Zobrazeno 1 - 10
of 105
pro vyhledávání: '"Sean V, Murphy"'
Autor:
Timothy Leach, Uma Gandhi, Kimberly D. Reeves, Kristina Stumpf, Kenichi Okuda, Frank C. Marini, Stephen J. Walker, Richard Boucher, Jeannie Chan, Laura A. Cox, Anthony Atala, Sean V. Murphy
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-15 (2023)
Abstract The human airways are complex structures with important interactions between cells, extracellular matrix (ECM) proteins and the biomechanical microenvironment. A robust, well-differentiated in vitro culture system that accurately models thes
Externí odkaz:
https://doaj.org/article/f6aec4b9509d461d8e54e25cfb50ccb8
Autor:
Stefanos Giannakopoulos, Daniel P Strange, Boonyanudh Jiyarom, Omar Abdelaal, Aaron W Bradshaw, Vivek R Nerurkar, Monika A Ward, Jackson Bakse, Jonathan Yap, Selena Vanapruks, William A Boisvert, Michelle D Tallquist, Cecilia Shikuma, Hooman Sadri-Ardekani, Philip Clapp, Sean V Murphy, Saguna Verma
Publikováno v:
PLoS Pathogens, Vol 19, Iss 5, p e1011409 (2023)
The hallmark of severe COVID-19 involves systemic cytokine storm and multi-organ injury including testicular inflammation, reduced testosterone, and germ cell depletion. The ACE2 receptor is also expressed in the resident testicular cells, however, S
Externí odkaz:
https://doaj.org/article/6b1acdcfa37143659be473ad6eb83ebc
Autor:
Oula Khoury, Cara Clouse, Malcolm K. McSwain, Jeffrey Applegate, Nancy D. Kock, Anthony Atala, Sean V. Murphy
Publikováno v:
Physiological Reports, Vol 10, Iss 20, Pp n/a-n/a (2022)
Abstract Inflammatory lung diseases affect millions of people worldwide. These diseases are caused by a number of factors such as pneumonia, sepsis, trauma, and inhalation of toxins. Pulmonary function testing (PFT) is a valuable functional methodolo
Externí odkaz:
https://doaj.org/article/26d8ebb9b9f44be9925b8c8d0a71b228
Autor:
Sean V. Murphy, Aleksander Skardal, Ronald A. Nelson Jr., Khiry Sunnon, Tanya Reid, Cara Clouse, Nancy D. Kock, John Jackson, Shay Soker, Anthony Atala
Publikováno v:
Stem Cells Translational Medicine, Vol 9, Iss 1, Pp 80-92 (2020)
Abstract There is a need for effective wound treatments that retain the bioactivity of a cellular treatment, but without the high costs and complexities associated with manufacturing, storing, and applying living biological products. Previously, we d
Externí odkaz:
https://doaj.org/article/f3a83fdd38d34788bd448cab9a77acb7
Publikováno v:
Stem Cells Translational Medicine, Vol 9, Iss 1, Pp 61-73 (2020)
Abstract Many immune‐mediated conditions are associated with a dysregulated imbalance toward a Th1 response leading to disease onset, severity, and damage. Many of the therapies such as immunomodulators or anti‐TNF‐α antibodies often fall shor
Externí odkaz:
https://doaj.org/article/86e1d3ad91974a4a81e495d5bf94b8a8
Autor:
Luiz Maracaja, Ashish K. Khanna, Sean V. Murphy, Danielle L.V. Maracaja, Magan R. Lane, Oula Khoury, Josh Tan, Naresh Damuka, Freda F. Crawford, Joseph A. Bottoms, Mack D. Miller, David W. Kaczka, James Eric Jordam, Kiran Kumar Solingapuram Sai
Publikováno v:
Journal of Aerosol Medicine and Pulmonary Drug Delivery. 36:20-26
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d40193d9f3de62f8fb57d231d2ba917c
https://doi.org/10.1089/jamp.2022.0013
https://doi.org/10.1089/jamp.2022.0013
Publikováno v:
Journal of Burn Care & Research. 44:S33-S41
There are an estimated 500,000 patients treated with full-thickness wounds in the United States every year. Fire-related burn injuries are among the most common and devastating types of wounds that require advanced clinical treatment. Autologous spli
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::11aaf3dc2d16621b9aa2ac6f48cf0e48
https://doi.org/10.1093/jbcr/irac126
https://doi.org/10.1093/jbcr/irac126
Autor:
Aleksander Skardal, Sean V. Murphy, Mahesh Devarasetty, Ivy Mead, Hyun-Wook Kang, Young-Joon Seol, Yu Shrike Zhang, Su-Ryon Shin, Liang Zhao, Julio Aleman, Adam R. Hall, Thomas D. Shupe, Andre Kleensang, Mehmet R. Dokmeci, Sang Jin Lee, John D. Jackson, James J. Yoo, Thomas Hartung, Ali Khademhosseini, Shay Soker, Colin E. Bishop, Anthony Atala
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-16 (2017)
Abstract Many drugs have progressed through preclinical and clinical trials and have been available – for years in some cases – before being recalled by the FDA for unanticipated toxicity in humans. One reason for such poor translation from drug
Externí odkaz:
https://doaj.org/article/545c3d4e24814f1fb722fae0fa19632f
Publikováno v:
Gels, Vol 7, Iss 1, p 13 (2021)
Hydrogels have played a significant role in many applications of regenerative medicine and tissue engineering due to their versatile properties in realizing design and functional requirements. However, as bioengineered solutions are translated toward
Externí odkaz:
https://doaj.org/article/feaad00694314442b0e1a262ab05d72b
Publikováno v:
Biomedical Engineering and Computational Biology, Vol 2016, Iss Suppl. 1, Pp 35-38 (2016)
Externí odkaz:
https://doaj.org/article/c5b275c6c18a4f409f95a586cda56aab