael J. Flaig, Sören Schubert, Johannes Wagener
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-7 (2023)
Abstract With an incidence of more than > 1,000,000/day, sexually transmitted diseases remain a major challenge for health care systems worldwide. To reduce disease burden, complications, and spread, rapid diagnosis permitting early therapy is pivota
Externí odkaz:
https://doaj.org/article/7039c6dc5c284fbf840d385c20a371ed
Autor:
Harry A. Thorpe, Elise Tourrette, Koji Yahara, Filipa F. Vale, Siqi Liu, Mónica Oleastro, Teresa Alarcon, Tsachi-Tsadok Perets, Saeid Latifi-Navid, Yoshio Yamaoka, Beatriz Martinez-Gonzalez, Ioannis Karayiannis, Timokratis Karamitros, Dionyssios N. Sgouras, Wael Elamin, Ben Pascoe, Samuel K. Sheppard, Jukka Ronkainen, Pertti Aro, Lars Engstrand, Lars Agreus, Sebastian Suerbaum, Kaisa Thorell, Daniel Falush
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-11 (2022)
Helicobacter pylori is a major human pathogen whose population structure is similar to that of its host. Here, the authors show that H. pylori has repeatedly spread out of Africa recently, replacing deleterious variants that accumulated during the or
Externí odkaz:
https://doaj.org/article/54287d44e6a344f886d3d297e6a9f657
Autor:
Sebastian Suerbaum, Nina Coombs, Lubna Patel, Dimitri Pscheniza, Katharina Rox, Christine Falk, Achim D. Gruber, Olivia Kershaw, Patrick Chhatwal, Mark Brönstrup, Ursula Bilitewski, Christine Josenhans
Publikováno v:
mBio, Vol 13, Iss 5 (2022)
Externí odkaz:
https://doaj.org/article/e76f3508d5c14d18a67d2816e6e1fe80
Publikováno v:
mBio, Vol 13, Iss 4 (2022)
ABSTRACT Helicobacter pylori is a Gram-negative bacterial carcinogenic pathogen that infects the stomachs of half of the human population. It is a natural mutator due to a deficient DNA mismatch repair pathway and is naturally competent for transform
Externí odkaz:
https://doaj.org/article/c33911a13f4b41d782f37a716eebbc58
Autor:
Harry A. Thorpe, Elise Tourrette, Koji Yahara, Filipa F. Vale, Siqi Liu, Mónica Oleastro, Teresa Alarcon, Tsachi-Tsadok Perets, Saeid Latifi-Navid, Yoshio Yamaoka, Beatriz Martinez-Gonzalez, Ioannis Karayiannis, Timokratis Karamitros, Dionyssios N. Sgouras, Wael Elamin, Ben Pascoe, Samuel K. Sheppard, Jukka Ronkainen, Pertti Aro, Lars Engstrand, Lars Agreus, Sebastian Suerbaum, Kaisa Thorell, Daniel Falush
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-1 (2023)
Externí odkaz:
https://doaj.org/article/25c6cc6f8bd84742943ca0a3a9ed13a5
Autor:
Sebastian Suerbaum, Nina Coombs, Lubna Patel, Dimitri Pscheniza, Katharina Rox, Christine Falk, Achim D. Gruber, Olivia Kershaw, Patrick Chhatwal, Mark Brönstrup, Ursula Bilitewski, Christine Josenhans
Publikováno v:
mBio, Vol 13, Iss 2 (2022)
ABSTRACT New treatment options against the widespread cancerogenic gastric pathogen Helicobacter pylori are urgently needed. We describe a novel screening procedure for inhibitors of H. pylori flagellar biosynthesis. The assay is based on a flaA flag
Externí odkaz:
https://doaj.org/article/23a756c0b8254db1bc9461c34a8acd08