Design, Synthesis, Characterization, and Evaluation of the Anti-HT-29 Colorectal Cell Line Activity of Novel 8-Oxyquinolinate-Platinum(II)-Loaded Nanostructured Lipid Carriers Targeted with Riboflavin

Autor: Tugce Boztepe, Sebastián Scioli-Montoto, Rocio C. Gambaro, María Esperanza Ruiz, Silvia Cabrera, José Alemán, Germán A. Islan, Guillermo R. Castro, Ignacio E. León

Publikováno v: Pharmaceutics, Vol 15, Iss 3, p 1021 (2023)

Colorectal cancer is occasionally called colon or rectal cancer, depending on where cancer begins to form, and is the second leading cause of cancer death among both men and women. The platinum-based [PtCl(8-O-quinolinate)(dmso)] (8-QO-Pt) compound h

Externí odkaz: https://doaj.org/article/84c9671505cb41749958d37652d414bd

Influence of rheological properties and microstructure of microemulsions on the kinetic release of bioactive compounds

Autor: Noelia Mori Cortés, Sebastián Scioli Montoto, María Esperanza Ruiz, Alicia Califano, Gabriel Lorenzo

Microemulsions (ME) are one of the most effective ways to incorporate lipophilic active compounds into water-based food matrices. Great stability, colloidal domain droplets, and optical isotropy are some of the ME advantages. The present work analyze

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::8bbac2eb963703eb63fe13ded58c5696
https://doi.org/10.21203/rs.3.rs-1631014/v1

Solid Lipid Nanoparticles for Drug Delivery: Pharmacological and Biopharmaceutical Aspects

Autor: Sebastián Scioli Montoto, Giuliana Muraca, María Esperanza Ruiz

Publikováno v: CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
Frontiers in Molecular Biosciences, Vol 7 (2020)
Frontiers in Molecular Biosciences

In the golden age of pharmaceutical nanocarriers, we are witnessing a maturation stage of the original concepts and ideas. There is no doubt that nanoformulations are extremely valuable tools for drug delivery applications; the current challenge is h

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::47edd6b719260888fb6f9d4b385fc8cf
https://doi.org/10.3389/fmolb.2020.587997

Hybrid Ofloxacin/eugenol co-loaded solid lipid nanoparticles with enhanced and targetable antimicrobial properties

Autor: M. Di Ianni, Vera Alejandra Alvarez, German Abel Islan, Sebastián Scioli Montoto, María Laura Sbaraglini, María Esperanza Ruiz, Alan Talevi, Boris Rodenak-Kladniew, Nelson Durán, Guillermo R. Castro

Publikováno v: International journal of pharmaceutics. 569

In the global context of an imminent emergence of multidrug-resistant microorganisms, the present work combined the use of nanotechnology and the therapeutic benefits of natural compounds as a strategy to potentiateantimicrobial action of the wide-sp

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e9a78021ff14cc4cd5625aa29d8e827
https://pubmed.ncbi.nlm.nih.gov/31356956

Carbamazepine-loaded solid lipid nanoparticles and nanostructured lipid carriers: Physicochemical characterization and in vitro/in vivo evaluation

Autor: Manuel Couyoupetrou, María Laura Sbaraglini, Alan Talevi, Guido Pesce, Guillermo R. Castro, María Esperanza Ruiz, Vera Alejandra Alvarez, M. Di Ianni, German Abel Islan, Luis E. Bruno-Blanch, Sebastián Scioli Montoto

Publikováno v: Colloids and surfaces. B, Biointerfaces. 167

Solid lipid nanoparticles (SLN) and nanostructured lipid carriers (NLC) represent promising alternatives for drug delivery to the central nervous system. In the present work, four different nanoformulations of the antiepileptic drug Carbamazepine (CB

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::caf183ee05f2ebd697876b1e5baefcfe
https://pubmed.ncbi.nlm.nih.gov/29627680