Výsledky vyhledávání - "Sean Robert Wevrett"

Penetration of Flurbiprofen from a Locally Applied Sore Throat Lozenge and Spray into Cadaveric Human Pharynx Tissue: A Novel ex vivo Model and Microautoradiography Method

Autor: Sean Robert Wevrett, John Farrah, Suzanne Edmunds, Oluwajoba Adegoke, Anuradha Kulasekaran, Marc B. Brown, Rob Turner

Publikováno v: Clinical Pharmacology : Advances and Applications

Rob Turner,1 Sean Robert Wevrett,1 Suzanne Edmunds,1 Marc Brown,1 Anuradha Kulasekaran,2 Oluwajoba Adegoke,2 John Farrah2 1MedPharm Ltd, Guildford, UK; 2Reckitt Benckiser Healthcare International Ltd., Slough, Berkshire, UKCorrespondence: Oluwajoba A

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52fc17cf10dcc46178e88cd84ea8782c
https://doi.org/10.2147/cpaa.s284433

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Use of in vitro performance models in the assessment of drug delivery across the human nail for nail disorders

Autor: Marc B. Brown, Rob Turner, Sean Robert Wevrett

Publikováno v: Expert opinion on drug delivery. 15(10)

Onychomycosis is the most prevalent nail condition, affecting between 5% and 20% of the population in western countries. Oral therapies are not the treatment of choice due to poor patient compliance, high relapse rates, severe side effects, and contr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f65b7412613331a39727173c3a599b9
https://pubmed.ncbi.nlm.nih.gov/30173543

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Validation of an analytical method to quantify the permeation and penetration of flurbiprofen into human pharynx tissue

Autor: Sean Robert Wevrett, Tim Shea, Rob Turner, Marc B. Brown, Suzanne Edmunds, Robert Atkinson

Publikováno v: Biomedical Chromatography

The aim of this investigation was to develop receiver and extraction fluids, and subsequently validate an analytical method to quantify the permeation and penetration of flurbiprofen into human pharynx tissue using a Franz diffusion cell. The solubil

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a341a7d04368805df3cf004a33f1e51
https://pubmed.ncbi.nlm.nih.gov/30667527

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