Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Sean W C Chen"'
Publikováno v:
American Journal of Physiology-Renal Physiology. 298:F1041-F1050
We previously showed that the inhalational anesthetic isoflurane protects against renal proximal tubule necrosis via isoflurane-mediated stimulation and translocation of sphingosine kinase-1 (SK1) with subsequent synthesis of sphingosine-1-phosphate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da4173394587998bbf083c9ff2a8ca55
https://doi.org/10.1152/ajprenal.00115.2009
https://doi.org/10.1152/ajprenal.00115.2009
Publikováno v:
Journal of Pharmacology and Experimental Therapeutics. 333:736-747
Hepatic ischemia reperfusion (IR) injury causes acute kidney injury (AKI). However, the contribution of AKI to the pathogenesis of liver IR injury is unclear. Furthermore, controversy still exists regarding the role of A(1) adenosine receptors (A(1)A
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8511d8a264fc1cfbd5f8952fd7088f2d
https://doi.org/10.1124/jpet.110.166884
https://doi.org/10.1124/jpet.110.166884
Publikováno v:
Laboratory Investigation. 90:476-495
Acute kidney injury (AKI) is frequent after liver ischemia reperfusion (IR) can potentiate liver injury and is often complicated by subsequent multiorgan dysfunction syndrome. AKI because of liver IR is characterized by early renal endothelial cell a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c90db2a8e2b3fc7648f2cbc1e321d35
https://doi.org/10.1038/labinvest.2009.143
https://doi.org/10.1038/labinvest.2009.143
Publikováno v:
Shock. 33:31-42
Hepatic ischemia/reperfusion (I/R) injury is a major complication after liver transplantation, major hepatic resection, or prolonged portal vein occlusion. Furthermore, acute kidney injury is frequent after hepatic I/R and greatly increases postopera
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ac66d4ff3e14ae04429b48b6907b021
https://doi.org/10.1097/shk.0b013e3181c02c1f
https://doi.org/10.1097/shk.0b013e3181c02c1f
Autor:
Sang Won Park, Kevin M. Brown, Joseph Song, Vivette D. D'Agati, Minjae Kim, H. Thomas Lee, Mihwa Kim, Sean W. C. Chen, Jacqueline de Belleroche, Dominic J. Wells
Publikováno v:
Kidney International. 75:499-510
We previously showed that activation of the A1 adenosine receptor protected the kidney against ischemia–reperfusion injury by induction and phosphorylation of heat shock protein 27 (HSP27). Here, we used mice that overexpress human HSP27 (huHSP27)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e460ca576e87570a8cb9f69323a9a40
https://doi.org/10.1038/ki.2008.572
https://doi.org/10.1038/ki.2008.572
Publikováno v:
The Journal of Neuroscience. 26:233-240
Early in ontogeny, young rats must be able to detect dangerous stimuli and to exhibit appropriate defensive behaviors. Different nuclei of the amygdala mediate unconditioned and conditioned fear responses to threat in adult rats. The aim of this stud
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::74e4b6d6051fb09105df4527aafd950b
https://doi.org/10.1523/jneurosci.2890-05.2006
https://doi.org/10.1523/jneurosci.2890-05.2006
Autor:
H. Thomas Lee, Sang Won Park, Kevin M. Brown, Vivette D. D'Agati, Mihwa Kim, Sean W. C. Chen, Jay K. Kolls
Publikováno v:
Laboratory investigation; a journal of technical methods and pathology
Patients with acute kidney injury (AKI) frequently suffer from extra-renal complications including hepatic dysfunction and systemic inflammation. We aimed to determine the mechanisms of AKI-induced hepatic dysfunction and systemic inflammation. Mice
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a3c0e94388c01edcee4a594653a0ede3
https://pubmed.ncbi.nlm.nih.gov/20697374
https://pubmed.ncbi.nlm.nih.gov/20697374
Autor:
William T. Gerthoffer, Vivette D. D'Agati, H. Thomas Lee, Mihwa Kim, Sean W. C. Chen, Sang Won Park, Minjae Kim
Publikováno v:
American journal of physiology. Renal physiology. 299(2)
We have previously shown that exogenous and endogenous A1adenosine receptor (A1AR) activation protected against renal ischemia-reperfusion (IR) injury in mice by induction and phosphorylation of heat shock protein 27 (HSP27). With global overexpressi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0594d95d5d6b2bca42f78e7b84f0eebf
https://pubmed.ncbi.nlm.nih.gov/20484296
https://pubmed.ncbi.nlm.nih.gov/20484296
Publikováno v:
Laboratory investigation; a journal of technical methods and pathology
Liver failure due to ischemia and reperfusion (IR) and subsequent acute kidney injury are significant clinical problems. We showed previously that liver IR selectively reduced plasma sphinganine-1-phosphate levels without affecting sphingosine-1-phos
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cf1985a13afdd7d8e2e72faef5b1cfe5
https://pubmed.ncbi.nlm.nih.gov/20458275
https://pubmed.ncbi.nlm.nih.gov/20458275
Publikováno v:
American journal of physiology. Renal physiology. 297(4)
Liver ischemia-reperfusion injury (IRI) causes acute kidney injury (AKI) in mice characterized by renal endothelial cell apoptosis, renal tubular necrosis, inflammation, and filamentous (F)-actin disruption. Since heat shock protein 27 (HSP27) protec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::689b12d38a8d4d0251bcbef60167acfb
https://pubmed.ncbi.nlm.nih.gov/19656912
https://pubmed.ncbi.nlm.nih.gov/19656912