Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Sean R.A. Devenish"'
Autor:
Marc Emmenegger, Roland Worth, Sebastian Fiedler, Sean R.A. Devenish, Tuomas P.J. Knowles, Adriano Aguzzi
Publikováno v:
STAR Protocols, Vol 4, Iss 1, Pp 102095- (2023)
Summary: Conventional methods of measuring affinity are limited by artificial immobilization, large sample volumes, and homogeneous solutions. This protocol describes microfluidic antibody affinity profiling on complex human samples in solution to ob
Externí odkaz:
https://doaj.org/article/a1a74bf054e44e15908074e6ad2294c6
Autor:
Marc Emmenegger, Sebastian Fiedler, Silvio D. Brugger, Sean R.A. Devenish, Alexey S. Morgunov, Alison Ilsley, Francesco Ricci, Anisa Y. Malik, Thomas Scheier, Leyla Batkitar, Lidia Madrigal, Marco Rossi, Georg Meisl, Andrew K. Lynn, Lanja Saleh, Arnold von Eckardstein, Tuomas P.J. Knowles, Adriano Aguzzi
Publikováno v:
iScience, Vol 25, Iss 8, Pp 104766- (2022)
Summary: The B.1.1.529 (omicron) variant has rapidly supplanted most other SARS-CoV-2 variants. Using microfluidics-based antibody affinity profiling (MAAP), we have characterized affinity and IgG concentration in the plasma of 39 individuals with mu
Externí odkaz:
https://doaj.org/article/fde6b01a90544d528df0a5aabe263227
Autor:
Matthias M. Schneider, Tom Scheidt, Ashley J. Priddey, Catherine K. Xu, Mengsha Hu, Georg Meisl, Sean R.A. Devenish, Christopher M. Dobson, Vasilis Kosmoliaptsis, Tuomas P.J. Knowles
Publikováno v:
Biosensors and Bioelectronics. 228:115196
Antibody profiling is a fundamental component of understanding the humoral response in a wide range of disease areas. Most currently used approaches operate by capturing antibodies onto functionalised surfaces. Such measurements of surface binding ar