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pro vyhledávání: '"Sebastiaan T A, Koenders"'
Autor:
Sebastiaan T. A. Koenders, Lukas S. Wijaya, Martje N. Erkelens, Alexander T. Bakker, Vera E. van der Noord, Eva J. van Rooden, Lindsey Burggraaff, Pasquale C. Putter, Else Botter, Kim Wals, Hans van den Elst, Hans den Dulk, Bogdan I. Florea, Bob van de Water, Gerard J. P. van Westen, Reina E. Mebius, Herman S. Overkleeft, Sylvia E. Le Dévédec, Mario van der Stelt
Publikováno v:
ACS Central Science, Vol 5, Iss 12, Pp 1965-1974 (2019)
Externí odkaz:
https://doaj.org/article/989e2de45d314bdeb9af0694f21eb017
Autor:
Hans den Dulk, Reina E Mebius, Eva J. van Rooden, Hans van den Elst, Pasquale C Putter, Bob van de Water, Else Botter, Gerard J. P. van Westen, Alexander T Bakker, Vera E. van der Noord, Bogdan I. Florea, Mario van der Stelt, Kim Wals, Sylvia E. Le Dévédec, Sebastiaan T A Koenders, Herman S. Overkleeft, Lukas S Wijaya, Martje N. Erkelens, Lindsey Burggraaff
Publikováno v:
ACS Central Science, Vol 5, Iss 12, Pp 1965-1974 (2019)
ACS Central Science, 5(12), 1965-1974
ACS Central Science, 5(12), 1965-1974. American Chemical Society
ACS Central Science
Koenders, S T A, Wijaya, L S, Erkelens, M N, Bakker, A T, van der Noord, V E, van Rooden, E J, Burggraaff, L, Putter, P C, Botter, E, Wals, K, van den Elst, H, den Dulk, H, Florea, B I, van de Water, B, van Westen, G J P, Mebius, R E, Overkleeft, H S, Le Dévédec, S E & van der Stelt, M 2019, ' Development of a Retinal-Based Probe for the Profiling of Retinaldehyde Dehydrogenases in Cancer Cells ', ACS Central Science, vol. 5, no. 12, pp. 1965-1974 . https://doi.org/10.1021/acscentsci.9b01022
ACS Central Science, 5(12), 1965-1974
ACS Central Science, 5(12), 1965-1974. American Chemical Society
ACS Central Science
Koenders, S T A, Wijaya, L S, Erkelens, M N, Bakker, A T, van der Noord, V E, van Rooden, E J, Burggraaff, L, Putter, P C, Botter, E, Wals, K, van den Elst, H, den Dulk, H, Florea, B I, van de Water, B, van Westen, G J P, Mebius, R E, Overkleeft, H S, Le Dévédec, S E & van der Stelt, M 2019, ' Development of a Retinal-Based Probe for the Profiling of Retinaldehyde Dehydrogenases in Cancer Cells ', ACS Central Science, vol. 5, no. 12, pp. 1965-1974 . https://doi.org/10.1021/acscentsci.9b01022
Retinaldehyde dehydrogenases belong to a superfamily of enzymes that regulate cell differentiation and are responsible for detoxification of anticancer drugs. Chemical tools and methods are of great utility to visualize and quantify aldehyde dehydrog
Autor:
Sebastiaan T A Koenders, Bogdan I. Florea, Mario van der Stelt, Hans van den Elst, Herman S. Overkleeft, Eva J. van Rooden
Publikováno v:
CHEMBIOCHEM
CHEMBIOCHEM, 21, 1911-1917. WILEY-V C H VERLAG GMBH
CHEMBIOCHEM, 21, 1911-1917. WILEY-V C H VERLAG GMBH
Aldehyde dehydrogenases (ALDHs) convert aldehydes into carboxylic acids and are often upregulated in cancer. They have been linked to therapy resistance and are therefore potential therapeutic targets. However, only a few selective and potent inhibit
Publikováno v:
Current topics in microbiology and immunology. 420
Lipids perform a wide range of functions inside the cell, ranging from structural building block of membranes and energy storage to cell signaling. The mode of action of many signaling lipids has remained elusive due to their low abundance, high lipo