Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Sebastiaan Johannes Trietsch"'
Autor:
Benjamin Smith, Remko van Vught, Taylor Gray, Paul Vulto, Nienke R. Wevers, Birgit Obermeier, Graham Marsh, Karlijn Wilschut, Yasuteru Sano, Sebastiaan Johannes Trietsch, Henriëtte L. Lanz, Takashi Kanda, Dhanesh G. Kasi, Fumitaka Shimizu
Publikováno v:
Fluids and Barriers of the CNS
Fluids and Barriers of the CNS, Vol 15, Iss 1, Pp 1-12 (2018)
Fluids and Barriers of the CNS, Vol 15, Iss 1, Pp 1-12 (2018)
Background Receptor-mediated transcytosis is one of the major routes for drug delivery of large molecules into the brain. The aim of this study was to develop a novel model of the human blood–brain barrier (BBB) in a high-throughput microfluidic de
Autor:
Junmei Cairns, Richard M. Weinshilboum, Paul Vulto, Jia Yu, Jos Joore, Bart Kramer, Chee Ping Ng, Liewei Wang, Thomas Hankemeier, Sebastiaan Johannes Trietsch, Henriëtte L. Lanz, Anthony D. Saleh
Publikováno v:
BMC Cancer, 17, 709
BMC Cancer, Vol 17, Iss 1, Pp 1-11 (2017)
BMC Cancer
BMC Cancer, Vol 17, Iss 1, Pp 1-11 (2017)
BMC Cancer
Background Breast cancer is the most common invasive cancer among women. Currently, there are only a few models used for therapy selection, and they are often poor predictors of therapeutic response or take months to set up and assay. In this report,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fddf5fd4ce31ea99f92112249acca819
http://hdl.handle.net/1887/58311
http://hdl.handle.net/1887/58311
Autor:
Paul Vulto, Sebastiaan Johannes Trietsch, Jos Joore, Henriëtte L. Lanz, Arnaud Nicolas, Adrian Roth, Stefan Kustermann, Marianne K. Vormann, Karlijn Wilschut, Annie Moisan, Meily C. Setyawati, Elena Naumovska, Dorota Kurek, Thomas Hankemeier, Chee Ping Ng
Publikováno v:
Nature Communications
Nature Communications, 8, 262
Nature Communications, Vol 8, Iss 1, Pp 1-8 (2017)
Nature Communications, 8, 262
Nature Communications, Vol 8, Iss 1, Pp 1-8 (2017)
In vitro models that better reflect in vivo epithelial barrier (patho-)physiology are urgently required to predict adverse drug effects. Here we introduce extracellular matrix-supported intestinal tubules in perfused microfluidic devices, exhibiting
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::14d5649c1feafc0495e999166c554ef5
https://hdl.handle.net/1887/56868
https://hdl.handle.net/1887/56868
Autor:
Henriëtte L. Lanz, Sebastiaan Johannes Trietsch, Paul Vulto, Jos Joore, Chiwan Chiang, Nienke R. Wevers, Karlijn Wilschut, Arnaud Nicolas, Remko van Vught
Publikováno v:
Scientific Reports
With great advances in the field of in vitro brain modelling, the challenge is now to implement these technologies for development and evaluation of new drug candidates. Here we demonstrate a method for culturing three-dimensional networks of spontan
Autor:
Karlijn Wilschut, Nienke R. Wevers, Xandor M Spijkers, Sebastiaan Johannes Trietsch, Remko van Vught, John Lowman, Paul Vulto
Publikováno v:
Drug Metabolism and Pharmacokinetics. 34:S54
Autor:
John Lowman, Paul Vulto, Remko van Vught, Sebastiaan Johannes Trietsch, Henriëtte L. Lanz, Karlijn Wilschut, Annie Moisan, Elena Naumovska, Dorota Kurek, Arnaud Nicolas, Adrian Roth, Stefan Kustermann
Publikováno v:
Drug Metabolism and Pharmacokinetics. 34:S54
Autor:
Henriëtte L. Lanz, Sebastiaan Johannes Trietsch, Anthony D. Saleh, Jos Joore, Linda Gijzen, Paul Vulto, Marianne K. Vormann, Remko van Vught
Publikováno v:
Drug Metabolism and Pharmacokinetics. 34:S55
Autor:
Arnaud Nicolas, C. Chang, Henriëtte L. Lanz, T. Olivier, Sebastiaan Johannes Trietsch, C. Ramakers, Karlijn Wilschut
Publikováno v:
Toxicology Letters. 295:S126
Autor:
Rosalinde Masereeuw, Laura Suter-Dick, Martijn J. Wilmer, Marianne K. Vormann, Henriëtte L. Lanz, Simon Hutter, Jos Joore, Linda Gijzen, Sebastiaan Johannes Trietsch, Jelle Vriend
Publikováno v:
Toxicology Letters. 295:S68
Publikováno v:
Current Opinion in Biotechnology, 35, 118-126
The transition from 2D to 3D cell culture techniques is an important step in a trend towards better biomimetic tissue models. Microfluidics allows spatial control over fluids in micrometer-sized channels has become a valuable tool to further increase