An engineered prodrug selectively suppresses β-lactam resistant bacteria in a mixed microbial setting.

Autor: Duda AM; Department of Chemistry, Duke University, Durham, NC 27710, USA., Ma HR; Department of Biomedical Engineering, Duke University, Durham, NC 27710, USA., Villalobos CA; Department of Biomedical Engineering, Duke University, Durham, NC 27710, USA., Kuhn SA; Department of Chemistry, Duke University, Durham, NC 27710, USA., He K; Department of Biomedical Engineering, Duke University, Durham, NC 27710, USA., Seay SR; Department of Chemistry, Duke University, Durham, NC 27710, USA., Jackson AC; Department of Chemistry, Duke University, Durham, NC 27710, USA., Suh CM; Department of Chemistry, Duke University, Durham, NC 27710, USA., Puccio EA; Department of Chemistry, Duke University, Durham, NC 27710, USA., Anderson DJ; Division of Infectious Diseases, Department of Medicine, Duke University, Durham, NC 27710, USA., Fowler VG Jr; Division of Infectious Diseases, Department of Medicine, Duke University, Durham, NC 27710, USA., You L; Department of Biomedical Engineering, Duke University, Durham, NC 27710, USA., Franz KJ; Department of Chemistry, Duke University, Durham, NC 27710, USA.

Publikováno v: BioRxiv : the preprint server for biology [bioRxiv] 2024 Aug 03. Date of Electronic Publication: 2024 Aug 03.