Receptor tyrosine kinase inhibition leads to regression of acral melanoma by targeting the tumor microenvironment.

Autor: Smith EA; Department of Pathology, University of Utah, Salt Lake City, UT, USA., Belote RL; The Huntsman Cancer Institute, University of Utah, Salt Lake City, UT, USA.; Department of Molecular Genetics, The Ohio State University, Columbus, OH, USA., Cruz NM; Department of Cancer Biology and Genetics, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Moustafa TE; Department of Chemical Engineering, University of Utah, Salt Lake City, UT, USA., Becker CA; Department of Dermatology, University of Utah, Salt Lake City, UT, USA., Jiang A; Department of Oncological Sciences, University of Utah, Salt Lake City, UT, USA., Alizada S; Department of Chemical Engineering, University of Utah, Salt Lake City, UT, USA., Chan TY; Preclinical Research Resource, Huntsman Cancer Institute, University of Utah, Salt Lake City, UT, USA., Seasor TA; Department of Pathology, University of Utah, Salt Lake City, UT, USA., Balatico M; Department of Pathology, University of Utah, Salt Lake City, UT, USA., Cortes-Sanchez E; Immuno Oncology Network Core, The Huntsman Cancer Institute, University of Utah, Salt Lake City, UT, USA.; Department of Surgery, University of Utah School of Medicine, Salt Lake City, UT, USA., Lum DH; Preclinical Research Resource, Huntsman Cancer Institute, University of Utah, Salt Lake City, UT, USA., Hyngstrom JR; The Huntsman Cancer Institute, University of Utah, Salt Lake City, UT, USA.; Department of Surgery, University of Utah School of Medicine, Salt Lake City, UT, USA., Zeng H; Department of Oncology, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.; Shanghai Institute of Precision Medicine, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China., Deacon DC; The Huntsman Cancer Institute, University of Utah, Salt Lake City, UT, USA.; Department of Dermatology, University of Utah, Salt Lake City, UT, USA., Grossmann AH; Department of Pathology, University of Utah, Salt Lake City, UT, USA.; The Huntsman Cancer Institute, University of Utah, Salt Lake City, UT, USA., White RM; Department of Cancer Biology and Genetics, Memorial Sloan Kettering Cancer Center, New York, NY, USA.; Ludwig Cancer Research, Nuffield Department of Medicine, University of Oxford, Oxford UK., Zangle TA; The Huntsman Cancer Institute, University of Utah, Salt Lake City, UT, USA.; Department of Chemical Engineering, University of Utah, Salt Lake City, UT, USA., Judson-Torres RL; The Huntsman Cancer Institute, University of Utah, Salt Lake City, UT, USA.; Department of Dermatology, University of Utah, Salt Lake City, UT, USA.; Department of Oncological Sciences, University of Utah, Salt Lake City, UT, USA.

Publikováno v: BioRxiv : the preprint server for biology [bioRxiv] 2024 Jun 17. Date of Electronic Publication: 2024 Jun 17.