Výsledky vyhledávání - "Sean T. Nguyen"

A systematic review of the effect of delayed appropriate antibiotic treatment on the outcomes of patients with severe bacterial infections

Autor: Keiko Tone, Jordi Rello, Giovanni Sotgiu, Rachael McCool, Jacoby V. Patterson, Sean T. Nguyen, Matteo Bassetti, Christopher Longshaw, Davide Manissero, Mick Arber, Sara Lopes, Stefano Aliberti, Francesco Blasi, Herman Goossens, Evan J Zasowski, Lara Tavoschi

Publikováno v: Chest

BACKGROUND: Patients with severe bacterial infections often experience delay in receiving appropriate treatment. Consolidated evidence of the impact of delayed appropriate treatment is needed to guide treatment and improve outcomes. RESEARCH QUESTION

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec7b37d089cba99b48d871476dfef426
https://hdl.handle.net/10067/1720090151162165141

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Systematic review of the impact of appropriate versus inappropriate initial antibiotic therapy on outcomes of patients with severe bacterial infections

Autor: Jacoby V. Patterson, Stefano Aliberti, Christopher Longshaw, Lara Tavoschi, Herman Goossens, Giovanni Sotgiu, Jordi Rello, Evan J Zasowski, Rachael McCool, Davide Manissero, Keiko Tone, Francesco Blasi, Sean T. Nguyen, Mick Arber, Matteo Bassetti, Sara Lopes

Publikováno v: International journal of antimicrobial agents

We investigated the impact of appropriate versus inappropriate initial antimicrobial therapy on the clinical outcomes of patients with severe bacterial infections as part of a systematic review and meta-analyses assessing the impact of delay in appro

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::03ca2c8bb2c3cc908ae9771d4a5fa44b
http://hdl.handle.net/11568/1062831

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Meropenem time above the MIC exposure is predictive of response in cystic fibrosis children with acute pulmonary exacerbations

Autor: Natalie Neu, Lisa Saiman, Sean T. Nguyen, Marianne S. Muhlebach, Jeffrey J. Cies, Rebecca S. Pettit, Craig Lapin, Kimberly J. Novak, David P. Nicolau, Joseph L. Kuti

Publikováno v: Diagnostic Microbiology and Infectious Disease. 91:294-297

Meropenem exposures from 15 children (8-17 years old) with cystic fibrosis (CF) acute pulmonary exacerbation were analyzed to define the pharmacodynamic threshold required for a positive response. The primary endpoint was the relative increase in for

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::04486a54c3689dd9d4411918573fff51
https://doi.org/10.1016/j.diagmicrobio.2018.01.020

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Antibiotic Stewardship Challenges in a Referral Neonatal Intensive Care Unit

Autor: Stephanie Karasick, Sean T. Nguyen, Tracy Chiang, Kayla Quick, Joseph B. Cantey, Kimberly D. Shipp

Publikováno v: American Journal of Perinatology. 33:518-524

Antibiotic overuse in neonates is associated with adverse outcomes. Data are limited to guide antibiotic stewardship in the neonatal intensive care unit (NICU). Our objective was to identify areas for antibiotic stewardship improvement in a referral

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::119c574cab9c93eeb3c73c8cc466d658
https://doi.org/10.1055/s-0035-1569990

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692. In Vitro Antibacterial Activity of Cefiderocol Against a Multi-national Collection of Carbapenem-Nonsusceptible Gram-Negative Bacteria From Respiratory Infections: SIDERO-WT-2014–2017

Autor: Daniel F. Sahm, Sean T Nguyen, Meredith M Hackel, Roger Echols, Sonia N Rao, Jennifer M. Hayes, Masakatsu Tsuji, Yoshinori Yamano, Melinda M. Soriano, Glenn S. Tillotson

Publikováno v: Open Forum Infectious Diseases

Background Cefiderocol (CFDC) is a new siderophore cephalosporin with potent in vitro activity against a broad range of Gram-negative (GN) pathogens, including carbapenem-nonsusceptible (Carb-NS) strains. We evaluated the in vitro activity of CFDC an

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d7b82f61f859a1674fa966eb8999272
https://doi.org/10.1093/ofid/ofz360.760

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Microbiological activity of ceftolozane/tazobactam, ceftazidime, meropenem, and piperacillin/tazobactam against Pseudomonas aeruginosa isolated from children with cystic fibrosis

Autor: Sean T. Nguyen, Jeffrey J. Cies, David P. Nicolau, Rebecca S. Pettit, Craig Lapin, Marianne S. Muhlebach, Kimberly J. Novak, Joseph L. Kuti, Natalie Neu, Lisa Saiman

Publikováno v: Diagnostic Microbiology and Infectious Disease. 83:53-55

The activity of ceftolozane/tazobactam was tested against 50 nonduplicate Pseudomonas aeruginosa from 18 cystic fibrosis children collected in 2012-2014. These isolates were multidrug resistant with susceptibility to meropenem, ceftazidime, and piper

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e4b56490109001a7e8bbb1331609e171
https://doi.org/10.1016/j.diagmicrobio.2015.04.012

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Probiotic-Associated Aspiration Pneumonia Due to Lactobacillus rhamnosus

Autor: Christopher D. Doern, Folashade Afolabi, Sean T. Nguyen, Carey-Ann D. Burnham

Publikováno v: Journal of Clinical Microbiology. 52:3124-3126

Lactobacilli are low-virulence, commensal organisms of the gastrointestinal and genitourinary tracts and are commonly used as “probiotic supplements.” Herein, we describe an episode of respiratory syncytial virus (RSV) bronchiolitis with bacteria

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::382674aca3689f8a79a8c0b30873ce01
https://doi.org/10.1128/jcm.01065-14

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Multicenter Evaluation of Vancomycin Dosing: Emphasis on Obesity

Autor: Amy M. Bain, Roger Bedimo, Anita P. Rahman, Stephen L. Vu, Susan A. Eaton, Ronald G. Hall, Sean T. Nguyen, Anthony J. Busti, Kenna D. Payne

Publikováno v: The American Journal of Medicine. 121:515-518

There is a paucity of data available regarding the dosing of antimicrobials in obesity. However, data are available demonstrating that vancomycin should be dosed on the basis of actual body weight.This study was conducted at 2 tertiary care medical c

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::22fa72857ca463e2a1f082eed2c580b9
https://doi.org/10.1016/j.amjmed.2008.01.046

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Efficacy of Pravastatin in Non-Nucleoside Reverse Transcriptase Inhibitor (NNRTI) and Protease Inhibitor (PI)-based HAART in HIV-Infected Patients

Autor: Amy M. Baia, Anita P. Rahman, Sean T. Nguyen, Susan A. Eaton, Kenna D. Payne, Anthony J. Busti

Publikováno v: American Journal of Infectious Diseases. 4:124-130

Pravastatin has generally been considered a safe and effective option for HIV-infected patients on highly active antiretroviral therapy (HAART). However, pravastatin concentrations are known to significantly decrease with concomitant efavirenz (EFV)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::fe50c93d266842a2157a97241c0451d4
https://doi.org/10.3844/ajidsp.2008.124.130

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