Zobrazeno 1 - 10
of 59
pro vyhledávání: '"Sebastian, Baumgarten"'
Autor:
Jessica Bryant, Sebastian Baumgarten
Publikováno v:
Open Research Europe, Vol 2 (2022)
Background: The maintenance, regulation, and dynamics of heterochromatin in the human malaria parasite, Plasmodium falciparum, has drawn increasing attention due to its regulatory role in mutually exclusive virulence gene expression and the silencing
Externí odkaz:
https://doaj.org/article/77379df236524cb4918cd99dcbcaf84c
Autor:
Elie Hammam, Ameya Sinha, Sebastian Baumgarten, Flore Nardella, Jiaqi Liang, Samia Miled, Frédéric Bonhomme, Diane Erdmann, Benoit Arcangioli, Paola B. Arimondo, Peter Dedon, Peter Preiser, Artur Scherf
Publikováno v:
mBio, Vol 12, Iss 6 (2021)
ABSTRACT Malaria parasites need to cope with changing environmental conditions that require strong countermeasures to ensure pathogen survival in the human and mosquito hosts. The molecular mechanisms that protect Plasmodium falciparum homeostasis du
Externí odkaz:
https://doaj.org/article/4ab8bce2ce6542b2a0f1956d001448d1
Autor:
Ameya Sinha, Sebastian Baumgarten, Amy Distiller, Emma McHugh, Patty Chen, Meetali Singh, Jessica M. Bryant, Jiaqi Liang, Germano Cecere, Peter C. Dedon, Peter R. Preiser, Stuart A. Ralph, Artur Scherf
Publikováno v:
mBio, Vol 12, Iss 2 (2021)
Infection with the unicellular eukaryotic pathogen Plasmodium falciparum
Externí odkaz:
https://doaj.org/article/6a4838d372414cd098219b2fa7597358
Autor:
Jessica M Bryant, Sebastian Baumgarten, Florent Dingli, Damarys Loew, Ameya Sinha, Aurélie Claës, Peter R Preiser, Peter C Dedon, Artur Scherf
Publikováno v:
Molecular Systems Biology, Vol 16, Iss 8, Pp n/a-n/a (2020)
Abstract Mutually exclusive expression of the var multigene family is key to immune evasion and pathogenesis in Plasmodium falciparum, but few factors have been shown to play a direct role. We adapted a CRISPR‐based proteomics approach to identify
Externí odkaz:
https://doaj.org/article/1b263eb127434a03a0f52b64bd894d4b
A Specific PfEMP1 Is Expressed in P. falciparum Sporozoites and Plays a Role in Hepatocyte Infection
Autor:
Gigliola Zanghì, Shruthi S. Vembar, Sebastian Baumgarten, Shuai Ding, Julien Guizetti, Jessica M. Bryant, Denise Mattei, Anja T.R. Jensen, Laurent Rénia, Yun Shan Goh, Robert Sauerwein, Cornelus C. Hermsen, Jean-François Franetich, Mallaury Bordessoulles, Olivier Silvie, Valérie Soulard, Olivier Scatton, Patty Chen, Salah Mecheri, Dominique Mazier, Artur Scherf
Publikováno v:
Cell Reports, Vol 22, Iss 11, Pp 2951-2963 (2018)
Summary: Heterochromatin plays a central role in the process of immune evasion, pathogenesis, and transmission of the malaria parasite Plasmodium falciparum during blood stage infection. Here, we use ChIP sequencing to demonstrate that sporozoites fr
Externí odkaz:
https://doaj.org/article/939c4b5bec404e3d98afcc5d3b2f4e81
Autor:
Lauren K. Yum, Sebastian Baumgarten, Till Röthig, Cornelia Roder, Anna Roik, Craig Michell, Christian R. Voolstra
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-11 (2017)
Abstract Despite the importance of deep-sea corals, our current understanding of their ecology and evolution is limited due to difficulties in sampling and studying deep-sea environments. Moreover, a recent re-evaluation of habitat limitations has be
Externí odkaz:
https://doaj.org/article/bb72773d107e4b2d84b5bc89cac45898
Autor:
Marta Tibúrcio, Annie S. P. Yang, Kazuhide Yahata, Pablo Suárez-Cortés, Hugo Belda, Sebastian Baumgarten, Marga van de Vegte-Bolmer, Geert-Jan van Gemert, Youri van Waardenburg, Elena A. Levashina, Robert W. Sauerwein, Moritz Treeck
Publikováno v:
mBio, Vol 10, Iss 5 (2019)
ABSTRACT Plasmodium falciparum has a complex life cycle that involves interaction with multiple tissues inside the human and mosquito hosts. Identification of essential genes at all different stages of the P. falciparum life cycle is urgently require
Externí odkaz:
https://doaj.org/article/3cbe7693f30c4d82ba23a68fa6ecdc4b
Autor:
Catarina Rosa, Parul Singh, Patty Chen, Ameya Sinha, Peter Rainer Preiser, Peter C. Dedon, Sebastian Baumgarten, Artur Scherf, Jessica Michelle Bryant
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::811b2a7e5779043fad2b8cd3b8853e12
https://doi.org/10.15252/rc.2023409879
https://doi.org/10.15252/rc.2023409879
Autor:
Fabien Sindikubwabo, Shuai Ding, Tahir Hussain, Philippe Ortet, Mohamed Barakat, Sebastian Baumgarten, Dominique Cannella, Andrés Palencia, Alexandre Bougdour, Lucid Belmudes, Yohann Couté, Isabelle Tardieux, Cyrille Y Botté, Artur Scherf, Mohamed-ali Hakimi
Publikováno v:
eLife, Vol 6 (2017)
An unusual genome architecture characterizes the two related human parasitic pathogens Plasmodium falciparum and Toxoplasma gondii. A major fraction of the bulk parasite genome is packaged as transcriptionally permissive euchromatin with few loci emb
Externí odkaz:
https://doaj.org/article/29a46b45901548e0861e8f922ce14127