Zobrazeno 1 - 10
of 57
pro vyhledávání: '"Sebastian, Königsberger"'
Autor:
Sebastian Königsberger, Nicole Sänger, Fadi Bakjaji, Jasper Verguts, Cara Färber, Andreas Schallmoser, Jean-Pierre Allam, Elke Schmidt, Julia John, Hannelore Breitenbach-Koller
Publikováno v:
Transl Androl Urol
Background: Highly viscous semen reduces sperm motility significantly and can contribute to infertility. When processing semen samples, few techniques exist to induce liquefaction in case of seminal hyperviscosity such as different washing steps and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::11e8eb3ca86a890795ed7593b1370fda
https://pubmed.ncbi.nlm.nih.gov/33532332
https://pubmed.ncbi.nlm.nih.gov/33532332
Autor:
Sebastian Königsberger, Doris Peckl-Schmid, Nadja Zaborsky, Irene Patzak, Friedemann Kiefer, Gernot Achatz
Publikováno v:
PLoS ONE, Vol 5, Iss 9, p e12468 (2010)
Hematopoietic progenitor kinase 1 (HPK1) is a Ste20-related serine/threonine kinase activated by a range of environmental stimuli including genotoxic stress, growth factors, inflammatory cytokines and antigen receptor triggering. Being inducibly recr
Externí odkaz:
https://doaj.org/article/b50c7e23cadc4b17b2bb1867c68e8751
Autor:
Hermann Einsele, Lydia Scharf, Johannes B. Huppa, Hannes Stockinger, Julian Rydzek, Sebastian Königsberger, Michael Hudecek, Iago Doel Perez, Venugopal Gudipati
Rational design of chimeric antigen receptors (CARs) with optimized anti-cancer performance mandates detailed knowledge of how CARs engage tumor antigens and how antigen-engagement triggers activation. We analyzed CAR-mediated antigen recognition via
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::446144110f90e8e5f7d272d9dcaf7ade
https://doi.org/10.1101/720417
https://doi.org/10.1101/720417
Autor:
Venugopal, Gudipati, Julian, Rydzek, Iago, Doel-Perez, Vasco Dos Reis, Gonçalves, Lydia, Scharf, Sebastian, Königsberger, Elisabeth, Lobner, Renate, Kunert, Hermann, Einsele, Hannes, Stockinger, Michael, Hudecek, Johannes B, Huppa
Publikováno v:
Nature immunology. 21(8)
Rational design of chimeric antigen receptors (CARs) with optimized anticancer performance mandates detailed knowledge of how CARs engage tumor antigens and how antigen engagement triggers activation. We analyzed CAR-mediated antigen recognition via
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::141087fba08d797158b1de20fd4ad780
https://pubmed.ncbi.nlm.nih.gov/32632290
https://pubmed.ncbi.nlm.nih.gov/32632290
Autor:
Andreas Schallmoser, Monika Raab, Elke Schmidt, Sebastian Königsberger, Hannelore Breitenbach-Koller, Thomas Karn, Nicole Sänger
Publikováno v:
American Journal of Reproductive Immunology. 82
Background Recent studies revealed that maternal and embryonic contributions impact on HLA-G protein expression and might contribute to pregnancy success or failure. The main objective of this study was to examine the paternal levels of the immunoreg
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b1fa182866775b642801eef9520d9f27
https://doi.org/10.1111/aji.13152
https://doi.org/10.1111/aji.13152
Publikováno v:
Molecular and Cellular Biology. 37
The nonreceptor tyrosine kinase Syk, a central regulator of immune cell differentiation and activation, is a promising drug target for treatment of leukemia and allergic and inflammatory diseases. The clinical failure of Syk inhibitors underscores th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::648a29ab1fda684d7b5e780293ae922d
https://doi.org/10.1128/mcb.00216-17
https://doi.org/10.1128/mcb.00216-17
Publikováno v:
The EMBO Journal. 34:838-840
The TNF receptor family member BAFFR is essential for providing mature B cells with pro‐survival signals and has recently been claimed to transduce these, though not exclusively, via a Syk‐dependent signaling hub that feeds into ERK/AKT activatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6062542c3f2331b1d91c0206252c4479
https://doi.org/10.15252/embj.201591120
https://doi.org/10.15252/embj.201591120
Autor:
Ruben Böhmer, Ina Thielmann, Bernhard Nieswandt, Jan Prodöhl, Friedemann Kiefer, Vanessa Weis, Theresa Schumacher, Judith M.M. van Eeuwijk, Martin Andreas, Sebastian Königsberger, Martin Stehling, David Stegner
Publikováno v:
The EMBO Journal. 31:3363-3374
The spleen tyrosine kinase family members Syk and Zap-70 are pivotal signal transducers downstream of antigen receptors and exhibit overlapping expression patterns at early lymphocytic developmental stages. To assess their differential kinase fitness
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e79e1eea556fb5b4d8bce4908bdb7347
https://doi.org/10.1038/emboj.2012.169
https://doi.org/10.1038/emboj.2012.169
Publikováno v:
European Journal of Immunology. 40:3220-3225
The hematopoietic progenitor kinase 1 (HPK1) signals into MAPK and NFκB pathways downstream of immunoreceptors, but enigmatically is a negative regulator of leukocytes. Here, we report a novel role for HPK1 in regulating the activation of the adhesi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a6707fe7ce952f48189975a084460ab4
https://doi.org/10.1002/eji.201040313
https://doi.org/10.1002/eji.201040313