Výsledky vyhledávání - "Sean Z Hutchinson"

Akademický článek

Adiponectin alleviates genioglossal mitochondrial dysfunction in rats exposed to intermittent hypoxia.

Autor: Hanpeng Huang, Xiufeng Jiang, Yanbin Dong, Xiaofeng Zhang, Ning Ding, Jiannan Liu, Sean Z Hutchinson, Gan Lu, Xilong Zhang

Publikováno v: PLoS ONE, Vol 9, Iss 10, p e109284 (2014)

Genioglossal dysfunction is involved in the pathophysiology of obstructive sleep apnea hypoxia syndrome (OSAHS) characterized by nocturnal chronic intermittent hypoxia (CIH). The pathophysiology of genioglossal dysfunction and possible targeted pharm

Externí odkaz: https://doaj.org/article/a544de2bf0a949c4907021af1aa85055

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Akademický článek

Adiponectin protects rat myocardium against chronic intermittent hypoxia-induced injury via inhibition of endoplasmic reticulum stress.

Autor: Wenxiao Ding, Xiaofeng Zhang, Hanpeng Huang, Ning Ding, Shijiang Zhang, Sean Z Hutchinson, Xilong Zhang

Publikováno v: PLoS ONE, Vol 9, Iss 4, p e94545 (2014)

Obstructive sleep apnea syndrome (OSAS) is associated with many cardiovascular disorders such as heart failure, hypertension, atherosclerosis, and arrhythmia and so on. Of the many associated factors, chronic intermittent hypoxia (CIH) in particular

Externí odkaz: https://doaj.org/article/2fa7d56550cf427280509d66b763364d

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Vitamin E δ-tocotrienol sensitizes human pancreatic cancer cells to TRAIL-induced apoptosis through proteasome-mediated down-regulation of c-FLIPs

Autor: Surinder K. Batra, Said M. Sebti, Sean Z. Hutchinson, Mokenge P. Malafa, Rony A. Francois, Chen Wang, Michael Kongnyuy, Anying Zhang, Domenico Coppola, Kazim Husain

Publikováno v: Cancer Cell International, Vol 19, Iss 1, Pp 1-15 (2019)
Cancer Cell International

Background Vitamin E δ-tocotrienol (VEDT), a vitamin E compound isolated from sources such as palm fruit and annatto beans, has been reported to have cancer chemopreventive and therapeutic effects. Methods We report a novel function of VEDT in augme

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f30c94db2fe7d1ca573c797984e7b10
https://doi.org/10.1186/s12935-019-0876-0

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External beam radiation therapy and a low-dose-rate brachytherapy boost without or with androgen deprivation therapy for prostate cancer

Autor: Nicholas B Figura, Alex Cruz, Richard B. Wilder, Tobin Strom, Kevin Nethers, Sean Z. Hutchinson, Kushagra Shrinath, Matthew C. Biagioli, Randy V. Heysek, Daniel C. Fernandez

Publikováno v: International Brazilian Journal of Urology, Vol 40, Iss 4, Pp 474-483 (2014)
International braz j urol, Volume: 40, Issue: 4, Pages: 474-483, Published: AUG 2014
International braz j urol v.40 n.4 2014
International Braz J Urol
Sociedade Brasileira de Urologia (SBU)
instacron:SBU

Purpose To assess outcomes with external beam radiation therapy (EBRT) and a low-dose-rate (LDR) brachytherapy boost without or with androgen deprivation therapy (ADT) for prostate cancer. Materials and Methods From January 2001 through August 2011,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::479659a03f37984e3d612f9f4463dc63
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1677-55382014000400474&lng=en&tlng=en

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Elimination of central sleep apnea by cardiac valve replacement: a continuous follow-up study in patients with rheumatic valvular heart disease

Autor: Wang Jian Zha, Ning Ding, Xi Long Zhang, Mao Huang, Wei Lin, Hong Wang, Shi Jiang Zhang, Bu Qing Ni, Sean Z. Hutchinson

Publikováno v: Sleep Medicine. 15:880-886

Background Recent studies have suggested that cardiac surgery may affect sleep-disordered breathing (SDB) in chronic heart failure patients. However, the dynamic changes in sleep apnea and heart function after cardiac surgery and the mechanisms respo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fa1ca8ad2a2b5de69ede8dee7b581bb0
https://doi.org/10.1016/j.sleep.2014.02.007

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Adiponectin protects the rats liver against chronic intermittent hypoxia induced injury through AMP-activated protein kinase pathway

Autor: Xilong Zhang, Qiang Zhang, Ning Ding, Hanpeng Huang, Wen-Xiao Ding, Xianji Zhu, Yanbin Dong, Sean Z. Hutchinson, Xingya Gao

Publikováno v: Scientific Reports

This study was performed to assess the effect of chronic intermittent hypoxia (CIH) on the liver, the associated mechanisms and the potential therapeutic roles of adiponectin (Ad). Sixty rats were randomly assigned to four groups: the normal control

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e8722a9cde59af6bc937eec46a7fff0

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Vitamin E δ-Tocotrienol Levels in Tumor and Pancreatic Tissue of Mice after Oral Administration

Autor: Sean Z. Hutchinson, Domenico Coppola, Richard Lush, Anthony Neuger, Said M. Sebti, Rony A. Francois, Mokenge P. Malafa, Kazim Husain

Publikováno v: Pharmacology. 83:157-163

Tocotrienols are natural vitamin E compounds that are known to have a neuroprotective effect at nanomolar concentration and anti-carcinogenic effect at micromolar concentration. In this report, we investigated the pharmacokinetics, tumor and pancreat

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c1ca74ec5979c87c73899a07bc4ec86
https://doi.org/10.1159/000190792

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Pancreatic Tissue Distribution, Pharmacokinetics and Toxicity of Bioactive delta‐tocotrienol, a Potential Anti‐tumor Bioactive Food Component, in Mice

Autor: Sean Z. Hutchinson, Mokenge P. Malafa, Anthony Neuger, Rony A. Francois, Said M. Sebti, Richard Lush, Kazim Husain

Publikováno v: The FASEB Journal. 22

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::363a1d2edddf8a300f3464e9e7f1598f
https://doi.org/10.1096/fasebj.22.1_supplement.922.3

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Adiponectin Alleviates Genioglossal Mitochondrial Dysfunction in Rats Exposed to Intermittent Hypoxia

Autor: Jiannan Liu, Hanpeng Huang, Xiufeng Jiang, Yanbin Dong, Xilong Zhang, Xiaofeng Zhang, Ning Ding, Gan Lu, Sean Z. Hutchinson

Publikováno v: PLoS ONE
PLoS ONE, Vol 9, Iss 10, p e109284 (2014)

Background Genioglossal dysfunction is involved in the pathophysiology of obstructive sleep apnea hypoxia syndrome (OSAHS) characterized by nocturnal chronic intermittent hypoxia (CIH). The pathophysiology of genioglossal dysfunction and possible tar

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07916e76e1e52bdffbaead13391ac4f5
https://doi.org/10.1371/journal.pone.0109284

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