Zobrazeno 1 - 10
of 40
pro vyhledávání: '"Sean Uryu"'
Autor:
Carlos J Diaz Osterman, Duygu Ozmadenci, Elizabeth G Kleinschmidt, Kristin N Taylor, Allison M Barrie, Shulin Jiang, Lisa M Bean, Florian J Sulzmaier, Christine Jean, Isabelle Tancioni, Kristen Anderson, Sean Uryu, Edward A Cordasco, Jian Li, Xiao Lei Chen, Guo Fu, Marjaana Ojalill, Pekka Rappu, Jyrki Heino, Adam M Mark, Guorong Xu, Kathleen M Fisch, Vihren N Kolev, David T Weaver, Jonathan A Pachter, Balázs Győrffy, Michael T McHale, Denise C Connolly, Alfredo Molinolo, Dwayne G Stupack, David D Schlaepfer
Publikováno v:
eLife, Vol 8 (2019)
Gene copy number alterations, tumor cell stemness, and the development of platinum chemotherapy resistance contribute to high-grade serous ovarian cancer (HGSOC) recurrence. Stem phenotypes involving Wnt-β-catenin, aldehyde dehydrogenase activities,
Externí odkaz:
https://doaj.org/article/7193db572cdc40948c8a07915a6afd96
Autor:
David D. Schlaepfer, Kristy K. Ward, Xiao Lei Chen, Christine Jean, Nichol L.G. Miller, Christine Lawson, Nina R. Shah, Florian J. Sulzmaier, Sean Uryu, Isabelle Tancioni
Ovarian cancer ascites fluid contains matrix proteins that can impact tumor growth via integrin receptor binding. In human ovarian tumor tissue arrays, we find that activation of the cytoplasmic focal adhesion (FAK) tyrosine kinase parallels increase
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7ac1b1840717d1064c3d76e5e14fdffb
https://doi.org/10.1158/1535-7163.c.6536671.v1
https://doi.org/10.1158/1535-7163.c.6536671.v1
Autor:
David D. Schlaepfer, Kristy K. Ward, Xiao Lei Chen, Christine Jean, Nichol L.G. Miller, Christine Lawson, Nina R. Shah, Florian J. Sulzmaier, Sean Uryu, Isabelle Tancioni
PDF file - 44K, Antibodies, DNA plasmids, and probe sets used in this study.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::389bcf6f4d4bc4675a972b519b0df800
https://doi.org/10.1158/1535-7163.22501075.v1
https://doi.org/10.1158/1535-7163.22501075.v1
Autor:
David D. Schlaepfer, Kristy K. Ward, Xiao Lei Chen, Christine Jean, Nichol L.G. Miller, Christine Lawson, Nina R. Shah, Florian J. Sulzmaier, Sean Uryu, Isabelle Tancioni
PDF file - 138K, Integrin surface expression in HEY beta5 integrin knockdown cells.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7bad3cb68c7f44fc36c2ac683521ee83
https://doi.org/10.1158/1535-7163.22501081
https://doi.org/10.1158/1535-7163.22501081
Autor:
David D. Schlaepfer, Kristy K. Ward, Xiao Lei Chen, Christine Jean, Nichol L.G. Miller, Christine Lawson, Nina R. Shah, Florian J. Sulzmaier, Sean Uryu, Isabelle Tancioni
PDF file - 66K, qPCR verification of beta5 transcripts.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4022cb8c8726f55e8828073b6839513e
https://doi.org/10.1158/1535-7163.22501084.v1
https://doi.org/10.1158/1535-7163.22501084.v1
Autor:
David D. Schlaepfer, Kristy K. Ward, Xiao Lei Chen, Christine Jean, Nichol L.G. Miller, Christine Lawson, Nina R. Shah, Florian J. Sulzmaier, Sean Uryu, Isabelle Tancioni
PDF file - 315K, Cell survival and cell cycle progression analyses of VS-4718 FAK inhibitor sensitive (HEY and OVCAR8) and resistant (OVCAR10 and SKOV3-IP) cells.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::18b564e1005f3b1507a748c5cbd68aa0
https://doi.org/10.1158/1535-7163.22501090
https://doi.org/10.1158/1535-7163.22501090
Autor:
David D. Schlaepfer, Kristy K. Ward, Xiao Lei Chen, Christine Jean, Nichol L.G. Miller, Christine Lawson, Nina R. Shah, Florian J. Sulzmaier, Sean Uryu, Isabelle Tancioni
PDF file - 112K, Pharmacological FAK inhibition decreases beta5 integrin and osteopontin (OPN) levels in ID8-IP cells in vivo.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b4bb7e47bc294c0a3a17d6793dde864c
https://doi.org/10.1158/1535-7163.22501087
https://doi.org/10.1158/1535-7163.22501087
Autor:
David D. Schlaepfer, Kristy K. Ward, Xiao Lei Chen, Christine Jean, Nichol L.G. Miller, Christine Lawson, Nina R. Shah, Florian J. Sulzmaier, Sean Uryu, Isabelle Tancioni
PDF file - 894K, FAK and pY397 FAK immunostaining of human tissue array.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e7ab9f3a945117be4af468e0fc45cbc
https://doi.org/10.1158/1535-7163.22501093.v1
https://doi.org/10.1158/1535-7163.22501093.v1
Autor:
David D. Schlaepfer, Kristy K. Ward, Xiao Lei Chen, Christine Jean, Nichol L.G. Miller, Christine Lawson, Nina R. Shah, Florian J. Sulzmaier, Sean Uryu, Isabelle Tancioni
PDF file - 70K, Background information on the breast and ovarian carcinoma cell lines used in this study.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::339282b547836a8e9cef19688a5cd1f4
https://doi.org/10.1158/1535-7163.22501072
https://doi.org/10.1158/1535-7163.22501072
Autor:
David D. Schlaepfer, Kristy K. Ward, Xiao Lei Chen, Christine Jean, Nichol L.G. Miller, Christine Lawson, Nina R. Shah, Florian J. Sulzmaier, Sean Uryu, Isabelle Tancioni
PDF file - 59K
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e04892965fbc71f810b476d054cc069
https://doi.org/10.1158/1535-7163.22501078
https://doi.org/10.1158/1535-7163.22501078