Zobrazeno 1 - 10 of 10 pro vyhledávání: '"Sean R.R. Hall"'
1
Akademický článek
Functional and molecular characterization of PD1+ tumor-infiltrating lymphocytes from lung cancer patients
Autor: Jesse J. Lipp, Limei Wang, Haitang Yang, Feng Yao, Nathalie Harrer, Stefan Müller, Sabina Berezowska, Patrick Dorn, Thomas M. Marti, Ralph A. Schmid, Belazs Hegedüs, Abdallah Souabni, Sebastian Carotta, Mark A. Pearson, Wolfgang Sommergruber, Greg J. Kocher, Sean R.R. Hall
Publikováno v: OncoImmunology, Vol 11, Iss 1 (2022)
Antibody-mediated cancer immunotherapy targets inhibitory surface molecules, such as PD1, PD-L1, and CTLA-4, aiming to re-invigorate dysfunctional T cells. We purified and characterized tumor-infiltrating lymphocytes (TILs) and their patient-matched
Externí odkaz: https://doaj.org/article/9667d060bac747349286c601bb989662
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2
Akademický článek
Peritumoral CD90+CD73+ cells possess immunosuppressive features in human non-small cell lung cancer
Autor: Limei Wang, Haitang Yang, Patrick Dorn, Sabina Berezowska, Fabian Blank, Carlos Wotzkow, Thomas M. Marti, Ren-Wang Peng, Nathalie Harrer, Wolfgang Sommergruber, Gregor J. Kocher, Ralph A. Schmid, Sean R.R. Hall
Publikováno v: EBioMedicine, Vol 73, Iss , Pp 103664- (2021)
Summary: Background: Although T cell abundance in solid tumours is associated with better outcomes, it also correlates with a stroma-mediated source of immune suppression driven by TGFβ1 and poor overall survival. Whether this also is observed in no
Externí odkaz: https://doaj.org/article/1f7d51f1822442cc8888fbc4d5daa6bb
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4
Data from CRISPR-Mediated Kinome Editing Prioritizes a Synergistic Combination Therapy for FGFR1-Amplified Lung Cancer
Autor: Ren-Wang Peng, Ralph A. Schmid, Qinghua Zhou, Gregor J. Kocher, Thomas M. Marti, Sean R.R. Hall, Sabina Berezowska, Haibin Deng, Yanyun Gao, Rémy Bruggmann, Duo Xu, Haitang Yang, Shun-Qing Liang, Zhang Yang
Oncogenic activation of the FGFR pathway is frequent in lung and other cancers. However, due to drug resistance, pharmacological blockage of aberrant FGFR signaling has provided little clinical benefit in patients with FGFR-amplified tumors. The dete
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f0e46e934e3eb5b7c1c70f09556ebed
https://doi.org/10.1158/0008-5472.c.6513489.v1
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6
First Report on Ex Vivo Delivery of Paracrine Active Human Mesenchymal Stromal Cells to Liver Grafts During Machine Perfusion
Autor: Sean R.R. Hall, Clemens W G M Löwik, Ivo J Schurink, Martin J. Hoogduijn, Kairong Wang, Honglei Huang, Jan N. M. IJzermans, Jubi E. de Haan, Luc J. W. van der Laan, Laura Mezzanotte, R Yanto Ridwan, Jésus M Sierra Parraga, Jeroen de Jonge, Benedikt M. Kessler, Monique M A Verstegen
Publikováno v: Transplantation, 104, e5-e7. Lippincott Williams & Wilkins
Verstegen, Monique M A; Mezzanotte, Laura; Ridwan, R Yanto; Wang, Kairong; de Haan, Jubi; Schurink, Ivo J; Sierra Parraga, Jésus M; Hoogduijn, Martin; Kessler, Benedikt M; Huang, Honglei; Hall, Sean R. R.; IJzermans, Jan N M; Löwik, Clemens W G M; van der Laan, Luc J W; de Jonge, Jeroen (2019). First Report on Ex vivo Delivery of Paracrine Active Human Mesenchymal Stromal Cells to Liver Grafts During Machine Perfusion. Transplantation, 104(1), e5-e7. Lippincott Williams & Wilkins 10.1097/TP.0000000000002986
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f60b48099bba5cf39502e51726f830ea
https://pure.eur.nl/en/publications/6fc8b56c-8967-444a-b1be-6a851a61e79d
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7
Identification and Isolation of Small CD44-Negative Mesenchymal Stem/Progenitor Cells From Human Bone Marrow Using Elutriation and Polychromatic Flow Cytometry
Autor: Elizabeth Leary, David W. O'Neill, Greg Yavanian, Sean R.R. Hall, Sarah Eminli, Yajuan Jiang, Wayne A. Marasco
Publikováno v: Stem Cells Translational Medicine. 2:567-578
The method of isolation of bone marrow (BM) mesenchymal stem/stromal cells (MSCs) is a limiting factor in their study and therapeutic use. MSCs are typically expanded from BM cells selected on the basis of their adherence to plastic, which results in
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::82d95efd281dc817817c63d6a9fe6e35
https://doi.org/10.5966/sctm.2012-0155
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9
Support of Hepatic Regeneration by Trophic Factors from Liver-Derived Mesenchymal Stromal/Stem Cells
Autor: Sean R.R. Hall, Suomi M. G. Fouraschen, Luc J. W. van der Laan, Jeroen de Jonge
Publikováno v: Methods in Molecular Biology ISBN: 9781493914524
Mesenchymal stromal/stem cells (MSCs) have multilineage differentiation potential and as such are known to promote regeneration in response to tissue injury. However, accumulating evidence indicates that the regenerative capacity of MSCs is not via t
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::c95f745eaff17881c7e9b1dc96e2aee0
https://doi.org/10.1007/978-1-4939-1453-1_9
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