Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Sean T H, Liu"'
Autor:
Douglas Tremblay, Carina Seah, Thomas Schneider, Sheena Bhalla, Jonathan Feld, Leonard Naymagon, Bo Wang, Vaibhav Patel, Tomi Jun, Thomas Jandl, Farah Rahman, Sean T. H. Liu, Judith A. Aberg, Nicole Bouvier, The Mount Sinai Health System Convalescent Plasma Team
Publikováno v:
Cancer Medicine, Vol 9, Iss 22, Pp 8571-8578 (2020)
Abstract Background Patients with malignancy are particularly vulnerable to infection with Severe Acute Respiratory Disease‐Coronavirus‐2 (SARS‐CoV‐2) given their immunodeficiency secondary to their underlying disease and cancer‐directed th
Externí odkaz:
https://doaj.org/article/068733c822c64310bf05c9b722579ef7
Autor:
Hung-Mo Lin, Sean T. H. Liu, Matthew A. Levin, John Williamson, Nicole M. Bouvier, Judith A. Aberg, David Reich, Natalia Egorova
Publikováno v:
Life, Vol 13, Iss 1, p 210 (2023)
(1) Background: Several retrospective observational analyzed treatment outcomes for COVID-19; (2) Methods: Inverse probability of censoring weighting (IPCW) was applied to correct for bias due to informative censoring in database of hospitalized pati
Externí odkaz:
https://doaj.org/article/9ab274f5164e47fa9720a54a8cd3c3fd
Publikováno v:
Vaccines, Vol 9, Iss 6, p 660 (2021)
Fc-dependent effector functions are an important determinant of the in vivo potency of therapeutic antibodies. Effector function is determined by the combination of FcRs bound by the antibody and the cell expressing the relevant FcRs, leading to anti
Externí odkaz:
https://doaj.org/article/e43f319db2504c33994d953592c6bd25
Autor:
Sean T. H. Liu, Mila Mirceta, Grace Lin, Deborah M. Anderson, Tarashon Broomes, Alina Jen, Ashley Abid, David Reich, Christine Hall, Judith A. Aberg
Publikováno v:
Antimicrobial Agents and Chemotherapy.
Anti-SARS-CoV-2 immunoglobulin (human) investigational product (COVID-HIGIV) is a purified immunoglobulin preparation containing SARS-CoV-2 polyclonal antibodies. This single-center clinical trial aimed to characterize the safety and pharmacokinetics
Autor:
Michael J. Joyner, Rickey E. Carter, Sean T. H. Liu, Patrick W. Johnson, Eric Salazar, Brenda J. Grossman, James M. Musser, Chad C. Wiggins, Stephen A. Klassen, Arturo Casadevall, Jeffrey P. Henderson, Jonathon W. Senefeld, Sarah E. Baker, Nigel Paneth, William R. Hartman, Katelyn A. Bruno, Zhen Wang, R. Scott Wright, Noud van Helmond, De Lisa Fairweather, Nicole M. Bouvier, Liise Anne Pirofski, Shmuel Shoham
Publikováno v:
Mayo Clinic Proceedings
Mayo Clinic Proceedings, 96, 5, pp. 1262-1275
Mayo Clinic Proceedings, 96, 1262-1275
Mayo Clinic Proceedings, 96, 5, pp. 1262-1275
Mayo Clinic Proceedings, 96, 1262-1275
Contains fulltext : 235066.pdf (Publisher’s version ) (Open Access) To determine the effect of COVID-19 convalescent plasma on mortality, we aggregated patient outcome data from 10 randomized clinical trials, 20 matched control studies, 2 dose-resp
Autor:
Allen C. Cheng, Jose Polanco, Florian Krammer, Jussi Hepojoki, Erna Milunka Kojic, Thomas M. Moran, Katherine Kedzierska, Daniel Stadlbauer, Teresa Aydillo, Veronika Chromikova, Kaijun Jiang, Luz Amarilis Lugo, Maria Bermudez-Gonzalez, Philip L. Felgner, Charlotte Cunningham-Rundles, Thi H. O. Nguyen, Viviana Simon, Meagan McMahon, Guha Asthagiri Arunkumar, Fatima Amanat, Shirin Strohmeier, Giulio Kleiner, Sean T. H. Liu, Denise Jurczyszak, Daniel Caplivski, Lisa Miorin, Olli Vapalahti, Daniel S. Fierer, Jonathan Stoever, Adolfo García-Sastre
Publikováno v:
Nat Med
medRxiv
article-version (status) pre
article-version (number) 2
Nature Medicine
medRxiv
article-version (status) pre
article-version (number) 2
Nature Medicine
SARS-Cov-2 (severe acute respiratory disease coronavirus 2), which causes Coronavirus Disease 2019 (COVID19) was first detected in China in late 2019 and has since then caused a global pandemic. While molecular assays to directly detect the viral gen
Autor:
Natalie J. Hamel, Jenna J. Guthmiller, Florian Krammer, Nai-Ying Zheng, Alec W. Freyn, Andrew B. Ward, Lei Li, Micah E. Tepora, Henry A. Utset, Peter Palese, Olivia Stovicek, Raffael Nachbagauer, Siriruk Changrob, Patrick C. Wilson, Min Huang, Julianna Han, Christopher T. Stamper, Haley L. Dugan, Dalia J. Bitar, Sean T. H. Liu
Publikováno v:
Sci Transl Med
Broadly neutralizing antibodies are critical for protection against both drifted and shifted influenza viruses. Here, we reveal that first exposure to the 2009 pandemic H1N1 influenza virus recalls memory B cells that are specific to the conserved re
Publikováno v:
Vaccines
Volume 9
Issue 6
Vaccines, Vol 9, Iss 660, p 660 (2021)
Volume 9
Issue 6
Vaccines, Vol 9, Iss 660, p 660 (2021)
Fc-dependent effector functions are an important determinant of the in vivo potency of therapeutic antibodies. Effector function is determined by the combination of FcRs bound by the antibody and the cell expressing the relevant FcRs, leading to anti
Autor:
Peter Palese, Victoria C. Rosado, Florian Krammer, Jenna J. Guthmiller, Viviana Simon, Mark J. Bailey, Veronika Chromikova, Andrew B. Ward, Julianna Han, Alec W. Freyn, Karlynn E. Neu, Sean T. H. Liu, Hannah L. Turner, Raffael Nachbagauer, Patrick C. Wilson, Shirin Strohmeier, Min Huang
Publikováno v:
Proc Natl Acad Sci U S A
In this study, we utilized a panel of human immunoglobulin (Ig) IgA monoclonal antibodies isolated from the plasmablasts of eight donors after 2014/2015 influenza virus vaccination (Fluarix) to study the binding and functional specificities of this i
Autor:
Svenja Weiss, Gospel Enyindah-Asonye, Vincenza Itri, Sean T. H. Liu, Chuan-Tien Hung, Benhur Lee, Suzanne Arinsburg, Ian Baine, Jéromine Klingler, Catarina E. Hioe, Denise Jurczyszak, Jonathan Stoever, Kasopefoluwa Y. Oguntuyo, Susan Zolla-Pazner, Erna Milunka Kojic, Xiaomei Liu, Christian S. Stevens, Juan C. Bandres, Maria Bermudez-Gonzalez, Arthur Nádas, Satoshi Ikegame, Fatima Amanat
Publikováno v:
The Journal of Infectious Diseases
Background Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has infected millions of people globally. Virus infection requires the receptor-binding domain (RBD) of the spike protein. Although studies have demonstrated anti-spike and -RBD