Výsledky vyhledávání - "Sebastiaan J Hullegie"

Akademický článek

Early treatment of acute hepatitis C infection is cost-effective in HIV-infected men-who-have-sex-with-men.

Autor: Stephanie Popping, Sebastiaan J Hullegie, Anne Boerekamps, Bart J A Rijnders, Robert J de Knegt, Jürgen K Rockstroh, Annelies Verbon, Charles A B Boucher, Brooke E Nichols, David A M C van de Vijver

Publikováno v: PLoS ONE, Vol 14, Iss 1, p e0210179 (2019)

BackgroundTreatment of hepatitis C virus infections (HCV) with direct acting antivirals (DAA) can prevent new infections since cured individuals cannot transmit HCV. However, as DAAs are expensive, many countries defer treatment to advances stages of

Externí odkaz: https://doaj.org/article/9cf3a1db260f4a0d9cfbe1ea5cae48ba

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Akademický článek

Frequencies of Circulating MAIT Cells Are Diminished in Chronic HCV, HIV and HCV/HIV Co-Infection and Do Not Recover during Therapy.

Autor: Michelle Spaan, Sebastiaan J Hullegie, Boris J B Beudeker, Kim Kreefft, Gertine W van Oord, Zwier M A Groothuismink, Marjolein van Tilborg, Bart Rijnders, Robert J de Knegt, Mark A A Claassen, Andre Boonstra

Publikováno v: PLoS ONE, Vol 11, Iss 7, p e0159243 (2016)

Mucosal-associated invariant T (MAIT) cells comprise a subpopulation of T cells that can be activated by bacterial products and cytokines to produce IFN-γ. Since little is known on MAIT cells during HCV infection, we compared their phenotype and fun

Externí odkaz: https://doaj.org/article/ceeec7d7dbc8492488ce103792aa7e08

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The REMAP-CAP (Randomized Embedded Multifactorial Adaptive Platform for Community-acquired Pneumonia) Study. Rationale and Design

Publikováno v: Annals of the American Thoracic Society
Annals of the American Thoracic Society, vol 17, iss 7
Proceedings of the American Thoracic Society
Annals of the American Thoracic Society, 17(7), 879-891. American Thoracic Society

There is broad interest in improved methods to generate robust evidence regarding best practice, especially in settings where patient conditions are heterogenous and require multiple concomitant therapies. Here, we present the rationale and design of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c8e6034412888a3fc7b082650d30eb1b
https://doi.org/10.1513/annalsats.202003-192sd

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PROPHETIC EU: Prospective Identification of Pneumonia in Hospitalized Patients in the Intensive Care Unit in European and United States Cohorts

Publikováno v: Dipòsit Digital de la UB
Universidad de Barcelona
Open Forum Infectious Diseases, 9(7):231, 1-10. Oxford University Press

Background The prospective identification of patients at high risk for hospital-acquired/ventilator-associated bacterial pneumonia may improve clinical trial feasibility and foster antibacterial development. In a prior study conducted in the United S

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8db74b601efc9f2075f4c0fcc4a8f02a
http://hdl.handle.net/2445/187982

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Prophetic EU: Prospective Identification of Pneumonia in Hospitalized Patients in the Intensive Care Unit–A Comparison of European and United States Cohorts

Publikováno v: SSRN Electronic Journal.

Background: Prospective identification of patients at high risk of nosocomial pneumonia may improve clinical trial feasibility and foster antibacterial development. Clinical criteria prospectively identified patients at highest risk of hospital-acqui

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::aae5d70fcf622e30630fce4fc4d701c9
https://doi.org/10.2139/ssrn.3907471

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Boceprevir, peginterferon and ribavirin for acute hepatitis C in HIV infected patients

Autor: Astrid M. Newsum, Sebastiaan J. Hullegie, Bart J. A. Rijnders, F. N. Lauw, Jan van der Meer, Mark A. A. Claassen, Joop E. Arends, Dirk Posthouwer, Arne van Eeden, Peter P. Koopmans, Wouter F W Bierman, Eliane M. S. Leyten, Guido E.L. van den Berk, Clemens Richter

