Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Sebastián Amigorena"'
Autor:
Fernando Erra Díaz, Valeria Ochoa, Antonela Merlotti, Ezequiel Dantas, Ignacio Mazzitelli, Virginia Gonzalez Polo, Juan Sabatté, Sebastián Amigorena, Elodie Segura, Jorge Geffner
Publikováno v:
Cell Reports, Vol 31, Iss 5, Pp - (2020)
Summary: During inflammation, recruited monocytes can differentiate either into macrophages or dendritic cells (DCs); however, little is known about the environmental factors that determine this cell fate decision. Low extracellular pH is a hallmark
Externí odkaz:
https://doaj.org/article/8d33be740002440bb4e26068d0228438
Autor:
Antonela Merlotti, Alvaro López Malizia, Paula Michea, Pierre-Emmanuel Bonte, Christel Goudot, María Sol Carregal, Nicolás Nuñez, Christine Sedlik, Ana Ceballos, Vassili Soumelis, Sebastián Amigorena, Jorge Geffner, Eliane Piaggio, Juan Sabatte
Publikováno v:
OncoImmunology, Vol 8, Iss 9 (2019)
Clusterin is a glycoprotein able to mediate different physiological functions such as control of complement activation, promotion of unfolded protein clearance and modulation of cell survival. Clusterin is overexpressed in many types of cancers and a
Externí odkaz:
https://doaj.org/article/ed6af3dd03db4854bd7c25864e4a15d6
Autor:
Alvaro López Malizia, Antonela Merlotti, Pierre-Emmanuel Bonte, Melina Sager, Yago Arribas De Sandoval, Christel Goudot, Fernando Erra Díaz, Pehuén Pereyra-Gerber, Ana Ceballos, Sebastian Amigorena, Jorge Geffner, Juan Sabatte
Publikováno v:
OncoImmunology, Vol 13, Iss 1 (2024)
ABSTRACTDendritic cells (DCs) play a key role in the induction of the adaptive immune response. They capture antigens in peripheral tissues and prime naïve T lymphocytes, triggering the adaptive immune response. In the course of inflammatory process
Externí odkaz:
https://doaj.org/article/beaaab2a205c43428fb0b3caaa69dd36
Autor:
Manuel Rodrigues, Giulia Vanoni, Pierre Loap, Coraline Dubot, Eleonora Timperi, Mathieu Minsat, Louis Bazire, Catherine Durdux, Virginie Fourchotte, Enora Laas, Nicolas Pouget, Zahra Castel-Ajgal, Gregoire Marret, Laetitia Lesage, Didier Meseure, Anne Vincent-Salomon, Lolita Lecompte, Nicolas Servant, Sophie Vacher, Ivan Bieche, Caroline Malhaire, Virginie Huchet, Laurence Champion, Maud Kamal, Sebastian Amigorena, Olivier Lantz, Marion Chevrier, Emanuela Romano
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-15 (2023)
Abstract Concurrent chemoradiotherapy (CRT) with blockade of the PD-1 pathway may enhance immune-mediated tumor control through increased phagocytosis, cell death, and antigen presentation. The NiCOL phase 1 trial (NCT03298893) is designed to determi
Externí odkaz:
https://doaj.org/article/ae19c89ecebf4147acfd3e5c2acc5362
Autor:
Leticia Laura Niborski, Paul Gueguen, Mengliang Ye, Allan Thiolat, Rodrigo Nalio Ramos, Pamela Caudana, Jordan Denizeau, Ludovic Colombeau, Raphaël Rodriguez, Christel Goudot, Jean-Michel Luccarini, Anne Soudé, Bruno Bournique, Pierre Broqua, Luigia Pace, Sylvain Baulande, Christine Sedlik, Jean-Pierre Quivy, Geneviève Almouzni, José L. Cohen, Elina Zueva, Joshua J. Waterfall, Sebastian Amigorena, Eliane Piaggio
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-16 (2022)
Abstract Tumor-infiltrating CD8 + T cells progressively lose functionality and fail to reject tumors. The underlying mechanism and re-programing induced by checkpoint blockers are incompletely understood. We show here that genetic ablation or pharmac
Externí odkaz:
https://doaj.org/article/22bfa2b345944a4983ce8b49f08339e4
Autor:
Lucía Biscari, Ma Carmen Maza, Cecilia Farré, Cintia Daniela Kaufman, Sebastian Amigorena, Manuel Fresno, Núria Gironès, Andrés Alloatti
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 11 (2023)
Antigen cross-presentation is a vital mechanism of dendritic cells and other antigen presenting cells to orchestrate the priming of cytotoxic responses towards killing of infected or cancer cells. In this process, exogenous antigens are internalized
Externí odkaz:
https://doaj.org/article/60e4238fe43948da8ba96cb746ee014e
Autor:
Leticia Laura Niborski, Paul Gueguen, Mengliang Ye, Allan Thiolat, Rodrigo Nalio Ramos, Pamela Caudana, Jordan Denizeau, Ludovic Colombeau, Raphaël Rodriguez, Christel Goudot, Jean-Michel Luccarini, Anne Soudé, Bruno Bournique, Pierre Broqua, Luigia Pace, Sylvain Baulande, Christine Sedlik, Jean-Pierre Quivy, Geneviève Almouzni, José L. Cohen, Elina Zueva, Joshua J. Waterfall, Sebastian Amigorena, Eliane Piaggio
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-1 (2023)
Externí odkaz:
https://doaj.org/article/103f997df819424ea57c7cf97b5024dc
Publikováno v:
Immunity. 20(1)
A recent workshop on "Dendritic Cells: Biology and Therapeutic Applications," sponsored by the Juan March Foundation, brought together basic and clinical research scientists to discuss the mechanisms underlying the control of immune responses and tol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::7aabe685ecb790dbee1148b35464de57
https://pubmed.ncbi.nlm.nih.gov/14738761
https://pubmed.ncbi.nlm.nih.gov/14738761
Autor:
Nicolas Gonzalo Núñez, Jimena Tosello Boari, Rodrigo Nalio Ramos, Wilfrid Richer, Nicolas Cagnard, Cyrill Dimitri Anderfuhren, Leticia Laura Niborski, Jeremy Bigot, Didier Meseure, Philippe De La Rochere, Maud Milder, Sophie Viel, Delphine Loirat, Louis Pérol, Anne Vincent-Salomon, Xavier Sastre-Garau, Becher Burkhard, Christine Sedlik, Olivier Lantz, Sebastian Amigorena, Eliane Piaggio
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-15 (2020)
Tumor-draining lymph nodes are often the first site of metastasis in breast cancer patients. Here, the authors show that metastatic lymph nodes are characterized by the accumulation of suppressive regulatory T cells with a distinct phenotype compared
Externí odkaz:
https://doaj.org/article/fa92c2f7fbcd485fb13c6e8b461e9fce
Autor:
Carol Haddoub, Mohamad Rima, Sandrine Heurtebise, Myriam Lawand, Dania Jundi, Riyad Sadek, Sebastian Amigorena, Ziad Fajloun, Marc C. Karam
Publikováno v:
PeerJ, Vol 8, p e9909 (2020)
Background Montivipera bornmuelleri’s venom has shown immunomodulation of cytokines release in mice and selective cytotoxicity on cancer cells in a dose-dependent manner, highlighting an anticancer potential. Here, we extend these findings by eluci
Externí odkaz:
https://doaj.org/article/4018b147c8dd4467b5214f7211f43929