Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Sebastiaan G. J. M. Kluijtmans"'
Follistatin Effects in Migration, Vascularization, and Osteogenesis in vitro and Bone Repair in vivo
Autor:
Shorouk Fahmy-Garcia, Eric Farrell, Janneke Witte-Bouma, Iris Robbesom-van den Berge, Melva Suarez, Didem Mumcuoglu, Heike Walles, Sebastiaan G. J. M. Kluijtmans, Bram C. J. van der Eerden, Gerjo J. V. M. van Osch, Johannes P. T. M. van Leeuwen, Marjolein van Driel
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 7 (2019)
The use of biomaterials and signaling molecules to induce bone formation is a promising approach in the field of bone tissue engineering. Follistatin (FST) is a glycoprotein able to bind irreversibly to activin A, a protein that has been reported to
Externí odkaz:
https://doaj.org/article/1830ea159d7944d4bdf76f7fa8e5daed
Autor:
Sebastiaan G. J. M. Kluijtmans, Joachim Nickel, Shehrazade Jekhmane, Didem Mumcuoglu, Claudia Siverino, Johannes P.T.M. van Leeuwen, Gerjo J.V.M. van Osch, Thomas D. Mueller, Laura de Miguel
Publikováno v:
Materials Science & Engineering C-Biomimetic Materials Sensors and Systems, 84, 271-280. Elsevier
Bone morphogenetic protein-2 (BMP-2) is a powerful osteoinductive protein; however, there is a need for the development of a safe and efficient BMP-2 release system for bone regeneration therapies. Recombinant extracellular matrix proteins are promis
Publikováno v:
ACS Biomaterials Science & Engineering. 3:1100-1108
Biomineralized scaffolds are an attractive option for bone tissue engineering, being similar to native bone. However, optimization is difficult, due to the complex interplay among architecture, chemistry, and mechanics. Utilizing biomimetic nucleatio
Autor:
Heike Walles, Davide Confalonieri, Kendell M. Pawelec, Sebastiaan G. J. M. Kluijtmans, Huibert A. van Boxtel, Franziska Ehlicke
Publikováno v:
Journal of Biomedical Materials Research Part A. 105:1856-1866
Recombinant peptides have the power to harness the inherent biocompatibility of natural macromolecules, while maintaining a defined chemistry for use in tissue engineering. Creating scaffolds from peptides requires stabilization via crosslinking, a p
Autor:
Shorouk, Fahmy-Garcia, Eric, Farrell, Janneke, Witte-Bouma, Iris, Robbesom-van den Berge, Melva, Suarez, Didem, Mumcuoglu, Heike, Walles, Sebastiaan G J M, Kluijtmans, Bram C J, van der Eerden, Gerjo J V M, van Osch, Johannes P T M, van Leeuwen, Marjolein, van Driel
Publikováno v:
Frontiers in Bioengineering and Biotechnology
The use of biomaterials and signaling molecules to induce bone formation is a promising approach in the field of bone tissue engineering. Follistatin (FST) is a glycoprotein able to bind irreversibly to activin A, a protein that has been reported to
Autor:
Carolina A. F. M. van Speuwel-Goossens, Martin C. Harmsen, Mojtaba Parvizi, Sebastiaan G. J. M. Kluijtmans, Josee A. Plantinga, Elisabeth M. W. M. van Dongen
Publikováno v:
Journal of Biomedical Materials Research Part A. 104:503-516
Stem cell therapy is a promising approach for repair, remodeling and even regenerate tissue of otherwise irreparable damage, such as after myocardial infarction (aMI). A severe limitation of cardiac stem cell therapy is the generally poor retention o
Autor:
J Nicke, Didem Mumcuoglu, Eric Farrell, Shorouk Fahmy-Garcia, Sebastiaan G. J. M. Kluijtmans, Yanto Ridwan, G.J.V.M. van Osch
Publikováno v:
European Cells & Materials, Vol 35, Pp 242-254 (2018)
European cells & materials, 35, 242-254. AO Research Institute
European cells & materials, 35, 242-254. AO Research Institute
The aim of the current study was to reduce the clinically used supra-physiological dose of bone morphogenetic protein-2 (BMP-2) (usually 1.5 mg/mL), which carries the risk of adverse events, by using a more effective release system. A slow release sy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c241b1294ab382593952ef4b4d4e3d11
https://publica.fraunhofer.de/handle/publica/255047
https://publica.fraunhofer.de/handle/publica/255047
Publikováno v:
Materials scienceengineering. C, Materials for biological applications. 81
Publikováno v:
Materials scienceengineering. C, Materials for biological applications. 76
Nutrient diffusion and cellular infiltration are important factors for tissue engineering scaffolds. Maximizing both, by optimizing permeability and scaffold architecture, is important to achieve functional recovery. The relationship between scaffold
Autor:
Sebastiaan G. J. M. Kluijtmans, Martin C. Harmsen, Annemarie Tuin, Marja J. A. van Luyn, Jan Bastiaan Bouwstra
Publikováno v:
Tissue Engineering. Part A, 16(6), 1811-1821. MARY ANN LIEBERT, INC
Microspheres (MSs) can function as multifunctional scaffolds in different approaches of tissue repair (TR), as a filler, a slow-release depot for growth factors, or a delivery vehicle for cells. Natural cell adhesion-supporting extracellular matrix c