Publikováno v: Journal of Hepatology, 64(4), 807-812. Elsevier Science
Journal of Hepatology, 64, 4, pp. 807-12
Journal of Hepatology, 64, 807-12
Journal of hepatology, 64(4), 807-812. Elsevier
Journal of Hepatology, 64(4), 807-812. ELSEVIER SCIENCE BV

Background & Aims: Acute hepatitis C virus infections (AHCV) are prevalent among HIV positive men having sex with men and generally treated with pegylated interferon-alpha (PegIFN) and ribavirin (RBV) during 24 weeks. The addition of a protease inhib

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::14d990698bc3d0b842e4b8df7527c7be
https://doi.org/10.1016/j.jhep.2015.12.004

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Early treatment of acute hepatitis C infection is cost-effective in HIV-infected men-who-have-sex-with-men

Autor: David A. M. C. van de Vijver, Robert J. de Knegt, Sebastiaan J. Hullegie, Anne Boerekamps, Stephanie Popping, Bart J. A. Rijnders, Jürgen K. Rockstroh, Charles A. Boucher, Brooke E Nichols, Annelies Verbon

Publikováno v: PLoS ONE
PLoS One (online), 14(1):e0210179. Public Library of Science
PLoS ONE, Vol 14, Iss 1, p e0210179 (2019)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b678c7aa4a0dd67e5e8792dcb9adea7f
https://pubmed.ncbi.nlm.nih.gov/30629662

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Declining Hepatitis C Virus (HCV) Incidence in Dutch Human Immunodeficiency Virus-Positive Men Who Have Sex With Men After Unrestricted Access to HCV Therapy

Publikováno v: Boerekamps, A, van den Berk, G E, Lauw, F N, Leyten, E M, van Kasteren, M E, van Eeden, A, Posthouwer, D, Claassen, M A, Dofferhoff, A S, Verhagen, D W M, Bierman, W F, Lettinga, K D, Kroon, F P, Delsing, C E, Groeneveld, P H, Soetekouw, R, Peters, E J, Hullegie, S J, Popping, S, van de Vijver, D A M C, Boucher, C A, Arends, J E & Rijnders, B J 2018, ' Declining Hepatitis C Virus (HCV) Incidence in Dutch Human Immunodeficiency Virus-Positive Men Who Have Sex With Men After Unrestricted Access to HCV Therapy ', Clinical Infectious Diseases, vol. 66, no. 9, pp. 1360-1365 . https://doi.org/10.1093/cid/cix1007, https://doi.org/10.1093/cid/cix1007
Clinical Infectious Diseases, 66(9), 1360-1365
Clinical Infectious Diseases, 66(9), 1360-1365. Oxford University Press
Clinical Infectious Diseases, 66, 1360-1365
Clinical Infectious Diseases, 66, 9, pp. 1360-1365

Background. Direct-acting antivirals (DAAa) cure hepatitis C virus (HCV) infections in 95% of infected patients. Modeling studies predict that universal HCV treatment will lead to a decrease in the incidence of new infections but real-life data are l

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b294746e56b813219ab13936a335d4a1
https://research.vumc.nl/en/publications/15cccc8b-4443-422a-841b-61ca5f1ba21e

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HCV antigen instead of RNA testing to diagnose acute HCV in patients treated in the Dutch Acute HCV in HIV Study

Autor: Annemiek A. van der Eijk, Chris Ramakers, Corine H. GeurtsvanKessel, Bart J. A. Rijnders, Sebastiaan J. Hullegie

Publikováno v: Journal of the International AIDS Society
Journal of the International AIDS Society, 20:21621. John Wiley & Sons Inc.

Introduction : Affordable and sensitive screening methods for acute hepatitis C (HCV) are necessary to successfully intervene in the current HCV epidemic among HIV-positive men having sex with men. HCV core antigen (Ag) testing has been proven effect

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c6b0f5009fb072f2794b4d5aa823b83
https://hdl.handle.net/1765/103471

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