Zobrazeno 1 - 10
of 113
pro vyhledávání: '"Sebastian, Clauss"'
Autor:
Julia Bauer, Julia Vlcek, Valerie Pauly, Nora Hesse, Ruibing Xia, Li Mo, Aparna Sharma Chivukula, Hannes Villgrater, Marie Dressler, Bianca Hildebrand, Eckhard Wolf, Konstantinos D. Rizas, Axel Bauer, Stefan Kääb, Philipp Tomsits, Dominik Schüttler, Sebastian Clauss
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 13, Iss 9 (2024)
Background Periodic repolarization dynamics (PRD) is an electrocardiographic biomarker that captures repolarization instability in the low frequency spectrum and is believed to estimate the sympathetic effect on the ventricular myocardium. High PRD i
Externí odkaz:
https://doaj.org/article/ec48d6e8e9fe460fbf10c6b6402d7e9c
Autor:
Fitzwilliam Seibertz, Markus Rapedius, Funsho E. Fakuade, Philipp Tomsits, Aiste Liutkute, Lukas Cyganek, Nadine Becker, Rupamanjari Majumder, Sebastian Clauß, Niels Fertig, Niels Voigt
Publikováno v:
Communications Biology, Vol 5, Iss 1, Pp 1-10 (2022)
An altered automated patch-clamp (APC) approach enables high-throughput recordings from native pig cardiomyocytes and human iPSC-derived cardiomyocytes.
Externí odkaz:
https://doaj.org/article/5c7c79c8eaee40c1b5ac7523e292a2bf
Autor:
Maria Shoykhet, Orsela Dervishi, Philipp Menauer, Matthias Hiermaier, Sina Moztarzadeh, Colin Osterloh, Ralf J. Ludwig, Tatjana Williams, Brenda Gerull, Stefan Kääb, Sebastian Clauss, Dominik Schüttler, Jens Waschke, Sunil Yeruva
Publikováno v:
JCI Insight, Vol 8, Iss 6 (2023)
Arrhythmogenic cardiomyopathy (AC) is a familial heart disease partly caused by impaired desmosome turnover. Thus, stabilization of desmosome integrity may provide new treatment options. Desmosomes, apart from cellular cohesion, provide the structura
Externí odkaz:
https://doaj.org/article/2beededbb67b40438a622d5e5d48e306
Autor:
Ruibing Xia, Philipp Tomsits, Simone Loy, Zhihao Zhang, Valerie Pauly, Dominik Schüttler, Sebastian Clauss
Publikováno v:
Frontiers in Physiology, Vol 13 (2022)
Cardiac electrophysiology is a complex system established by a plethora of inward and outward ion currents in cardiomyocytes generating and conducting electrical signals in the heart. However, not only cardiomyocytes but also other cell types can mod
Externí odkaz:
https://doaj.org/article/870bf62b217f471e9bf8c38cfeb88cfa
Autor:
Valerie Pauly, Julia Vlcek, Zhihao Zhang, Nora Hesse, Ruibing Xia, Julia Bauer, Simone Loy, Sarah Schneider, Simone Renner, Eckhard Wolf, Stefan Kääb, Dominik Schüttler, Philipp Tomsits, Sebastian Clauss
Publikováno v:
Cells, Vol 12, Iss 7, p 973 (2023)
Atrial fibrillation (AF) is the most prevalent arrhythmia, often caused by myocardial ischemia/infarction (MI). Men have a 1.5× higher prevalence of AF, whereas women show a higher risk for new onset AF after MI. However, the underlying mechanisms o
Externí odkaz:
https://doaj.org/article/aa21fbdebe6344298b3f2eaa5627eecf
Autor:
Philipp Tomsits, Lina Volz, Ruibing Xia, Aparna Chivukula, Dominik Schüttler, Sebastian Clauß
Publikováno v:
Lab Animal. 52:85-92
Arrhythmias are critical contributors to cardiovascular morbidity and mortality. Therapies are mainly symptomatic and often insufficient, emphasizing the need for basic research to unveil the mechanisms underlying arrhythmias and to enable better and
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 8 (2021)
Chronic thrombo-embolic pulmonary hypertension (CTEPH) develops in a subset of patients after acute pulmonary embolism. In CTEPH, pulmonary vascular resistance, which is initially elevated due to the obstructions in the larger pulmonary arteries, is
Externí odkaz:
https://doaj.org/article/2186c9541ded466fbf1dbb1031479c82
Autor:
Aenne S. von Falkenhausen, Katharina Feil, Moritz F. Sinner, Sonja Schönecker, Johanna Müller, Johannes Wischmann, Elodie Eiffener, Sebastian Clauss, Sven Poli, Khouloud Poli, Christine S. Zuern, Ulf Ziemann, Jörg Berrouschot, Alkisti Kitsiou, Wolf‐Rüdiger Schäbitz, Marianne Dieterich, Steffen Massberg, Stefan Kääb, Lars Kellert
Publikováno v:
Annals of Neurology. 93:479-488
Objective: Approximately 20% of strokes are embolic strokes of undetermined source (ESUS). Undetected atrial fibrillation (AF) remains an important cause. Yet, oral anticoagulation in unselected ESUS patients failed in secondary stroke prevention. Gu
Autor:
Sebastian Clauss, Dominik Schüttler, Christina Bleyer, Julia Vlcek, Mehdi Shakarami, Philipp Tomsits, Sarah Schneider, Florian Maderspacher, Kavi Chataut, Anna Trebo, Christine Wang, Jan Kleeberger, Ruibing Xia, Elisabeth Baloch, Bianca Hildebrand, Steffen Massberg, Reza Wakili, Stefan Kääb
Publikováno v:
PLoS ONE, Vol 15, Iss 5, p e0232374 (2020)
Atrial fibrillation (AF) is a major healthcare challenge contributing to high morbidity and mortality. Treatment options are still limited, mainly due to insufficient understanding of the underlying pathophysiology. Further research and the developme
Externí odkaz:
https://doaj.org/article/f2090773d7044e99aecaa468c7137ee2
Publikováno v:
Journal of Composites Science, Vol 5, Iss 6, p 150 (2021)
In automotive manufacturing, laminated veneer sheets are formed to have 3D geometries for the production of trim parts with wood surfaces. Nowadays, investigation of the formability requires extensive tests with prototype tools, due to the brittle, a
Externí odkaz:
https://doaj.org/article/91c3cddc80344cb7b23c13860f7161f0