Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Sean S Parghi"'
Autor:
Elena V Linardopoulou, Sean S Parghi, Cynthia Friedman, Gregory E Osborn, Susan M Parkhurst, Barbara J Trask
Publikováno v:
PLoS Genetics, Vol 3, Iss 12, p e237 (2007)
Subtelomeres are duplication-rich, structurally variable regions of the human genome situated just proximal of telomeres. We report here that the most terminally located human subtelomeric genes encode a previously unrecognized third subclass of the
Externí odkaz:
https://doaj.org/article/aabc5285b1f84d54aab6db1a45e4785e
Autor:
M Katharine Rudd, Cynthia Friedman, Sean S Parghi, Elena V Linardopoulou, Li Hsu, Barbara J Trask
Publikováno v:
PLoS Genetics, Vol 3, Iss 2, p e32 (2007)
Chromosome ends are known hotspots of meiotic recombination and double-strand breaks. We monitored mitotic sister chromatid exchange (SCE) in telomeres and subtelomeres and found that 17% of all SCE occurs in the terminal 0.1% of the chromosome. Telo
Externí odkaz:
https://doaj.org/article/adef68cc10b94e048e4721a4001415e4
Autor:
Damian Madan, Rafael Rivera, Corrie Ortega, Justin C. Touchon, Corinna Kimball, Geert-Jan van Gemert, Wouter Graumans, Stephanie Matsuura, Sean S. Parghi, David Bell, Teun Bousema, Chris Drakeley, Katharine A. Collins, Thomas R. Burkot
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-8 (2022)
Abstract Vector control strategies are among the most effective measures to combat mosquito-borne diseases, such as malaria. These strategies work by altering the mosquito age structure through increased mortality of the older female mosquitoes that
Externí odkaz:
https://doaj.org/article/f3a1d535e62e428e8e03851a5bd51e40
Autor:
Wright Nathan E, Sean S. Parghi, James Taylor, Matthew R. Warr, Stacey Drabic, Angie Hammond, Ethan Grant
Publikováno v:
Poster Presentations.
Background A hallmark of lupus is the presence of antinuclear autoantibodies, including those against RNA-protein complexes and double-stranded DNA (dsDNA).1,2 FcγR-mediated internalization of these nucleic acid:autoantibody immune complexes results
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3d72ea44a0ff54fd869779ccf305341e
https://doi.org/10.1136/annrheumdis-2019-eular.2511
https://doi.org/10.1136/annrheumdis-2019-eular.2511
Autor:
Janet M. Young, Rae Lynn M. Endicott, Megan Walker, Sean S Parghi, Barbara J. Trask, Jeffrey M. Kidd
Publikováno v:
The American Journal of Human Genetics. 83:228-242
As much as a quarter of the human genome has been reported to vary in copy number between individuals, including regions containing about half of the members of the olfactory receptor (OR) gene family. We have undertaken a detailed study of copy-numb
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::943d6aa900c46cdcfe53467e4d939d92
https://doi.org/10.1016/j.ajhg.2008.07.005
https://doi.org/10.1016/j.ajhg.2008.07.005
Publikováno v:
Oncogene. 27:3145-3155
The ability of tumor cells to metastasize is increasingly viewed as an interaction between the primary tumor and host tissues. Deletion of the p19/Arf or p53 tumor suppressor genes accelerates malignant progression and metastatic spread of 7,12-dimet
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dce761a630202e8aa2d153b4784389b7
https://doi.org/10.1038/sj.onc.1210973
https://doi.org/10.1038/sj.onc.1210973
Publikováno v:
Oncogene. 23:4413-4421
Avian leukosis virus (ALV) induces bursal lymphoma in tumor-susceptible chicken strains after proviral integration within the c-myc gene, and subsequent expansion of Myc-overexpressing lymphocytes within transformed follicles. Line 6(3) strain chicke
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::70ba225bdcdec27d6dd83c41f2741800
https://doi.org/10.1038/sj.onc.1207577
https://doi.org/10.1038/sj.onc.1207577
Autor:
Cynthia Friedman, Li Hsu, M. Katharine Rudd, Elena V. Linardopoulou, Sean S Parghi, Barbara J. Trask
Publikováno v:
PLoS Genetics, Vol 3, Iss 2, p e32 (2007)
PLoS Genetics
PLoS Genetics
Chromosome ends are known hotspots of meiotic recombination and double-strand breaks. We monitored mitotic sister chromatid exchange (SCE) in telomeres and subtelomeres and found that 17% of all SCE occurs in the terminal 0.1% of the chromosome. Telo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a1ac200516f2de20b2b32e40eb5408a6
http://europepmc.org/articles/PMC1802831?pdf=render
http://europepmc.org/articles/PMC1802831?pdf=render
Publikováno v:
Oncogene. 24(5)
Deregulated c-myc gene expression is associated with many human and animal cancers. Myc overexpression promotes the growth of blood and lymphatic vessels, which is due in part to induction of growth factors including vascular endothelial growth facto
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5aac2115fb2767bf6131302dab14cd25
https://pubmed.ncbi.nlm.nih.gov/15580293
https://pubmed.ncbi.nlm.nih.gov/15580293