Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Sean W. Minaker"'
Autor:
Shuhe Tsai, Louis-Alexandre Fournier, Emily Yun-Chia Chang, James P Wells, Sean W Minaker, Yi Dan Zhu, Alan Ying-Hsu Wang, Yemin Wang, David G Huntsman, Peter C Stirling
Publikováno v:
PLoS Genetics, Vol 17, Iss 4, p e1009238 (2021)
ARID1A is a core DNA-binding subunit of the BAF chromatin remodeling complex, and is lost in up to 7% of all cancers. The frequency of ARID1A loss increases in certain cancer types, such as clear cell ovarian carcinoma where ARID1A protein is lost in
Externí odkaz:
https://doaj.org/article/330f9ddec6dc43c09ea6f032eae0dc87
Publikováno v:
Cell Cycle
The GPN proteins are a conserved family of GTP-binding proteins that are involved in the assembly and subsequent import of RNA polymerase II and III. In this study, we sought to ascertain the specificity of yeast GPN2 for RNA polymerases by screening
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a927e835d5a98ee2fc21bb50ad7591b5
https://europepmc.org/articles/PMC8344759/
https://europepmc.org/articles/PMC8344759/
Autor:
David G. Huntsman, Yemin Wang, Alan Ying-Hsu Wang, Peter C. Stirling, James P. Wells, Yi Dan Zhu, Emily Yun-Chia Chang, Sean W. Minaker, Shuhe Tsai, Louis-Alexandre Fournier
Publikováno v:
PLoS Genetics
PLoS Genetics, Vol 17, Iss 4, p e1009238 (2021)
PLoS Genetics, Vol 17, Iss 4, p e1009238 (2021)
ARID1A is a core DNA-binding subunit of the BAF chromatin remodeling complex, and is lost in up to 7% of all cancers. The frequency of ARID1A loss increases in certain cancer types, such as clear cell ovarian carcinoma where ARID1A protein is lost in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::80302d90787bea7c6821ea9e572c10b5
http://europepmc.org/articles/PMC8055027
http://europepmc.org/articles/PMC8055027
Autor:
Volker Lipka, Charlotte Roth, Marcel Wiermer, Sean W. Minaker, Yan Huang, Philip Hieter, Shuai Huang, Xin Li
Publikováno v:
The Plant Cell. 26:485-496
Proteins with nucleotide binding and leucine-rich repeat domains (NLRs) serve as immune receptors in animals and plants that recognize pathogens and activate downstream defense responses. As high accumulation of NLRs can result in unwarranted autoimm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52bc851392451d873e10a7ce973030b5
https://doi.org/10.1105/tpc.113.119057
https://doi.org/10.1105/tpc.113.119057
Publikováno v:
Genetics
The GPN proteins are a poorly characterized and deeply evolutionarily conserved family of three paralogous small GTPases, Gpn1, 2, and 3. The founding member, GPN1/NPA3/XAB1, is proposed to function in nuclear import of RNA polymerase II along with a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bc745284ca75548a2daa22ec803e4166
https://doi.org/10.1534/genetics.112.148726
https://doi.org/10.1534/genetics.112.148726
Publikováno v:
G3: Genes|Genomes|Genetics
The concept of synthetic lethality has gained popularity as a rational guide for predicting chemotherapeutic targets based on negative genetic interactions between tumor-specific somatic mutations and a second-site target gene. One hallmark of most c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::724cd8c4595d8679862bf91506355d6c
https://doi.org/10.1534/g3.112.004754
https://doi.org/10.1534/g3.112.004754
Autor:
Yujia Alina Chan, I. J. Barrett, Maria J. Aristizabal, Peter C. Stirling, Payal Sipahimalani, Michael S. Kobor, Philip Hieter, Sean W. Minaker
Publikováno v:
Genesdevelopment. 26(2)
Genome instability via RNA:DNA hybrid-mediated R loops has been observed in mutants involved in various aspects of transcription and RNA processing. The prevalence of this mechanism among essential chromosome instability (CIN) genes remains unclear.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c08fc5e6eeb810d6a1008c2855449249
https://pubmed.ncbi.nlm.nih.gov/22279048
https://pubmed.ncbi.nlm.nih.gov/22279048