Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Sean Sepulveda"'
Autor:
Massimo D’Apuzzo, Christine Brown, Behnam Badie, Jonathan Hibbard, Eric Ma, Maryam Aftabizadeh, Sharareh Gholamin, Heine Natri, Abbigael Aday, Sean Sepulveda, Gaby Sanchez, Nicholas Banovich
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss Suppl 1 (2023)
Externí odkaz:
https://doaj.org/article/95f55555a3904103ad6ff559a182cfe2
Autor:
Mark Cobbold, David M. Langenau, Weiguo Lu, David R. Spriggs, Bo R. Rueda, Michael S. Lawrence, Eleanor Minogue, Mei Guo, Dominique T. Zarrella, Lauren R. Whelton, Eric Alpert, Sean Sepulveda, Laura T. Morton, Adam Langenbucher, James M. Heather, Qiqi Yang, David G. Millar, Chuan Yan, Songfa Zhang
Antibody–peptide epitope conjugates (APEC) are a new class of modified antibody–drug conjugates that redirect T-cell viral immunity against tumor cells. APECs contain a tumor-specific protease cleavage site linked to a patient-specific viral epit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::79dbef811b4cd38494a2bce9ecdd065b
https://doi.org/10.1158/0008-5472.c.6513819
https://doi.org/10.1158/0008-5472.c.6513819
Autor:
Mark Cobbold, David M. Langenau, Weiguo Lu, David R. Spriggs, Bo R. Rueda, Michael S. Lawrence, Eleanor Minogue, Mei Guo, Dominique T. Zarrella, Lauren R. Whelton, Eric Alpert, Sean Sepulveda, Laura T. Morton, Adam Langenbucher, James M. Heather, Qiqi Yang, David G. Millar, Chuan Yan, Songfa Zhang
Supplementary Data from Antibody-Peptide Epitope Conjugates for Personalized Cancer Therapy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7495fc48d494f43cc3262f99c6257b6f
https://doi.org/10.1158/0008-5472.22431150
https://doi.org/10.1158/0008-5472.22431150
Autor:
Songfa Zhang, Chuan Yan, David G. Millar, Qiqi Yang, James M. Heather, Adam Langenbucher, Laura T. Morton, Sean Sepulveda, Eric Alpert, Lauren R. Whelton, Dominique T. Zarrella, Mei Guo, Eleanor Minogue, Michael S. Lawrence, Bo R. Rueda, David R. Spriggs, Weiguo Lu, David M. Langenau, Mark Cobbold
Publikováno v:
Cancer research. 82(5)
Antibody–peptide epitope conjugates (APEC) are a new class of modified antibody–drug conjugates that redirect T-cell viral immunity against tumor cells. APECs contain a tumor-specific protease cleavage site linked to a patient-specific viral epit
Autor:
Eleanor Minogue, James M. Heather, Rakesh R. Ramjiawan, Dai Fukumura, Songfa Zhang, Takashi Nojiri, Keehoon Jung, Leif W. Ellisen, Aditya Bardia, Laura T. Morton, Aaron N. Hata, Li Wan, Sean Sepulveda, Nisha Gupta, Ashok Khatri, Ryan B. Corcoran, Kohei Shigeta, Ricky Joseph, Feng Shi, Sara I. Pai, David Millar, Kosuke Kawaguchi, Jiang Chen, William Ho, Dan G. Duda, Mark Cobbold, Shuichi Aoki, Ivy X. Chen, Rakesh K. Jain
Publikováno v:
Nature biotechnology. 38(4)
Several cancer immunotherapy approaches, such as immune checkpoint blockade and adoptive T-cell therapy, boost T-cell activity against the tumor, but these strategies are not effective in the absence of T cells specific for displayed tumor antigens.
Autor:
James F. Brennan, Jolyon Terragni, Jose-Luis Medrano, Sean Sepulveda, Swati Banerjee, Julie R. Graham, Gauri Nayak, Geoffrey M. Cooper
Publikováno v:
Journal of Biological Chemistry. 286:36215-36227
Phosphatidylinositol (PI) 3-kinase/Akt signaling plays a critical role in cell proliferation and survival, partly by regulation of FoxO transcription factors. Previous work using global expression profiling indicated that inhibition of PI 3-kinase in
Autor:
Michael R. Rose, Parvin Shojaeian, Sean Sepulveda, Mahtab Jafari, Laurence D. Mueller, Casandra L. Rauser
Publikováno v:
Sepulveda, S; Shojaeian, P; Rauser, CL; Jafari, M; Mueller, LD; & Rose, MR. (2008). Interactions between injury, stress resistance, reproduction, and aging in Drosophila melanogaster. Experimental Gerontology, 43(3), 136-145. doi: 10.1016/j.exger.2007.10.006. UC Irvine: Retrieved from: http://www.escholarship.org/uc/item/5x43w4x6
An important aspect of the aging process in Drosophila melanogaster is the natural loss of antennae, legs, bristles, and parts of wings with age. These injuries lead to a loss of hemolymph, which contains water and nutrients. Stress-resistant lines o
Autor:
Millar, David G., Ramjiawan, Rakesh R., Kawaguchi, Kosuke, Gupta, Nisha, Chen, Jiang, Zhang, Songfa, Nojiri, Takashi, Ho, William W., Aoki, Shuichi, Jung, Keehoon, Chen, Ivy, Shi, Feng, Heather, James M., Shigeta, Kohei, Morton, Laura T., Sepulveda, Sean, Wan, Li, Joseph, Ricky, Minogue, Eleanor, Khatri, Ashok
Publikováno v:
Nature Biotechnology; Apr2020, Vol. 38 Issue 4, p420-425, 6p, 1 Diagram, 2 Graphs
Autor:
Tullai, John W.1, Tacheva, Silvia2, Owens, Laura J.1, Graham, Julie R.3, Cooper, Geoffrey M.1 gmcooper@bu.edu
Publikováno v:
PLoS ONE. 2011, Vol. 6 Issue 5, p1-9. 9p.
Does Aging Stop? reveals the most paradoxical finding of recent aging research: the cessation of demographic aging. The authors show that aging stops at the level of the individual organism, and explain why evolution allows this. The implications of