Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Sean R. Dinn"'
Autor:
Jason Castle, Allen L. Garner, Reginald D. Smith, Brian M. Davis, Steve Klopman, Sean R. Dinn, Andrew S. Torres, V. Bogdan Neculaes
Publikováno v:
IEEE Access, Vol 6, Pp 56395-56401 (2018)
The increasing use of activated platelet rich plasma (PRP), or platelet gel, for wound healing has highlighted the disadvantages of using bovine thrombin (BT), an animal derived platelet activator, including high cost and antibody stimulation. This h
Externí odkaz:
https://doaj.org/article/101ea7fe452e4a4ea3856924ddeb6820
Autor:
Deirdre A. Nelson, Charles Manhardt, Vidya Kamath, Yunxia Sui, Alberto Santamaria-Pang, Ali Can, Musodiq Bello, Alex Corwin, Sean R. Dinn, Michael Lazare, Elise M. Gervais, Sharon J. Sequeira, Sarah B. Peters, Fiona Ginty, Michael J. Gerdes, Melinda Larsen
Publikováno v:
Biology Open, Vol 2, Iss 5, Pp 439-447 (2013)
Summary Epithelial organ morphogenesis involves reciprocal interactions between epithelial and mesenchymal cell types to balance progenitor cell retention and expansion with cell differentiation for evolution of tissue architecture. Underlying subman
Externí odkaz:
https://doaj.org/article/f330b71b1b6944f7b3adfcb8fde714e6
Autor:
Karolina Nilsson, Ola Fjellström, Jan P. Mattsson, Xiaozhang Zheng, Kosrat Amin, Marianne Swanson, Thomas Elebring, William B. Geiss, Johan Gottfries, Christer Alstermark, Mohit Kothare, Peter R. Guzzo, Sverker von Unge, Sean R. Dinn, Alex M. Woo, James P. Harding, Anders Lehmann, Sunden Gunnel, Kevin Fitzpatrick, Anders Holmen, Michael J. Wyle
Publikováno v:
Journal of Medicinal Chemistry. 51:4315-4320
We have previously demonstrated that the prototypical GABA B receptor agonist baclofen inhibits transient lower esophageal sphincter relaxations (TLESRs), the most important mechanism for gastroesophageal reflux. Thus, GABA B agonists could be exploi
Autor:
Gregory L. Durst, Jim D. Durbin, John E. Reilly, Kendal T. Ryter, Lance Allen Pfeifer, Bryan H. Norman, Sean R. Dinn, Jeffrey Alan Dodge, Yong Wang, Venkatesh Krishnan, Timothy Ivo Richardson, Shengquan Liu
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 17:5082-5085
Benzopyrans are selective estrogen receptor (ER) beta agonists (SERBAs), which bind the ER receptor subtypes alpha and beta in opposite orientations. We have used structure based drug design to show that this unique phenomena can be exploited via sub
Publikováno v:
Tetrahedron Letters. 43:5685-5689
(Acyloxy)alkyl esters are commonly employed as prodrugs of carboxylic acid containing compounds. Several optically active (acyloxy)alkyl esters are prepared from a coupling and rearrangement reaction between optically active O-acyl-α-hydroxy acids a
Publikováno v:
ChemInform. 33
(Acyloxy)alkyl esters are commonly employed as prodrugs of carboxylic acid containing compounds. Several optically active (acyloxy)alkyl esters are prepared from a coupling and rearrangement reaction between optically active O-acyl-α-hydroxy acids a
Autor:
Ho-Shen Lin, Beatriz Lopez, Zhongping Huang, Eileen L. Considine, Yiu-Yin Cheung, Cora Sue Grossman, Philip Arthur Hipskind, Sean R. Dinn, Luisa M. Martín Cabrejas, John E. Reilly, Jose Eduardo Lopez, White Wesley Todd, Alfonso De Dios, Chuan Shih, Mary M. Mader, Karen Lynn Lobb, Michael Enrico Richett
Publikováno v:
Bioorganicmedicinal chemistry letters. 15(3)
The anti-proliferative activity of acylated heterocyclic sulfonamides is described in Vascular Endothelial Growth Factor-dependent Human Umbilical Vascular Endothelial Cells (VEGF-HUVEC) and in HCT116 tumor cells in a soft agar diffusion assay.
Autor:
Bai-Ping Ying, John Mehnert Schaus, David L. Nelson, Yao-Chang Xu, Joseph H. Krushinski, Sidney Xi Liang, Wendy H. Gough, Deyi Zhang, Sean R. Dinn, Suzanne E. Nutter, Daniel Timothy Kohlman, John Reilly, David B. Wainscott
Publikováno v:
Bioorganicmedicinal chemistry letters. 14(24)
Several fused bicyclic systems have been investigated to serve as the core structure of potent and selective 5-HT1F receptor agonists. Replacement of the indole nucleus in 2 with indazole and 'inverted' indazole provided more potent and selective 5-H
Autor:
Kendal T. Ryter, Peter R. Guzzo, Anton Daniel Kiefer, Anthony J. Sampognaro, Ronald N. Buckle, Sean R. Dinn, Michael Edward Flaugh, Ming Chou, Yao-Chang Xu, Steven W. Tregay
Publikováno v:
The Journal of organic chemistry. 68(3)
Methodology to prepare 8-amido-2-amino-1,2,3,4-tetrahydro-2-dibenzofurans, analogues with a fluorine substituent incorporated in the 6-, 7-, and 9-positions, and a difluorinated analogue with fluorines in the 6- and 9-positions is described. The tetr
Autor:
Thomas L. Williams, Stephen L. Senft, Jingjie Yeo, Francisco J. Martín-Martínez, Alan M. Kuzirian, Camille A. Martin, Christopher W. DiBona, Chun-Teh Chen, Sean R. Dinneen, Hieu T. Nguyen, Conor M. Gomes, Joshua J. C. Rosenthal, Matthew D. MacManes, Feixia Chu, Markus J. Buehler, Roger T. Hanlon, Leila F. Deravi
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-15 (2019)
Chromatophores in cephalopod skin are known for fast changes in coloration due to light-scattering pigment granules. Here, authors demonstrate structural coloration facilitated by reflectin in sheath cells and offer insights into the interplay betwee
Externí odkaz:
https://doaj.org/article/c42394c4ff5e4c258ce6b8af90a23f0b