Výsledky vyhledávání - "Sebastian, Duncan"

Akademický článek

Development of a universal, oriented antibody immobilization method to functionalize vascular prostheses for enhanced endothelialization for potential clinical application

Autor: Qiuwang Zhang, Sebastian Duncan, Daniel A. Szulc, Charles de Mestral, Michael JB Kutryk

Publikováno v: Journal of Biological Engineering, Vol 17, Iss 1, Pp 1-15 (2023)

Abstract Background Thrombosis is a common cause of vascular prosthesis failure. Antibody coating of prostheses to capture circulating endothelial progenitor cells to aid endothelialization on the device surface appears a promising solution to preven

Externí odkaz: https://doaj.org/article/92522e3d914c41f3b53cc49a8c10f50a

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Antibody functionalized intravascular devices combined with genetically engineered endothelial colony-forming cells for targeted drug delivery: A proof-of-concept study

Autor: Qiuwang, Zhang, Sebastian, Duncan, Daniel A, Szulc, Michael J B, Kutryk

Publikováno v: European Journal of Pharmaceutics and Biopharmaceutics. 181:218-226

This study was designed to test the ability of ex vivo antibody-coated intravascular devices to capture genetically engineered pig endothelial colony-forming cells (ECFCs) as proof of concept for their potential for in vivo targeted drug delivery. Hu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::33d70e4b7f023e45e0bb7368bc140a0c
https://doi.org/10.1016/j.ejpb.2022.11.015

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The predicted collagen-binding domains of Drosophila SPARC are essential for survival and for collagen IV distribution and assembly into basement membranes

Autor: Sebastian Duncan, Olga Sirbu, Samuel Delage, Maurice J. Ringuette, Alexa Chioran, Theodore J. Brown

Publikováno v: Developmental biology. 461(2)

The assembly of basement membranes (BMs) into tissue-specific morphoregulatory structures requires non-core BM components. Work in Drosophila indicates a principal role of collagen-binding matricellular glycoprotein SPARC (Secreted Protein, Acidic, R

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4162fd551517ee1107247fcdacdd034a
https://pubmed.ncbi.nlm.nih.gov/32087195

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Collagen-binding byDrosophilaSPARC is essential for survival and for collagen IV distribution and assembly into basement membranes

Autor: Olga Sirbu, Sebastian Duncan, Alexa Chioran, Theodore J. Brown, S. Delage, Maurice J. Ringuette

The assembly of basement membranes (BMs) into tissue-specific morphoregulatory structures requires non-core BM components. Work inDrosophilaindicates a principal role of collagen-binding matricellular glycoprotein SPARC (Secreted Protein, Acidic, Ric

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::864fb4bab6e00d46d6918ca34ecdc2eb
https://doi.org/10.1101/714378

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Collagen IV trafficking: The inside-out and beyond story

Autor: Alexa Chioran, Sebastian Duncan, Maurice J. Ringuette, Andrew Catalano, Theodore J. Brown

Publikováno v: Developmental biology. 431(2)

Collagen IV networks endow basement membranes (BMs) with remarkable tensile strength and function as morphoregulatory substrata for diverse tissue-specific developmental events. A complex repertoire of intracellular and extracellular molecular intera

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f9ac928cf9fd160fe0310280174c1209
https://pubmed.ncbi.nlm.nih.gov/28982537

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